Roles of the N- and C-terminal domains of carnitine palmitoyltransferase I isoforms in malonyl-CoA sensitivity of the enzymes: insights from expression of chimaeric proteins and mutation of conserved histidine residues (Q41920104)

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scientific article published on November 1998

Language	Label	Description	Also known as
English	Roles of the N- and C-terminal domains of carnitine palmitoyltransferase I isoforms in malonyl-CoA sensitivity of the enzymes: insights from expression of chimaeric proteins and mutation of conserved histidine residues	scientific article published on November 1998

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

Roles of the N- and C-terminal domains of carnitine palmitoyltransferase I isoforms in malonyl-CoA sensitivity of the enzymes: insights from expression of chimaeric proteins and mutation of conserved histidine residues (English)

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

author name string

S T Swanson

1

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

D W Foster

2

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

J D McGarry

3

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

N F Brown

4

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

language of work or name

0 references

publication date

1 November 1998

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

Biochemical Journal

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

335 ( Pt 3)

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

513-519

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

Protein measurement with the Folin phenol reagent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219810

5 June 2018

Mouse white adipocytes and 3T3-L1 cells display an anomalous pattern of carnitine palmitoyltransferase (CPT) I isoform expression during differentiation: Inter-tissue and inter-species expression of CPT I and CPT II enzymes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219810

5 June 2018

Topology of carnitine palmitoyltransferase I in the mitochondrial outer membrane

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219810

5 June 2018

Functional characterization of mitochondrial carnitine palmitoyltransferases I and II expressed in the yeast Pichia pastoris

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219810

5 June 2018

The mitochondrial carnitine palmitoyltransferase system. From concept to molecular analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219810

5 June 2018

Isolation and characterization of cDNA and genomic clones encoding human muscle type carnitine palmitoyltransferase I.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219810

5 June 2018

Role of insulin in hepatic fatty acid partitioning: emerging concepts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219810

5 June 2018

Expression of a cDNA isolated from rat brown adipose tissue and heart identifies the product as the muscle isoform of carnitine palmitoyltransferase I (M-CPT I). M-CPT I is the predominant CPT I isoform expressed in both white (epididymal) and brown

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219810

5 June 2018

Cloning, sequencing, and expression of a cDNA encoding rat liver carnitine palmitoyltransferase I. Direct evidence that a single polypeptide is involved in inhibitor interaction and catalytic function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219810

5 June 2018

Expression of precursor and mature carnitine palmitoyltransferase II in Escherichia coli and in vitro: differential behaviour of rat and human isoforms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219810

5 June 2018

Rat heart expresses two forms of mitochondrial carnitine palmitoyltransferase I. The minor component is identical to the liver enzyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219810

5 June 2018

Human liver mitochondrial carnitine palmitoyltransferase I: characterization of its cDNA and chromosomal localization and partial analysis of the gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219810

5 June 2018

High expression of a novel carnitine palmitoyltransferase I like protein in rat brown adipose tissue and heart: isolation and characterization of its cDNA clone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219810

5 June 2018

Effect of pH on malonyl-CoA inhibition of carnitine palmitoyltransferase I.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219810

5 June 2018

Effects of pH on the interaction of substrates and malonyl-CoA with mitochondrial carnitine palmitoyltransferase I.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219810

5 June 2018

Observations on the affinity for carnitine, and malonyl-CoA sensitivity, of carnitine palmitoyltransferase I in animal and human tissues. Demonstration of the presence of malonyl-CoA in non-hepatic tissues of the rat

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219810

5 June 2018

Regulation of hepatic fatty acid oxidation and ketone body production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219810

5 June 2018

Malonyl-CoA binding site and the overt carnitine palmitoyltransferase activity reside on the opposite sides of the outer mitochondrial membrane

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219810

5 June 2018

Regulation of ketogenesis and the renaissance of carnitine palmitoyltransferase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219810

5 June 2018

Cloning, sequencing, and expression of a cDNA encoding rat liver mitochondrial carnitine palmitoyltransferase II

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219810

5 June 2018

Sensitivity of inhibition of rat liver mitochondrial outer-membrane carnitine palmitoyltransferase by malonyl-CoA to chemical- and temperature-induced changes in membrane fluidity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219810

5 June 2018

Rationale and application of fatty acid oxidation inhibitors in treatment of diabetes mellitus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219810

5 June 2018

Proteinase treatment of intact hepatic mitochondria has differential effects on inhibition of carnitine palmitoyltransferase by different inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219810

5 June 2018

Insights into the topography of mitochondrial carnitine palmitoyltransferase gained from the use of proteases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219810

5 June 2018

Reconstitution of Highly Expressed Human Heart Muscle Carnitine Palmitoyltransferase I

1 reference

https://pubmed.ncbi.nlm.nih.gov/9794789

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoglycemic effects of a novel fatty acid oxidation inhibitor in rats and monkeys

1 reference

https://pubmed.ncbi.nlm.nih.gov/9794789

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of the mitochondrial carnitine palmitoyltransferase enzyme system. II. Use of detergents and antibodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/9794789

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial import and processing of rat liver carnitine palmitoyltransferase II defines the amino terminus of the mature protein. Possibility of differential modification of the rat and human isoforms

1 reference

https://pubmed.ncbi.nlm.nih.gov/9794789

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mature carnitine palmitoyltransferase I retains the N-terminus of the nascent protein in rat liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/9794789

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hepatic carnitine palmitoyltransferase-I has two independent inhibitory binding sites for regulation of fatty acid oxidation

1 reference

https://pubmed.ncbi.nlm.nih.gov/9794789

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Catalytically important domains of rat carnitine palmitoyltransferase II as determined by site-directed mutagenesis and chemical modification. Evidence for a critical histidine residue

1 reference

https://pubmed.ncbi.nlm.nih.gov/9794789

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of a cDNA for rat liver carnitine palmitoyltransferase I in yeast establishes that catalytic activity and malonyl-CoA sensitivity reside in a single polypeptide

1 reference

https://pubmed.ncbi.nlm.nih.gov/9794789

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Use of a selective inhibitor of liver carnitine palmitoyltransferase I (CPT I) allows quantification of its contribution to total CPT I activity in rat heart. Evidence that the dominant cardiac CPT I isoform is identical to the skeletal muscle enzym

1 reference

https://pubmed.ncbi.nlm.nih.gov/9794789

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial carnitine palmitoyltransferase I isoform switching in the developing rat heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/9794789

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence that both the acyl-CoA- and malonyl-CoA binding sites of mitochondrial overt carnitine palmitoyltransferase (CPT I) are exposed on the cytosolic face of the outer membrane

1 reference

https://pubmed.ncbi.nlm.nih.gov/9794789

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1042/BJ3350513

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

ResearchGate publication ID

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