Molecular mechanisms of opiate and cocaine addiction (Q41652306)

6 October 2017

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title

Molecular mechanisms of opiate and cocaine addiction (English)

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6 October 2017

E. J. Nestler

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9384550

26 November 2024

language of work or name

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1 October 1997

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6 October 2017

October 1997

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National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=9384550

full work available at URL

26 November 2024

https://doi.org/10.1016/s0959-4388(97)80094-3

online access status

open access

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9384550

https://api.elsevier.com/content/article/PII:S0959438897800943?httpAccept=text/xml

26 November 2024

1 reference

DOI

https://api.crossref.org/works/10.1016/S0959-4388(97)80094-3

https://api.elsevier.com/content/article/PII:S0959438897800943?httpAccept=text/plain

26 November 2024

1 reference

DOI

https://api.crossref.org/works/10.1016/S0959-4388(97)80094-3

Current Opinion in Neurobiology

26 November 2024

published in

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6 October 2017

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6 October 2017

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6 October 2017

page(s)

713-719

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Neurobiology of addiction

6 October 2017

cites work

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7 January 2021

Drug addiction: the yin and yang of hedonic homeostasis

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7 January 2021

Dual regulation of adenylate cyclase accounts for narcotic dependence and tolerance

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7 January 2021

Drug addiction: a model for the molecular basis of neural plasticity.

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7 January 2021

Neural substrates of opiate withdrawal

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7 January 2021

Under siege: The brain on opiates

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7 January 2021

CREB (cAMP Response Element-Binding Protein) in the Locus Coeruleus: Biochemical, Physiological, and Behavioral Evidence for a Role in Opiate Dependence

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https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980094-3

7 January 2021

Elevated basal firing rates and enhanced responses to 8-Br-cAMP in locus coeruleus neurons in brain slices from opiate-dependent rats

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980094-3

7 January 2021

QX-314 blocks the potassium but not the sodium-dependent component of the opiate response in locus coeruleus neurons

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7 January 2021

A general role for adaptations in G-proteins and the cyclic AMP system in mediating the chronic actions of morphine and cocaine on neuronal function

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7 January 2021

Biochemical actions of chronic ethanol exposure in the mesolimbic dopamine system

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https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980094-3

7 January 2021

Chronic repeated cocaine administration increases dopamine D1 receptor-mediated signal transduction

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7 January 2021

The persistence of behavioral sensitization to cocaine parallels enhanced inhibition of nucleus accumbens neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980094-3

7 January 2021

Neuroadaptations in Nucleus Accumbens Neurons Resulting from Repeated Cocaine Administration

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https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980094-3

7 January 2021

Molecular Mechanisms of Drug Reinforcement and Addiction

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https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980094-3

7 January 2021

Hyperactivity and sensitization to psychostimulants following cholera toxin infusion into the nucleus accumbens.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980094-3

7 January 2021

Behavioral sensitization to cocaine: modulation by the cyclic AMP system in the nucleus accumbens

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980094-3

7 January 2021

A common mechanism mediates long-term changes in synaptic transmission after chronic cocaine and morphine

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980094-3

7 January 2021

Increased probability of GABA release during withdrawal from morphine

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980094-3

7 January 2021

Addiction to cocaine and amphetamine

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980094-3

7 January 2021

Regulation of kappa opioid receptor mRNA in the rat brain by "binge' pattern cocaine administration and correlation with preprodynorphin mRNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980094-3

7 January 2021

Molecular characterization of opioid receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980094-3

7 January 2021

Agonist-selective endocytosis of mu opioid receptor by neurons in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980094-3

7 January 2021

Phosphorylation and agonist-specific intracellular trafficking of an epitope-tagged mu-opioid receptor expressed in HEK 293 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980094-3

7 January 2021

Differential mu opiate receptor phosphorylation and desensitization induced by agonists and phorbol esters

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980094-3

7 January 2021

Chronic morphine administration increases beta-adrenergic receptor kinase (beta ARK) levels in the rat locus coeruleus

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980094-3

7 January 2021

Adaptive changes in the number of Gs- and Gi-proteins underlie adenylyl cyclase sensitization in morphine-treated rat striatal neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980094-3

7 January 2021

Effects of chronic morphine administration on mu opioid receptor-stimulated [35S]GTPgammaS autoradiography in rat brain

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980094-3

7 January 2021

Phosducin, potential role in modulation of olfactory signaling

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https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980094-3

7 January 2021

RGS proteins and signaling by heterotrimeric G proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980094-3

7 January 2021

Regulators of G-Protein Signaling (RGS) Proteins: Region-Specific Expression of Nine Subtypes in Rat Brain

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980094-3

7 January 2021

Agonist-induced desensitization of the mu opioid receptor-coupled potassium channel (GIRK1).

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980094-3

7 January 2021

Modulatory effects of Gs-coupled excitatory opioid receptor functions on opioid analgesia, tolerance, and dependence

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980094-3

7 January 2021

The stimulatory effects of opioids and their possible role in the development of tolerance.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980094-3

7 January 2021

Dopamine transmission in the initiation and expression of drug- and stress-induced sensitization of motor activity

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980094-3

7 January 2021

The neural basis of drug craving: an incentive-sensitization theory of addiction

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980094-3

7 January 2021

Relapse to heroin-seeking in rats under opioid maintenance: the effects of stress, heroin priming, and withdrawal

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980094-3

7 January 2021

Evidence for opiate-dopamine cross-sensitization in nucleus accumbens: studies of conditioned reward

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980094-3

7 January 2021

A comparison of the effects of intra-accumbens injections of amphetamine and morphine on reinstatement of heroin intravenous self-administration behavior

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980094-3

7 January 2021

Drugs of abuse and stress increase the expression of GluR1 and NMDAR1 glutamate receptor subunits in the rat ventral tegmental area: common adaptations among cross-sensitizing agents.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980094-3

7 January 2021

Sensitization to Morphine Induced by Viral-Mediated Gene Transfer

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980094-3

7 January 2021

Quantitation of dopamine transporter mRNA in the rat brain: mapping, effects of "binge" cocaine administration and withdrawal

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980094-3

7 January 2021

Reduction in dopamine transporter mRNA after cessation of repeated cocaine administration

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980094-3

7 January 2021

Cocaine uptake is decreased in the brain of detoxified cocaine abusers

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980094-3

7 January 2021

Euphorigenic doses of cocaine reduce [123I]beta-CIT SPECT measures of dopamine transporter availability in human cocaine addicts

1 reference

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7 January 2021

Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter

1 reference

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7 January 2021

Repeated amphetamine administration alters the expression of mRNA for AMPA receptor subunits in rat nucleus accumbens and prefrontal cortex

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980094-3

7 January 2021

5-Hydroxytryptamine1B receptors modulate the effect of cocaine on c-fos expression: converging evidence using 5-hydroxytryptamine1B knockout mice and the 5-hydroxytryptamine1B/1D antagonist GR127935.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980094-3

7 January 2021

Biological substrates of operant conditioning and the operant-respondent distinction

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980094-3

7 January 2021

Regulation of cyclic AMP response element-binding protein (CREB) phosphorylation by acute and chronic morphine in the rat locus coeruleus

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980094-3

7 January 2021

Regulation of expression of cAMP response element-binding protein in the locus coeruleus in vivo and in a locus coeruleus-like cell line in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980094-3

7 January 2021

Reduction of morphine abstinence in mice with a mutation in the gene encoding CREB.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980094-3

7 January 2021

Neuronal adaptation to amphetamine and dopamine: molecular mechanisms of prodynorphin gene regulation in rat striatum

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980094-3

7 January 2021

Induction of a long-lasting AP-1 complex composed of altered Fos-like proteins in brain by chronic cocaine and other chronic treatments.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980094-3

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980094-3

7 January 2021

Fos B mutant mice: Loss of chronic cocaine induction of Fos-related proteins and heightened sensitivity to cocaine’s psychomotor and rewarding effects

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980094-3

7 January 2021

Absence of a persistently elevated 37 kDa fos-related antigen and AP-1-like DNA-binding activity in the brains of kainic acid-treated fosB null mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980094-3

7 January 2021

NAC-1, a Rat Brain mRNA, Is Increased in the Nucleus Accumbens Three Weeks after Chronic Cocaine Self-Administration

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980094-3

7 January 2021

Activation of arc, a putative "effector" immediate early gene, by cocaine in rat brain.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980094-3

7 January 2021

Amphetamine increases the phosphorylation of neuromodulin and synapsin I in rat striatal synaptosomes

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980094-3

7 January 2021

Possible role for G-proteins in behavioral sensitization to cocaine

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980094-3

7 January 2021

Where is the locus in opioid withdrawal?

1 reference

https://api.crossref.org/works/10.1016/S0959-4388(97)80094-3

Evidence for involvement of ventral tegmental area cyclic AMP systems in behavioral sensitization to psychostimulants

26 November 2024

1 reference

https://api.crossref.org/works/10.1016/S0959-4388(97)80094-3

Desensitization of G protein-coupled receptors

26 November 2024

1 reference

https://api.crossref.org/works/10.1016/S0959-4388(97)80094-3

Agonist-dependent phosphorylation of the mouse delta-opioid receptor: involvement of G protein-coupled receptor kinases but not protein kinase C

26 November 2024

1 reference

https://api.crossref.org/works/10.1016/S0959-4388(97)80094-3

Regulation of CREB expression: in vivo evidence for a functional role in morphine action in the nucleus accumbens

26 November 2024

1 reference

https://api.crossref.org/works/10.1016/S0959-4388(97)80094-3

26 November 2024

Identifiers

DOI

1 reference

6 October 2017

1 reference