Protein kinase C-mediated phosphorylation and activation of PDE3A regulate cAMP levels in human platelets. (Q41808295)

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22 January 2020

title

Protein kinase C-mediated phosphorylation and activation of PDE3A regulate cAMP levels in human platelets (English)

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22 January 2020

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22 January 2020

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22 January 2020

Ingeborg Hers

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22 January 2020

language of work or name

English

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publication date

4 March 2009

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Journal of Biological Chemistry

22 January 2020

published in

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22 January 2020

volume

284

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22 January 2020

issue

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22 January 2020

page(s)

12339-12348

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Phosphodiesterase 3 is present in rabbit and human erythrocytes and its inhibition potentiates iloprost-induced increases in cAMP

22 January 2020

cites work

1 reference

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Characterization of a protein kinase B inhibitor in vitro and in insulin-treated liver cells

6 June 2018

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Thrombin regulates intracellular cyclic AMP concentration in human platelets through phosphorylation/activation of phosphodiesterase 3A.

6 June 2018

1 reference

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Insulin-induced formation of macromolecular complexes involved in activation of cyclic nucleotide phosphodiesterase 3B (PDE3B) and its interaction with PKB.

6 June 2018

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Protein kinase B/Akt phosphorylation of PDE3A and its role in mammalian oocyte maturation

6 June 2018

1 reference

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Phosphodiesterase 3A binds to 14-3-3 proteins in response to PMA-induced phosphorylation of Ser428.

6 June 2018

1 reference

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Leptin-mediated activation of human platelets: involvement of a leptin receptor and phosphodiesterase 3A-containing cellular signaling complex

6 June 2018

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Dynamic interactions between 14-3-3 proteins and phosphoproteins regulate diverse cellular processes.

6 June 2018

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Scansite 2.0: Proteome-wide prediction of cell signaling interactions using short sequence motifs

6 June 2018

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Taming platelets with cyclic nucleotides

6 June 2018

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Membrane localization of cyclic nucleotide phosphodiesterase 3 (PDE3). Two N-terminal domains are required for the efficient targeting to, and association of, PDE3 with endoplasmic reticulum

6 June 2018

1 reference

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Cyclic nucleotides and phosphodiesterases in platelets

6 June 2018

1 reference

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Biphasic activation of PKBalpha/Akt in platelets. Evidence for stimulation both by phosphatidylinositol 3,4-bisphosphate, produced via a novel pathway, and by phosphatidylinositol 3,4,5-trisphosphate

6 June 2018

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Activation of cGMP-stimulated phosphodiesterase by nitroprusside limits cAMP accumulation in human platelets: effects on platelet aggregation

6 June 2018

1 reference

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Synergy between Ca2+ and protein kinase C is the major factor in determining the level of secretion from human platelets

6 June 2018

1 reference

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Multiple cyclic nucleotide phosphodiesterase activities from rat brain

6 June 2018

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Concentration and regulation of cyclic nucleotides, cyclic-nucleotide-dependent protein kinases and one of their major substrates in human platelets. Estimating the rate of cAMP-regulated and cGMP-regulated protein phosphorylation in intact cells

6 June 2018

1 reference

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Thrombin decreases platelet cyclic AMP in the absence of prostaglandin synthesis

6 June 2018

1 reference

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Control of platelet activation by cyclic AMP turnover and cyclic nucleotide phosphodiesterase type-3.

6 June 2018

1 reference

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Akt Activation in Platelets Depends on Gi Signaling Pathways

18 August 2018

1 reference

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Identification of the insulin-regulated interaction of phosphodiesterase 3B with 14-3-3 beta protein

18 August 2018

1 reference

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Differential regulation of human platelet responses by cGMP inhibited and stimulated cAMP phosphodiesterases

18 August 2018

1 reference

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Protease-activated receptors 1 and 4 do not stimulate G(i) signaling pathways in the absence of secreted ADP and cause human platelet aggregation independently of G(i) signaling

18 August 2018

1 reference

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Cyclic AMP-dependent phosphodiesterase isozyme-specific potentiation by protein kinase C in hypertrophic cardiomyopathic hamster hearts

18 August 2018

1 reference

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Regulation of platelet glycoprotein IIb/IIIa (integrin alpha IIB beta 3) function via the thrombin receptor

18 August 2018

1 reference

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Phosphorylation results in activation of a cAMP phosphodiesterase in human platelets

18 August 2018

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12 December 2020

Stimulation by Insulin of a Serine Kinase in Human Platelets That Phosphorylates and Activates the cGMP-Inhibited cAMP Phosphodiesterase

1 reference

12 December 2020

Single-step affinity purification, partial structure and properties of human platelet cGMP inhibited cAMP phosphodiesterase

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12 December 2020

Isolation and regulation of the cGMP-inhibited cAMP phosphodiesterase in human erythroleukemia cells

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12 December 2020

Differential involvement of tyrosine and serine/threonine kinases in platelet integrin alphaIIbbeta3 exposure

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12 December 2020

Role of phosphodiesterase type 3A and 3B in regulating platelet and cardiac function using subtype-selective knockout mice

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12 December 2020

Insulin-like growth factor-1 potentiates platelet activation via the IRS/PI3Kalpha pathway

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12 December 2020

The PKB inhibitor Akti-1/2 potentiates PAR-1-mediated platelet function independently of its ability to block PKB

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12 December 2020

Identifiers

DOI

10.1074/JBC.M807536200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19261611%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

1 reference

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22 January 2020

PubMed publication ID

19261611

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19261611%20AND%20SRC:MED&resulttype=core&format=json