The UNC-119 family of neural proteins is functionally conserved between humans, Drosophila and C. elegans. (Q41742120)

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7 November 2019

title

The UNC-119 family of neural proteins is functionally conserved between humans, Drosophila and C. elegans (English)

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7 November 2019

main subject

Caenorhabditis elegans

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Drosophila

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Unc-119 Dmel_CG1659

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GOA release 2020-03-11

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10858820%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

1 reference

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7 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10858820%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

M F Maduro

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7 November 2019

publication date

1 January 2000

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7 November 2019

published in

Journal of Neurogenetics

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7 November 2019

volume

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7 November 2019

issue

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7 November 2019

page(s)

191-212

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Anti-neural-inhibition: a conserved mechanism for neural induction

7 November 2019

cites work

1 reference

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The Caenorhabditis elegans gene unc-76 and its human homologs define a new gene family involved in axonal outgrowth and fasciculation

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UNC-40, a C. elegans homolog of DCC (Deleted in Colorectal Cancer), is required in motile cells responding to UNC-6 netrin cues

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Phenotype of mice lacking functional Deleted in colorectal cancer (Dcc) gene

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Collapsin-induced growth cone collapse mediated by an intracellular protein related to UNC-33

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The unc-5, unc-6, and unc-40 genes guide circumferential migrations of pioneer axons and mesodermal cells on the epidermis in C. elegans

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The DCC gene product in cellular differentiation and colorectal tumorigenesis

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UNC-6, a laminin-related protein, guides cell and pioneer axon migrations in C. elegans

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Deleted in Colorectal Cancer (DCC) encodes a netrin receptor

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Netrins are diffusible chemotropic factors for commissural axons in the embryonic spinal cord

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frazzled encodes a Drosophila member of the DCC immunoglobulin subfamily and is required for CNS and motor axon guidance.

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Mutations in a cyclic nucleotide-gated channel lead to abnormal thermosensation and chemosensation in C. elegans

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Rapid and efficient site-specific mutagenesis without phenotypic selection

21 January 2018

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Conservation of function and expression of unc-119 from two Caenorhabditis species despite divergence of non-coding DNA.

21 January 2018

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Dorsal-ventral patterning genes restrict NK-2 homeobox gene expression to the ventral half of the central nervous system of Drosophila embryos.

21 January 2018

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The netrins define a family of axon outgrowth-promoting proteins homologous to C. elegans UNC-6.

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Post-embryonic cell lineages of the nematode, Caenorhabditis elegans

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A non-radioactive in situ hybridization method for the localization of specific RNAs in Drosophila embryos reveals translational control of the segmentation gene hunchback

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21 January 2018

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Neuroglia and pioneer neurons express UNC-6 to provide global and local netrin cues for guiding migrations in C. elegans.

21 January 2018

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The Structure of the Nervous System of the Nematode Caenorhabditis elegans

21 January 2018

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