The SARS-coronavirus nsp7+nsp8 complex is a unique multimeric RNA polymerase capable of both de novo initiation and primer extension (Q41578444)

4 October 2017

The SARS-coronavirus nsp7+nsp8 complex is a unique multimeric RNA polymerase capable of both de novo initiation and primer extension (English)

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non-structural protein 7 [SARS-Cov]

4 October 2017

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non-structural protein 8 [SARS-Cov]

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Eric J Snijder

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Aartjan J W te Velthuis

series ordinal

object named as

Aartjan J W te Velthuis

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4 October 2017

Sjoerd H E van den Worm

series ordinal

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4 October 2017

29 October 2011

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4 October 2017

Nucleic Acids Research

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4 October 2017

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4 October 2017

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4 October 2017

1737-1747

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PMC publication ID

3287201

Creative Commons Attribution-NonCommercial 3.0 Unported

4 October 2017

start time

7 November 2016

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April 2022 Public Data File from Crossref

copyrighted

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describes a project that uses

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3287201/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Zn(2+) inhibits coronavirus and arterivirus RNA polymerase activity in vitro and zinc ionophores block the replication of these viruses in cell culture

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In vitro reconstitution of SARS-coronavirus mRNA cap methylation

6 June 2018

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The RNA polymerase activity of SARS-coronavirus nsp12 is primer dependent

6 June 2018

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Coronaviruses post-SARS: update on replication and pathogenesis

6 June 2018

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A noncovalent class of papain-like protease/deubiquitinase inhibitors blocks SARS virus replication

6 June 2018

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Genome-wide analysis of protein-protein interactions and involvement of viral proteins in SARS-CoV replication

6 June 2018

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SARS-coronavirus replication/transcription complexes are membrane-protected and need a host factor for activity in vitro

6 June 2018

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The SARS-Coronavirus PLnc domain of nsp3 as a replication/transcription scaffolding protein

6 June 2018

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Ovarian tumor domain-containing viral proteases evade ubiquitin- and ISG15-dependent innate immune responses

6 June 2018

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Genetic interactions between an essential 3' cis-acting RNA pseudoknot, replicase gene products, and the extreme 3' end of the mouse coronavirus genome

6 June 2018

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Two proton transfers in the transition state for nucleotidyl transfer catalyzed by RNA- and DNA-dependent RNA and DNA polymerases

6 June 2018

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Crystal Structure of Poliovirus 3CD Protein: Virally Encoded Protease and Precursor to the RNA-Dependent RNA Polymerase

6 June 2018

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The coronavirus replicase: insights into a sophisticated enzyme machinery

6 June 2018

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A second, non-canonical RNA-dependent RNA polymerase in SARS Coronavirus

6 June 2018

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Nidovirus transcription: how to make sense...?

6 June 2018

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Mechanisms of action of ribavirin against distinct viruses

6 June 2018

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Insights into SARS-CoV transcription and replication from the structure of the nsp7-nsp8 hexadecamer

6 June 2018

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Origin and evolution of the archaeo-eukaryotic primase superfamily and related palm-domain proteins: structural insights and new members

6 June 2018

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Ribavirin and interferon-beta synergistically inhibit SARS-associated coronavirus replication in animal and human cell lines.

6 June 2018

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Structural basis for proteolysis-dependent activation of the poliovirus RNA-dependent RNA polymerase

6 June 2018

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Multiple enzymatic activities associated with severe acute respiratory syndrome coronavirus helicase

6 June 2018

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MUSCLE: multiple sequence alignment with high accuracy and high throughput

6 June 2018

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6 June 2018

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Molecular model of SARS coronavirus polymerase: implications for biochemical functions and drug design

6 June 2018

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Unique and conserved features of genome and proteome of SARS-coronavirus, an early split-off from the coronavirus group 2 lineage

6 June 2018

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Host Factors in Positive-Strand RNA Virus Genome Replication

6 June 2018

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Synthesis of subgenomic RNAs by positive-strand RNA viruses

6 June 2018

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Virus-encoded proteinases and proteolytic processing in the Nidovirales.

6 June 2018

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Mutation of the aspartic acid residues of the GDD sequence motif of poliovirus RNA-dependent RNA polymerase results in enzymes with altered metal ion requirements for activity

6 June 2018

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Fidelity of DNA synthesis catalyzed by human DNA polymerase alpha and HIV-1 reverse transcriptase: effect of reaction pH

6 June 2018

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Coronavirus genome: prediction of putative functional domains in the non-structural polyprotein by comparative amino acid sequence analysis.

6 June 2018

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Processing of open reading frame 1a replicase proteins nsp7 to nsp10 in murine hepatitis virus strain A59 replication

6 June 2018

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A new lead for nonpeptidic active-site-directed inhibitors of the severe acute respiratory syndrome coronavirus main protease discovered by a combination of screening and docking methods

19 August 2018

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Inhibitory effect of mizoribine and ribavirin on the replication of severe acute respiratory syndrome (SARS)-associated coronavirus

19 August 2018

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The broad-spectrum antiviral ribonucleoside ribavirin is an RNA virus mutagen

19 August 2018

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Production of "authentic" poliovirus RNA-dependent RNA polymerase (3D(pol)) by ubiquitin-protease-mediated cleavage in Escherichia coli.

19 August 2018

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Poliovirus RNA-dependent RNA polymerase (3Dpol) is sufficient for template switching in vitro

19 August 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/22039154

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/NAR/GKR893

1 reference

4 October 2017

1 reference

PMC publication ID

3287201

4 October 2017

PubMed publication ID

22039154

1 reference

PMC publication ID

3287201