Upregulation of dopamine D2 receptors in the nucleus accumbens indirect pathway increases locomotion but does not reduce alcohol consumption. (Q41595563)

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scientific article published on 12 January 2015

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English	Upregulation of dopamine D2 receptors in the nucleus accumbens indirect pathway increases locomotion but does not reduce alcohol consumption.	scientific article published on 12 January 2015

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27 February 2020

Upregulation of dopamine D2 receptors in the nucleus accumbens indirect pathway increases locomotion but does not reduce alcohol consumption (English)

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27 February 2020

alcohol consumption

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nucleus accumbens

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Jonathan Javitch

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27 February 2020

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Eduardo F Gallo

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27 February 2020

Michael C Salling

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27 February 2020

Bo Feng

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27 February 2020

Jose A Morón

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Neil L Harrison

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27 February 2020

Christoph Kellendonk

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12 January 2015

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27 February 2020

Neuropsychopharmacology

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27 February 2020

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27 February 2020

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27 February 2020

1609-1618

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27 February 2020

Evidence against dopamine D1/D2 receptor heteromers

1 reference

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Dopamine D2 receptors regulate the anatomical and functional balance of basal ganglia circuitry.

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Increasing dopamine D2 receptor expression in the adult nucleus accumbens enhances motivation

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Strengthening the accumbal indirect pathway promotes resilience to compulsive cocaine use.

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Concurrent activation of striatal direct and indirect pathways during action initiation.

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Transient neuronal inhibition reveals opposing roles of indirect and direct pathways in sensitization

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Cell type-specific loss of BDNF signaling mimics optogenetic control of cocaine reward

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Distinct roles of synaptic transmission in direct and indirect striatal pathways to reward and aversive behavior

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Regulation of parkinsonian motor behaviours by optogenetic control of basal ganglia circuitry

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Hybrid mice as genetic models of high alcohol consumption

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Drd2 expression in the high alcohol-preferring and low alcohol-preferring mice

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Perception of sweet taste is important for voluntary alcohol consumption in mice.

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Nucleus accumbens D2/3 receptors predict trait impulsivity and cocaine reinforcement

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Dopamine D2R DNA transfer in dopamine D2 receptor-deficient mice: effects on ethanol drinking

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Psychomotor-activating effects mediated by dopamine D(2) and D(3) receptors in the nucleus accumbens

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Modulation of locomotor activity by NMDA receptors in the nucleus accumbens core and shell regions of the rat.

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Microinjection of sulpiride into the nucleus accumbens increases ethanol drinking in alcohol-preferring (P) rats

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Oral ethanol self-administration in rats is reduced by the administration of dopamine and glutamate receptor antagonists into the nucleus accumbens

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Alcohol-preferring rats have fewer dopamine D2 receptors in the limbic system

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Striatal dopamine release is triggered by synchronized activity in cholinergic interneurons

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High levels of dopamine D2 receptors in unaffected members of alcoholic families: possible protective factors

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DRD2 gene transfer into the nucleus accumbens core of the alcohol preferring and nonpreferring rats attenuates alcohol drinking

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Effects of selective dopamine D1 or D2 receptor blockade within nucleus accumbens subregions on ingestive behavior and associated motor activity

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Social dominance in monkeys: dopamine D2 receptors and cocaine self-administration

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Overexpression of dopamine D2 receptors reduces alcohol self-administration

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Alcohol preference and sensitivity are markedly reduced in mice lacking dopamine D2 receptors.

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Differential Behavioral Responses to Dopaminergic Stimulation of Nucleus Accumbens Subregions in the Rat

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Alcohol self-administration: further examination of the role of dopamine receptors in the nucleus accumbens.

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Effect of dopamine agonists and antagonists on ethanol-reinforced behavior: the involvement of the nucleus accumbens.

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Motor impairment in Alzheimer's disease and transgenic Alzheimer's disease mouse models.

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Striatal D2 dopamine receptor binding characteristics in vivo in patients with alcohol dependence

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31 March 2020

Densities of dopamine D2 receptors are reduced in CNS regions of alcohol-preferring P rats

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Dopamine receptor agonist reduces ethanol self-administration in the ethanol-preferring C57BL/6J inbred mouse

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31 March 2020

ALCOHOL TASTE THRESHOLDS AND CONCENTRATIONS OF SOLUTION PREFERRED BY RATS

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10.1038/NPP.2015.11

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27 February 2020

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27 February 2020

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