Low absolute mutagenic efficiency but high cytotoxicity of a non-bay region diol epoxide derived from benzo[a]pyrene (Q41655132)

6 October 2017

title

Low absolute mutagenic efficiency but high cytotoxicity of a non-bay region diol epoxide derived from benzo[a]pyrene (English)

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8 November 2022

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8 November 2022

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8 November 2022

MacLeod MC

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6 October 2017

M. C. MacLeod

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8 November 2022

G. Adair

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8 November 2022

A. Daylong

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8 November 2022

L. Lew

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8 November 2022

R. M. Humphrey

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8 November 2022

language of work or name

English

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publication date

1 December 1991

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full work available at URL

6 October 2017

https://api.elsevier.com/content/article/PII:016512189190043L?httpAccept=text/xml

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https://api.elsevier.com/content/article/PII:016512189190043L?httpAccept=text/plain

8 November 2022

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8 November 2022

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6 October 2017

volume

261

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6 October 2017

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6 October 2017

page(s)

281-293

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Induction and expression of mutations at multiple drug-resistance marker loci in Chinese hamster ovary cells.

6 October 2017

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Targeted homologous recombination at the endogenous adenine phosphoribosyltransferase locus in Chinese hamster cells

8 November 2022

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The action of oncogenes and growth factors in tumour initiation and promotion

8 November 2022

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Mutagenesis of the Ha-ras oncogene in mouse skin tumors induced by polycyclic aromatic hydrocarbons

8 November 2022

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DNA repair in an active gene: removal of pyrimidine dimers from the DHFR gene of CHO cells is much more efficient than in the genome overall.

8 November 2022

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Survival of UV-irradiated mammalian cells correlates with efficient DNA repair in an essential gene

8 November 2022

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High-resolution mapping of carcinogen binding sites on DNA

8 November 2022

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Summary of complementation groups of UV-sensitive CHO cell mutants isolated by large-scale screening

8 November 2022

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Applied Multiple Regression/Correlation Analysis for the Behavioral Sciences

8 November 2022

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Electric linear dichroism study on the orientation of benzo[a]pyrene-7,8-dihydrodiol 9,10-oxide covalently bound to DNA

8 November 2022

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Preferred sites of strand scission in DNA modified by andi-diol epoxide of benzo[a]pyrene

8 November 2022

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Structures of benzo(a)pyrene–nucleic acid adducts formed in human and bovine bronchial explants

8 November 2022

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Preferential modification of GC boxes by benzo[a]pyrene-7,8-diol-9,10-epoxide

8 November 2022

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The effect of neighbouring bases on G-specific DNA cleavage mediated by treatment with the anti-diol epoxide of benzo[a]pyrene in vitro.

8 November 2022

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Physical interactions of isomeric benzo [a] pyrene diol-epoxides with DNA.

8 November 2022

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Covalent binding of isomeric benzo[a]pyrene diol-epoxides to DNA.

8 November 2022

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Stabilization of a reactive, electrophilic carcinogen, benzo[a]pyrene diol epoxide, by mammalian cells

8 November 2022

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Differential efficiency of mutagenesis at three genetic loci in CHO cells by a benzo[a]pyrene diol epoxide

8 November 2022

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Differences in the rate of DNA adduct removal and the efficiency of mutagenesis for two benzo[a]pyrene diol epoxides in CHO cells

8 November 2022

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Differential DNA repair in transcriptionally active and inactive proto-oncogenes: c-abl and c-mos

8 November 2022

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Malignant transformation and mutagenesis in mammalian cells induced by vicinal diol-epoxides derived from benzo(a)pyrene.

8 November 2022

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Effects of pH and salt concentration on the hydrolysis of a benzo[alpha]pyrene 7,8-diol-9,10-epoxide catalyzed by DNA and polyadenylic acid.

8 November 2022

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Searches for ultimate chemical carcinogens and their reactions with cellular macromolecules.

8 November 2022

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Repair of (6-4)photoproducts correlates with split-dose recovery in UV-irradiated normal and hypersensitive rodent cells

8 November 2022

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Characterization of DNA adducts derived from (+/- )-trans-3,4-dihydroxy-anti-1,2-epoxy-1,2,3,4- tetrahydrodibenz[a,j]anthracene and (+/- )-7-methyl-trans-3,4-dihydroxy- anti-1,2-epoxy-1,2,3,4-tetrahydrodibenz[a,j]anthracene

8 November 2022

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Sequence selectivity in the reaction of optically active hydrocarbon dihydrodiol epoxides with rat H-ras DNA

8 November 2022

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Skin-tumor-initiating ability of benzo(a)pyrene-7,8-diol-9,10-epoxide (anti) when applied topically in tetrahydrofuran

8 November 2022

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Frequency of intrachromosomal homologous recombination induced by UV radiation in normally repairing and excision repair-deficient human cells

8 November 2022

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Carcinogens can induce homologous recombination between duplicated chromosomal sequences in mouse L cells

8 November 2022

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Current concepts and controversies in chemical carcinogenesis

8 November 2022

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8 November 2022

Identifiers

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6 October 2017

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