Sialidases: structures, biological significance and therapeutic potential (Q41312658)

29 September 2017

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title

Sialidases: structures, biological significance and therapeutic potential (English)

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29 September 2017

Taylor G

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29 September 2017

publication date

1 December 1996

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Current Opinion in Structural Biology

29 September 2017

published in

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29 September 2017

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29 September 2017

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29 September 2017

page(s)

830-837

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Sialic acids as important molecules in the regulation of the immune system: pathophysiological implications of sialidases in immunity

29 September 2017

cites work

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7 January 2021

Flow cytofluorimetric analysis of young and senescent human erythrocytes probed with lectins. Evidence that sialic acids control their life span

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7 January 2021

Diversity in the sialic acids

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7 January 2021

A single amino acid changes enhances the fusion promotion activity of human parainfluenza virus type 1 hemagglutinin-neuraminidase glycoprotein

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7 January 2021

Identification of regions on the hemagglutinin-neuraminidase protein of human parainfluenza virus type 2 important for promoting cell fusion

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7 January 2021

Structural requirements in the membrane-spanning domain of the paramyxovirus HN protein for the formation of a stable tetramer

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7 January 2021

Sequence and structure alignment of paramyxovirus hemagglutinin-neuraminidase with influenza virus neuraminidase.

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7 January 2021

Bacterial sialidases--roles in pathogenicity and nutrition

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7 January 2021

Role of Vibrio cholerae neuraminidase in the function of cholera toxin

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7 January 2021

The production of neuraminidase and fucosidase by Helicobacter pylori: their possible relationship to pathogenicity

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7 January 2021

Diversity in the properties of two sialidase isoenzymes produced by Clostridium perfringens spp

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7 January 2021

Conserved sequences in bacterial and viral sialidases

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7 January 2021

Trypanosoma cruzi trans-sialidase and cell invasion

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7 January 2021

Purification and characterization of a novel sialidase found in procyclic culture forms of Trypanosoma brucei

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7 January 2021

Mediation of Trypanosoma cruzi invasion by sialic acid on the host cell and trans-sialidase on the trypanosome

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7 January 2021

The Trypanosoma cruzi neuraminidase contains sequences similar to bacterial neuraminidases, YWTD repeats of the low density lipoprotein receptor, and type III modules of fibronectin

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7 January 2021

Substrate specificity of the Trypanosoma cruzi trans-sialidase

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7 January 2021

Trypanosoma cruzi trans-sialidase: enhancement of virulence in a murine model of Chagas' disease

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7 January 2021

Distribution of developmentally regulated trans-sialidases in the Kinetoplastida and characterization of a shed trans-sialidase activity from procyclic Trypanosoma congolense

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7 January 2021

Plasmodium falciparum lacks sialidase and trans-sialidase activity

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7 January 2021

Complete nucleotide sequence of the gene encoding bacteriophage E endosialidase: implications for K1E endosialidase structure and function

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7 January 2021

Complete nucleotide sequence of the bacteriophage K1F tail gene encoding endo-N-acylneuraminidase (endo-N) and comparison to an endo-N homolog in bacteriophage PK1E.

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7 January 2021

Structure of the influenza virus glycoprotein antigen neuraminidase at 2.9 A resolution

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7 January 2021

Influenza virus neuraminidase: structure, antibodies, and inhibitors

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7 January 2021

Crystal structure of a bacterial sialidase (from Salmonella typhimurium LT2) shows the same fold as an influenza virus neuraminidase

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7 January 2021

Crystal structure of Vibrio cholerae neuraminidase reveals dual lectin-like domains in addition to the catalytic domain

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7 January 2021

The three domains of a bacterial sialidase: a beta-propeller, an immunoglobulin module and a galactose-binding jelly-roll

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7 January 2021

Repeat sequences in the Bordetella pertussis adenylate cyclase toxin can be recognized as alternative carboxy-proximal secretion signals by the Escherichia coli alpha-haemolysin translocator.

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7 January 2021

A single tyrosine differentiates active and inactive Trypanosoma cruzi trans-sialidases.

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7 January 2021

Rational design of potent sialidase-based inhibitors of influenza virus replication

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7 January 2021

4-Guanidino-2,4-dideoxy-2,3-dehydro-N-acetylneuraminic acid is a highly effective inhibitor both of the sialidase (neuraminidase) and of growth of a wide range of influenza A and B viruses in vitro

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7 January 2021

Inhibition of replication of avian influenza viruses by the neuraminidase inhibitor 4-guanidino-2,4-dideoxy-2,3-dehydro-N-acetylneuraminic acid

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7 January 2021

4-Guanidino-Neu5Ac2en fails to protect chickens from infection with highly pathogenic avian influenza virus

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7 January 2021

Three-dimensional structure of the complex of 4-guanidino-Neu5Ac2en and influenza virus neuraminidase

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7 January 2021

A study of the active site of influenza virus sialidase: an approach to the rational design of novel anti-influenza drugs

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7 January 2021

Structure-based inhibitors of influenza virus sialidase. A benzoic acid lead with novel interaction

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7 January 2021

Benzoic acid inhibitors of influenza virus neuraminidase

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7 January 2021

A strategy for theoretical binding constant, Ki, calculations for neuraminidase aromatic inhibitors designed on the basis of the active site structure of influenza virus neuraminidase.

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7 January 2021

Generation and characterization of an influenza virus neuraminidase variant with decreased sensitivity to the neuraminidase-specific inhibitor 4-guanidino-Neu5Ac2en

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7 January 2021

Molecular basis for the resistance of influenza viruses to 4-guanidino-Neu5Ac2en

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7 January 2021

Towards the synthesis of sialic acid-based Salmonella typhimurium sialidase inhibitors

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7 January 2021

The structures of Salmonella typhimurium LT2 neuraminidase and its complexes with three inhibitors at high resolution

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7 January 2021

A sialic acid-derived phosphonate analog inhibits different strains of influenza virus neuraminidase with different efficiencies

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7 January 2021

10.1016/S0959-440X(96)80014-5

Identifiers

DOI

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29 September 2017

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