Trispecific broadly neutralizing HIV antibodies mediate potent SHIV protection in macaques (Q41933491)

http://europepmc.org/abstract/PMC/5978417

10 July 2018

title

Trispecific broadly neutralizing HIV antibodies mediate potent SHIV protection in macaques (English)

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http://europepmc.org/abstract/PMC/5978417

10 July 2018

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28931639%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

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14 June 2020

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14 June 2020

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14 June 2020

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14 June 2020

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14 June 2020

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14 June 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28931639%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

Mangaiarkarasi Asokan

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14 June 2020

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14 June 2020

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14 June 2020

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14 June 2020

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14 June 2020

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14 June 2020

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14 June 2020

Richard A Koup

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14 June 2020

John-Paul Todd

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14 June 2020

Sijy O'Dell

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14 June 2020

Krisha McKee

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14 June 2020

Zachary Mankoff

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14 June 2020

Ling Xu

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14 June 2020

Ronnie R Wei

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14 June 2020

Gejing Deng

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14 June 2020

Lan Wu

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14 June 2020

Robert T Bailer

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14 June 2020

Keyun Wang

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14 June 2020

Zhi-Yong Yang

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14 June 2020

language of work or name

English

0 references

publication date

20 September 2017

1 reference

http://europepmc.org/abstract/PMC/5978417

10 July 2018

published in

Science

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28931639%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

volume

358

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14 June 2020

issue

6359

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14 June 2020

page(s)

85-90

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Early antibody therapy can induce long-lasting immunity to SHIV

14 June 2020

cites work

1 reference

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Identification and specificity of broadly neutralizing antibodies against HIV

15 July 2018

1 reference

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The HIV-1 envelope glycoprotein structure: nailing down a moving target

15 July 2018

1 reference

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Antibody gene transfer with adeno-associated viral vectors as a method for HIV prevention

15 July 2018

1 reference

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Use of broadly neutralizing antibodies for HIV-1 prevention

15 July 2018

1 reference

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The quest for an antibody-based HIV vaccine

15 July 2018

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HIV antibodies for treatment of HIV infection

15 July 2018

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Antibody 10-1074 suppresses viremia in HIV-1-infected individuals

15 July 2018

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Broadly Neutralizing Antibodies for HIV-1 Prevention or Immunotherapy

15 July 2018

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Effect of HIV Antibody VRC01 on Viral Rebound after Treatment Interruption

15 July 2018

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An HIV Vaccine: Mapping Uncharted Territory

15 July 2018

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HIV-1 antibody 3BNC117 suppresses viral rebound in humans during treatment interruption

15 July 2018

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Engineered Bispecific Antibodies with Exquisite HIV-1-Neutralizing Activity

15 July 2018

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Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency

15 July 2018

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HIV-1 therapy with monoclonal antibody 3BNC117 elicits host immune responses against HIV-1.

15 July 2018

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Broadly Neutralizing Antibodies to HIV and Their Role in Vaccine Design

15 July 2018

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Optimization of the Solubility of HIV-1-Neutralizing Antibody 10E8 through Somatic Variation and Structure-Based Design

15 July 2018

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CODV-Ig, a universal bispecific tetravalent and multifunctional immunoglobulin format for medical applications.

15 July 2018

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Virologic effects of broadly neutralizing antibody VRC01 administration during chronic HIV-1 infection

15 July 2018

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Human Immunodeficiency Virus Type 1 Monoclonal Antibodies Suppress Acute Simian-Human Immunodeficiency Virus Viremia and Limit Seeding of Cell-Associated Viral Reservoirs

15 July 2018

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Targeting HIV Reservoir in Infected CD4 T Cells by Dual-Affinity Re-targeting Molecules (DARTs) that Bind HIV Envelope and Recruit Cytotoxic T Cells

15 July 2018

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Activation and lysis of human CD4 cells latently infected with HIV-1

15 July 2018

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Viral variants that initiate and drive maturation of V1V2-directed HIV-1 broadly neutralizing antibodies

15 July 2018

1 reference

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Bispecific Antibodies Targeting Different Epitopes on the HIV-1 Envelope Exhibit Broad and Potent Neutralization.

15 July 2018

1 reference

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Maturation and Diversity of the VRC01-Antibody Lineage over 15 Years of Chronic HIV-1 Infection

15 July 2018

1 reference

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Sustained Delivery of a Broadly Neutralizing Antibody in Nonhuman Primates Confers Long-Term Protection against Simian/Human Immunodeficiency Virus Infection

15 July 2018

1 reference

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AAV-expressed eCD4-Ig provides durable protection from multiple SHIV challenges

15 July 2018

1 reference

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Improving neutralization potency and breadth by combining broadly reactive HIV-1 antibodies targeting major neutralization epitopes

15 July 2018

1 reference

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Recombinant HIV envelope trimer selects for quaternary-dependent antibodies targeting the trimer apex

15 July 2018

1 reference

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Enhanced neonatal Fc receptor function improves protection against primate SHIV infection

15 July 2018

1 reference

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Cooperation of B cell lineages in induction of HIV-1-broadly neutralizing antibodies

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5978417

Neutralizing antibodies to HIV-1 envelope protect more effectively in vivo than those to the CD4 receptor

15 July 2018

1 reference

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Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5978417

Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for HIV-1 Neutralization by VRC01-Class Antibodies

15 July 2018

1 reference

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HIV-1 neutralizing antibodies: understanding nature's pathways

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5978417

Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5978417

Multiple pathways of escape from HIV broadly cross-neutralizing V2-dependent antibodies

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5978417

Broad and potent neutralization of HIV-1 by a gp41-specific human antibody

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5978417

Human antibodies that neutralize HIV-1: identification, structures, and B cell ontogenies

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5978417

Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5978417

Rational design of envelope identifies broadly neutralizing human monoclonal antibodies to HIV-1

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5978417

Measuring HIV neutralization in a luciferase reporter gene assay

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5978417

Human immunodeficiency virus type 1 env clones from acute and early subtype B infections for standardized assessments of vaccine-elicited neutralizing antibodies

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5978417

Crystal structure of a neutralizing human IGG against HIV-1: a template for vaccine design

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5978417

An efficient route to human bispecific IgG.

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5978417

15 July 2018

Identifiers

DOI

10.1126/SCIENCE.AAN8630

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28931639%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28931639%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

PubMed publication ID

28931639

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28931639%20AND%20SRC:MED&resulttype=core&format=json