Defining the roles of perforin, Fas/FasL, and tumour necrosis factor alpha in T cell induced mucosal damage in the mouse intestine (Q41824084)

12 October 2017

Defining the roles of perforin, Fas/FasL, and tumour necrosis factor alpha in T cell induced mucosal damage in the mouse intestine (English)

1 reference

12 October 2017

0 references

M Merger

1 reference

12 October 2017

J L Viney

1 reference

12 October 2017

R Borojevic

1 reference

12 October 2017

D Steele-Norwood

1 reference

12 October 2017

P Zhou

1 reference

12 October 2017

D A Clark

1 reference

12 October 2017

R Riddell

1 reference

12 October 2017

R Maric

1 reference

12 October 2017

E R Podack

1 reference

12 October 2017

K Croitoru

1 reference

12 October 2017

language of work or name

English

0 references

publication date

1 August 2002

1 reference

12 October 2017

1 reference

12 October 2017

1 reference

12 October 2017

1 reference

12 October 2017

155-163

1 reference

Lessons from genetically engineered animal models. VII. Apoptosis in intestinal epithelium: lessons from transgenic and knockout mice

12 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1773316

Stimulation of naïve and memory T cells by cytokines

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1773316

Fas activates the JNK pathway in human colonic epithelial cells: lack of a direct role in apoptosis

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1773316

Granzyme B mimics apical caspases. Description of a unified pathway for trans-activation of executioner caspase-3 and -7.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1773316

High Fas ligand expression on lymphocytes in lesions of ulcerative colitis

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1773316

T cell inactivation and cytokine deviation promoted by anti-CD3 mAbs

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1773316

Perforin/granzyme-dependent and independent mechanisms are both important for the development of graft-versus-host disease after murine bone marrow transplantation

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1773316

The role of granzyme B cluster proteases in cell-mediated cytotoxicity

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1773316

Increased small intestinal apoptosis in coeliac disease

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1773316

A major role for matrix metalloproteinases in T cell injury in the gut.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1773316

The role of cell-mediated cytotoxicity in acute GVHD after MHC-matched allogeneic bone marrow transplantation in mice

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1773316

Cytotoxic T cells deficient in both functional fas ligand and perforin show residual cytolytic activity yet lose their capacity to induce lethal acute graft-versus-host disease

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1773316

Analysis of enteropathy induced by tumour necrosis factor alpha.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1773316

Regional specialization of the mucosal immune system. Intraepithelial lymphocytes of the large intestine have a different phenotype and function than those of the small intestine.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1773316

Evidence that activated mucosal T cells play a role in the pathogenesis of enteropathy in human small intestine

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1773316

Identification of a monoclonal antibody specific for a murine T3 polypeptide

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1773316

Intestinal graft-versus-host disease is initiated by donor T cells distinct from classic cytotoxic T lymphocytes

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1773316

Capsaicin and primary afferent neurons: from basic science to human therapy?

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1773316

Cytolytic mechanisms of intraepithelial lymphocytes in coeliac disease (CoD).

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1773316

Mechanisms of intestinal epithelial cell injury and colitis in interleukin 2 (IL2)-deficient mice.

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1773316

Small bowel enteropathy: role of intraepithelial lymphocytes and of cytokines (IL-12, IFN-gamma, TNF) in the induction of epithelial cell death and renewal

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1773316

A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor alpha for Crohn's disease. Crohn's Disease cA2 Study Group.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1773316

Differential levels of granzyme B, regulatory cytokines, and apoptosis in Crohn's disease and ulcerative colitis at first presentation

18 August 2018

1 reference

12 December 2020

Effects of in vivo administration of anti-T3 monoclonal antibody on T cell function in mice. I. Immunosuppression of transplantation responses

1 reference

12 December 2020

The biology of the SCID mutation

1 reference

12 December 2020

Triggered human mucosal T cells release tumour necrosis factor-alpha and interferon-gamma which kill human colonic epithelial cells

1 reference

12 December 2020

T-cell activation can induce either mucosal destruction or adaptation in cultured human fetal small intestine

1 reference

12 December 2020

Phenotypic and functional assessment of intraepithelial lymphocytes bearing a 'forbidden' alpha beta TCR

1 reference

12 December 2020

Perforin, Fas ligand, and tumor necrosis factor are the major cytotoxic molecules used by lymphokine-activated killer cells

1 reference

12 December 2020

Cytotoxic effect of cytokines on murine colon carcinoma cells involves TNF-mediated apoptosis

1 reference

12 December 2020

Inhibition of graft-versus-host disease. Use of a T cell-controlled suicide gene

1 reference

12 December 2020

CD95 (APO-1/Fas)-mediated apoptosis in colon epithelial cells: a possible role in ulcerative colitis

1 reference

12 December 2020

Fas-mediated cytotoxicity by intestinal intraepithelial lymphocytes during acute graft-versus-host disease in mice

1 reference

12 December 2020

Mast cell involvement in gastritis with or without Helicobacter pylori infection

1 reference

12 December 2020

Perforin/Fas-ligand double deficiency is associated with macrophage expansion and severe pancreatitis

1 reference

12 December 2020

IL-17 is produced by some proinflammatory Th1/Th0 cells but not by Th2 cells

1 reference

12 December 2020

Tumor necrosis factor inhibitor ameliorates murine intestinal graft-versus-host disease

1 reference

12 December 2020

Therapeutic effect of an anti-Fas ligand mAb on lethal graft-versus-host disease

1 reference

12 December 2020

A p55 TNF receptor immunoadhesin prevents T cell-mediated intestinal injury by inhibiting matrix metalloproteinase production

1 reference

12 December 2020

Differential expression of Fas and Fas ligand in acute and chronic graft-versus-host disease: up-regulation of Fas and Fas ligand requires CD8+ T cell activation and IFN-gamma production

1 reference

12 December 2020

Consequences of Fas-ligand and perforin expression by colon T cells in a mouse model of inflammatory bowel disease

1 reference

12 December 2020

Identifiers

DOI

10.1136/GUT.51.2.155

1 reference

12 October 2017

1 reference

12 October 2017

PubMed publication ID

12117872

1 reference