MicroRNA-153 targeting of KCNQ4 contributes to vascular dysfunction in hypertension (Q41166517)

27 September 2017

MicroRNA-153 targeting of KCNQ4 contributes to vascular dysfunction in hypertension (English)

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regulation of artery morphogenesis

27 September 2017

1 reference

positive regulation of artery morphogenesis

GO:1905651

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regulation of artery smooth muscle contraction

GO:1905653

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relaxation of vascular associated smooth muscle

GO:1905654

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negative regulation of artery morphogenesis

GO:0060087

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negative regulation of artery smooth muscle contraction

GO:1905652

1 reference

positive regulation of artery smooth muscle contraction

GO:1905655

1 reference

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27389411%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27389411%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27389411%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27389411%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Georgina Carr

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27389411%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Vincenzo Barrese

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27389411%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Hericka B Figueiredo

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27389411%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Dongling Zheng

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27389411%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Oleksandr V Povstyan

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27389411%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

publication date

7 July 2016

1 reference

27 September 2017

Cardiovascular Research

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27389411%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

volume

112

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10 June 2020

issue

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10 June 2020

page(s)

581-589

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27389411%20AND%20SRC:MED&resulttype=core&format=json

G-protein βγ subunits are positive regulators of Kv7.4 and native vascular Kv7 channel activity.

10 June 2020

cites work

1 reference

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Vasorelaxant effects of novel Kv 7.4 channel enhancers ML213 and NS15370

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079273

Emerging role of microRNAs in cardiovascular diseases.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079273

MicroRNA-133a regulates insulin-like growth factor-1 receptor expression and vascular smooth muscle cell proliferation in murine atherosclerosis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079273

Expression of microRNAs is essential for arterial myogenic tone and pressure-induced activation of the PI3-kinase/Akt pathway.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079273

Downregulation of miR-223 and miR-153 mediates mechanical stretch-stimulated proliferation of venous smooth muscle cells via activation of the insulin-like growth factor-1 receptor

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079273

MicroRNA-153 negatively regulates the expression of amyloid precursor protein and amyloid precursor-like protein 2.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079273

MicroRNA regulation of smooth muscle gene expression and phenotype

27 September 2017

1 reference

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Pharmacological dissection of K(v)7.1 channels in systemic and pulmonary arteries

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079273

Small artery remodelling in hypertension.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079273

Smooth muscle miRNAs are critical for post-natal regulation of blood pressure and vascular function

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079273

Vasodilator signals from perivascular adipose tissue

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079273

Activation of vascular KCNQ (Kv7) potassium channels reverses spasmogen-induced constrictor responses in rat basilar artery.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079273

Deregulation of miR-519a, 153, and 485-5p and its clinicopathological relevance in ovarian epithelial tumours

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079273

Expression and function of the K+ channel KCNQ genes in human arteries.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079273

The widespread regulation of microRNA biogenesis, function and decay

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079273

MicroRNAs are necessary for vascular smooth muscle growth, differentiation, and function

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079273

Post-transcriptional regulation of alpha-synuclein expression by mir-7 and mir-153

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079273

Origins and Mechanisms of miRNAs and siRNAs

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079273

MicroRNAs: target recognition and regulatory functions

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079273

Small-molecule inhibitors of microrna miR-21 function

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079273

Vascular KCNQ potassium channels as novel targets for the control of mesenteric artery constriction by vasopressin, based on studies in single cells, pressurized arteries, and in vivo measurements of mesenteric vascular resistance.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079273

MicroRNA sponges: competitive inhibitors of small RNAs in mammalian cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079273

Projections of global mortality and burden of disease from 2002 to 2030

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079273

Silencing of microRNAs in vivo with 'antagomirs'

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079273

Electrophysiological and functional effects of the KCNQ channel blocker XE991 on murine portal vein smooth muscle cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079273

Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079273

The functions of animal microRNAs

27 September 2017

1 reference

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Molecular regulation of vascular smooth muscle cell differentiation in development and disease

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079273

Vascular remodelling of resistance vessels: can we define this?

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079273

Evaluation of medial hypertrophy in resistance vessels of spontaneously hypertensive rats

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079273

Migration of smooth muscle and endothelial cells. Critical events in restenosis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079273

MicroRNA-1/133 targeted dysfunction of potassium channels KCNE1 and KCNQ1 in human cardiac progenitor cells with simulated hyperglycemia

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079273

MicroRNAs are essential for stretch-induced vascular smooth muscle contractile differentiation via microRNA (miR)-145-dependent expression of L-type calcium channels

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079273

KCNQ modulators reveal a key role for KCNQ potassium channels in regulating the tone of rat pulmonary artery smooth muscle

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079273

Bimodal effects of the Kv7 channel activator retigabine on vascular K+ currents

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079273

Molecular expression and pharmacological identification of a role for K(v)7 channels in murine vascular reactivity

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079273

Contribution of kv7.4/kv7.5 heteromers to intrinsic and calcitonin gene-related peptide-induced cerebral reactivity.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079273

Contribution of Kv7 channels to basal coronary flow and active response to ischemia.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079273

Reduced KCNQ4-encoded voltage-dependent potassium channel activity underlies impaired β-adrenoceptor-mediated relaxation of renal arteries in hypertension.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079273

Participation of KCNQ (Kv7) potassium channels in myogenic control of cerebral arterial diameter

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079273

Resistance artery mechanics, structure, and extracellular components in spontaneously hypertensive rats : effects of angiotensin receptor antagonism and converting enzyme inhibition.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079273

MicroRNA-190 regulates hypoxic pulmonary vasoconstriction by targeting a voltage-gated K⁺ channel in arterial smooth muscle cells

19 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27389411

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Contribution of Kv7 channels to natriuretic peptide mediated vasodilation in normal and hypertensive rats

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27389411

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Downregulation of Kv7.4 channel activity in primary and secondary hypertension

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27389411

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/CVR/CVW177

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27389411%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27389411%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

PubMed publication ID

27389411

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27389411%20AND%20SRC:MED&resulttype=core&format=json