Cbl-mediated regulation of T cell receptor-induced AP1 activation. Implications for activation via the Ras signaling pathway (Q41655291)

6 October 2017

title

Cbl-mediated regulation of T cell receptor-induced AP1 activation. Implications for activation via the Ras signaling pathway (English)

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6 October 2017

B L Rellahan

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6 October 2017

L J Graham

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6 October 2017

B Stoica

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6 October 2017

K E DeBell

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6 October 2017

E Bonvini

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6 October 2017

language of work or name

English

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publication date

1 December 1997

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Journal of Biological Chemistry

6 October 2017

published in

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6 October 2017

volume

272

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6 October 2017

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6 October 2017

page(s)

30806-30811

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Regulation of lymphocyte function by protein phosphorylation

6 October 2017

cites work

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Delineation of a T-cell activation motif required for binding of protein tyrosine kinases containing tandem SH2 domains

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Functional characterization of a signal transducing motif present in the T cell antigen receptor zeta chain

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Inhibition of tyrosine phosphorylation prevents T-cell receptor-mediated signal transduction

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T cell antigen receptor-mediated activation of phospholipase C requires tyrosine phosphorylation

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c-Fos transcriptional activity stimulated by H-Ras-activated protein kinase distinct from JNK and ERK.

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How MAP kinases are regulated

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The protein product of the c-cbl protooncogene is phosphorylated after B cell receptor stimulation and binds the SH3 domain of Bruton's tyrosine kinase

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p120cbl is a major substrate of tyrosine phosphorylation upon B cell antigen receptor stimulation and interacts in vivo with Fyn and Syk tyrosine kinases, Grb2 and Shc adaptors, and the p85 subunit of phosphatidylinositol 3-kinase

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The proto-oncogene product c-Cbl becomes tyrosine phosphorylated by stimulation with GM-CSF or Epo and constitutively binds to the SH3 domain of Grb2/Ash in human hematopoietic cells

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TPO/c-mpl ligand induces tyrosine phosphorylation of multiple cellular proteins including proto-oncogene products, Vav and c-Cbl, and Ras signaling molecules

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Coupling of the Proto-oncogene Product c-Cbl to the Epidermal Growth Factor Receptor

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Interactions of Cbl with two adapter proteins, Grb2 and Crk, upon T cell activation

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Interactions of Cbl with Grb2 and phosphatidylinositol 3'-kinase in activated Jurkat cells

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The product of the cbl oncogene forms stable complexes in vivo with endogenous Crk in a tyrosine phosphorylation-dependent manner

21 January 2018

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Association of tyrosine protein kinase Zap-70 with the protooncogene product p120c-cbl in T lymphocytes

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A novel phosphotyrosine-binding domain in the N-terminal transforming region of Cbl interacts directly and selectively with ZAP-70 in T cells

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21 January 2018

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21 January 2018

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Differentiation of 3T3-L1 fibroblasts to adipocytes induced by transfection of ras oncogenes

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Transcriptional regulation of the T cell antigen receptor zeta subunit: identification of a tissue-restricted promoter

21 January 2018

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p21ras couples the T cell antigen receptor to extracellular signal-regulated kinase 2 in T lymphocytes.

21 January 2018

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Direct stimulation of Vav guanine nucleotide exchange activity for Ras by phorbol esters and diglycerides

21 January 2018

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Activation of human peripheral blood T lymphocytes by pharmacological induction of protein-tyrosine phosphorylation

21 January 2018

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The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the Ras activator mSos1

21 January 2018

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Ligation of the T-cell Antigen Receptor (TCR) Induces Association of hSos1, ZAP-70, Phospolipase C- 1, and Other Phosphoproteins with Grb2 and the -Chain of the TCR

21 January 2018

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Interaction of Shc with Grb2 regulates association of Grb2 with mSOS

21 January 2018

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Phosphorylation of transcription factor p62TCF by MAP kinase stimulates ternary complex formation at c-fos promoter

21 January 2018

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The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain

21 January 2018

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Molecular glue: kinase anchoring and scaffold proteins

21 January 2018

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Crk interacts with tyrosine-phosphorylated p116 upon T cell activation

21 January 2018

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Interactions between Src homology (SH) 2/SH3 adapter proteins and the guanylnucleotide exchange factor SOS are differentially regulated by insulin and epidermal growth factor

21 January 2018

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Antisense repression of proto-oncogene c-Cbl enhances activation of the JAK-STAT pathway but not the ras pathway in epidermal growth factor receptor signaling

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.272.49.30806

1 reference

6 October 2017

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