HPV16-E6 associated hTERT promoter acetylation is E6AP dependent, increased in later passage cells and enhanced by loss of p300. (Q41910482)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16708385%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

title

HPV16-E6 associated hTERT promoter acetylation is E6AP dependent, increased in later passage cells and enhanced by loss of p300 (English)

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21 January 2020

author

Aloysius J. Klingelhutz

series ordinal

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21 January 2020

Michael A James

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21 January 2020

John H Lee

series ordinal

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21 January 2020

language of work or name

English

0 references

publication date

1 October 2006

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International Journal of Cancer

21 January 2020

published in

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21 January 2020

volume

119

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21 January 2020

issue

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21 January 2020

page(s)

1878-1885

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Conditional telomerase induction causes proliferation of hair follicle stem cells

21 January 2020

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The E6AP ubiquitin ligase is required for transactivation of the hTERT promoter by the human papillomavirus E6 oncoprotein.

5 June 2018

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Identification of two distinct elements mediating activation of telomerase (hTERT) gene expression in association with cell growth in human T cells.

5 June 2018

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Identification of a novel telomerase repressor that interacts with the human papillomavirus type-16 E6/E6-AP complex

5 June 2018

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Small-molecule-based identification of dynamic assembly of E2F-pocket protein-histone deacetylase complex for telomerase regulation in human cells

5 June 2018

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Human papillomavirus type 16 E6 activates TERT gene transcription through induction of c-Myc and release of USF-mediated repression.

5 June 2018

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Human papillomavirus E6 and Myc proteins associate in vivo and bind to and cooperatively activate the telomerase reverse transcriptase promoter

5 June 2018

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The PDZ ligand domain of the human papillomavirus type 16 E6 protein is required for E6's induction of epithelial hyperplasia in vivo

5 June 2018

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Telomerase activation in cervical keratinocytes containing stably replicating human papillomavirus type 16 episomes.

5 June 2018

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Sp1 and Sp3 recruit histone deacetylase to repress transcription of human telomerase reverse transcriptase (hTERT) promoter in normal human somatic cells

5 June 2018

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Cervical epithelial cells transduced with the papillomavirus E6/E7 oncogenes maintain stable levels of oncoprotein expression but exhibit progressive, major increases in hTERT gene expression and telomerase activity

5 June 2018

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Telomerase activation by histone deacetylase inhibitor in normal cells

5 June 2018

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E box-dependent activation of telomerase by human papillomavirus type 16 E6 does not require induction of c-myc

5 June 2018

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Telomerase activation by human papillomavirus type 16 E6 protein: induction of human telomerase reverse transcriptase expression through Myc and GC-rich Sp1 binding sites

5 June 2018

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Antisense-mediated depletion of p300 in human cells leads to premature G1 exit and up-regulation of c-MYC.

5 June 2018

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Transcriptional activation of the telomerase hTERT gene by human papillomavirus type 16 E6 oncoprotein

5 June 2018

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Histone deacetylation is involved in the transcriptional repression of hTERT in normal human cells

5 June 2018

1 reference

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CBP/p300 histone acetyl-transferase activity is important for the G1/S transition

5 June 2018

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The human papillomavirus type 16 E6 oncoprotein can down-regulate p53 activity by targeting the transcriptional coactivator CBP/p300.

5 June 2018

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Telomerase activity in human development is regulated by human telomerase reverse transcriptase (hTERT) transcription and by alternate splicing of hTERT transcripts

5 June 2018

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DNA damage activates p53 through a phosphorylation-acetylation cascade

5 June 2018

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A comparative analysis of the interactions of the E6 proteins from cutaneous and genital papillomaviruses with p53 and E6AP in correlation to their transforming potential

5 June 2018

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Destabilization of the RB tumor suppressor protein and stabilization of p53 contribute to HPV type 16 E7-induced apoptosis

5 June 2018

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Telomerase activation by the E6 gene product of human papillomavirus type 16.

5 June 2018

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The ability of human papillomavirus E6 proteins to target p53 for degradation in vivo correlates with their ability to abrogate actinomycin D-induced growth arrest.

5 June 2018

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5 June 2018

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The histone deacetylase inhibitor trichostatin A derepresses the telomerase reverse transcriptase (hTERT) gene in human cells

18 August 2018

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Histone deacetylase inhibitors suppress telomerase reverse transcriptase mRNA expression in prostate cancer cells.

18 August 2018

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Regulation of activity of the transcription factor GATA-1 by acetylation

18 August 2018

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Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells.

18 August 2018

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18 August 2018

Identifiers

DOI

10.1002/IJC.22064

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16708385%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

1 reference

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21 January 2020

PubMed publication ID

16708385

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16708385%20AND%20SRC:MED&resulttype=core&format=json