α-Synuclein strains cause distinct synucleinopathies after local and systemic administration (Q41681113)

7 October 2017

title

α-Synuclein strains cause distinct synucleinopathies after local and systemic administration (English)

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7 October 2017

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13 June 2020

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13 June 2020

W Peelaerts

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13 June 2020

L Bousset

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13 June 2020

A Van der Perren

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13 June 2020

R Pulizzi

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13 June 2020

C Van den Haute

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13 June 2020

R Melki

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13 June 2020

V Baekelandt

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13 June 2020

language of work or name

English

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publication date

10 June 2015

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7 October 2017

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26061766%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

volume

522

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13 June 2020

issue

7556

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13 June 2020

page(s)

340-344

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Cell-to-cell transmission of non-prion protein aggregates.

13 June 2020

cites work

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The propagation of prion-like protein inclusions in neurodegenerative diseases

21 January 2018

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Distinct α-synuclein strains differentially promote tau inclusions in neurons

21 January 2018

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Structural and functional characterization of two alpha-synuclein strains

21 January 2018

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Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation

21 January 2018

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Lewy body-like pathology in long-term embryonic nigral transplants in Parkinson's disease

21 January 2018

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Extracellular α--synuclein-a novel and crucial factor in Lewy body diseases.

21 January 2018

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Acceleration of oligomerization, not fibrillization, is a shared property of both alpha-synuclein mutations linked to early-onset Parkinson's disease: implications for pathogenesis and therapy

21 January 2018

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In vivo demonstration that alpha-synuclein oligomers are toxic

21 January 2018

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Fibrillar α-synuclein and huntingtin exon 1 assemblies are toxic to the cells

21 January 2018

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Pathological α-synuclein transmission initiates Parkinson-like neurodegeneration in nontransgenic mice

21 January 2018

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Induction of CNS α-synuclein pathology by fibrillar and non-amyloidogenic recombinant α-synuclein

21 January 2018

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Viral vector-mediated overexpression of α-synuclein as a progressive model of Parkinson's disease

21 January 2018

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Longitudinal follow-up and characterization of a robust rat model for Parkinson's disease based on overexpression of alpha-synuclein with adeno-associated viral vectors

21 January 2018

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Transfer of human α-synuclein from the olfactory bulb to interconnected brain regions in mice

21 January 2018

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Alpha-synuclein transfers from neurons to oligodendrocytes

21 January 2018

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Deficits in dopaminergic transmission precede neuron loss and dysfunction in a new Parkinson model

21 January 2018

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Lewy pathology is not the first sign of degeneration in vulnerable neurons in Parkinson disease

21 January 2018

1 reference

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Presynaptic alpha-synuclein aggregates, not Lewy bodies, cause neurodegeneration in dementia with Lewy bodies.

21 January 2018

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Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins

21 January 2018

1 reference

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αβγ-Synuclein triple knockout mice reveal age-dependent neuronal dysfunction

21 January 2018

1 reference

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Solution conditions determine the relative importance of nucleation and growth processes in α-synuclein aggregation

21 January 2018

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Prion-like transmission of protein aggregates in neurodegenerative diseases

21 January 2018

1 reference

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Prions and their lethal journey to the brain

21 January 2018

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Intramuscular injection of α-synuclein induces CNS α-synuclein pathology and a rapid-onset motor phenotype in transgenic mice.

21 January 2018

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Direct evidence of Parkinson pathology spread from the gastrointestinal tract to the brain in rats

21 January 2018

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Identification of protein interfaces between α-synuclein, the principal component of Lewy bodies in Parkinson disease, and the molecular chaperones human Hsc70 and the yeast Ssa1p.

21 January 2018

1 reference

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Efficient and stable transduction of dopaminergic neurons in rat substantia nigra by rAAV 2/1, 2/2, 2/5, 2/6.2, 2/7, 2/8 and 2/9.

21 January 2018

1 reference

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Selective insolubility of alpha-synuclein in human Lewy body diseases is recapitulated in a transgenic mouse model

21 January 2018

1 reference

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Intracerebral inoculation of pathological α-synuclein initiates a rapidly progressive neurodegenerative α-synucleinopathy in mice

21 January 2018

1 reference

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rAAV2/7 vector-mediated overexpression of alpha-synuclein in mouse substantia nigra induces protein aggregation and progressive dose-dependent neurodegeneration

21 January 2018

1 reference

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Characterization of lentiviral vector-mediated gene transfer in adult mouse brain

21 January 2018

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Design-based stereology in neuroscience

21 January 2018

1 reference

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Synaptic dynamics contribute to long-term single neuron response fluctuations

21 January 2018

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Command-line cellular electrophysiology for conventional and real-time closed-loop experiments

21 January 2018

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QSpike tools: a generic framework for parallel batch preprocessing of extracellular neuronal signals recorded by substrate microelectrode arrays

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1038/NATURE14547

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26061766%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

13 June 2020

1017998374

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26061766%20AND%20SRC:MED&resulttype=core&format=json