The effect of antibody protein dose on the uniformity of tumor distribution of radioantibodies: an autoradiographic study (Q41130349)

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scientific article published on January 1991

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English	The effect of antibody protein dose on the uniformity of tumor distribution of radioantibodies: an autoradiographic study	scientific article published on January 1991

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scholarly article

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Europe PubMed Central

PubMed publication ID

1652355

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27 September 2017

title

The effect of antibody protein dose on the uniformity of tumor distribution of radioantibodies: an autoradiographic study (English)

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Europe PubMed Central

PubMed publication ID

1652355

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27 September 2017

author name string

R D Blumenthal

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1

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Europe PubMed Central

PubMed publication ID

1652355

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27 September 2017

I Fand

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2

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Europe PubMed Central

PubMed publication ID

1652355

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27 September 2017

R M Sharkey

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3

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Europe PubMed Central

PubMed publication ID

1652355

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27 September 2017

O C Boerman

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4

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Europe PubMed Central

PubMed publication ID

1652355

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27 September 2017

R Kashi

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5

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Europe PubMed Central

PubMed publication ID

1652355

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27 September 2017

D M Goldenberg

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6

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Europe PubMed Central

PubMed publication ID

1652355

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27 September 2017

publication date

1 January 1991

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Europe PubMed Central

PubMed publication ID

1652355

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27 September 2017

published in

Cancer Immunology, Immunotherapy

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Europe PubMed Central

PubMed publication ID

1652355

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27 September 2017

volume

33

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Europe PubMed Central

PubMed publication ID

1652355

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27 September 2017

issue

6

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Europe PubMed Central

PubMed publication ID

1652355

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27 September 2017

page(s)

351-358

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Europe PubMed Central

PubMed publication ID

1652355

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27 September 2017

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Intermittent blood flow in the KHT sarcoma--flow cytometry studies using Hoechst 33342.

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Use of a carbocyanine dye as a marker of functional vasculature in murine tumours

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Penetration of substances into tumour tissue. Model studies using saccharides, thymidine and thymidine-5'-triphosphate in cellular spheroids

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Diagnosis of and therapy for solid tumors with radiolabeled antibodies and immune fragments.

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https://pubmed.ncbi.nlm.nih.gov/1652355

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12 December 2020

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Determinants of tumor blood flow: a review

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12 December 2020

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Radioimmunotherapy of human colon carcinoma by 131I-labelled monoclonal anti-CEA antibodies in a nude mouse model

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12 December 2020

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Radioimmunotherapy of the GW-39 human colonic tumor xenograft with 131I-labeled murine monoclonal antibody to carcinoembryonic antigen

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Aspects of cytotoxic drug penetration, with particular reference to anthracyclines

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Mechanisms of heterogeneous distribution of monoclonal antibodies and other macromolecules in tumors: significance of elevated interstitial pressure

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12 December 2020

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Penetration and binding of antibodies in experimental human solid tumors grown in mice

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Comparison of tumor targeting of mouse monoclonal and goat polyclonal antibodies to carcinoembryonic antigen in the GW-39 human tumor-hamster host model

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Localization of monoclonal antibody AUA1 and its F(ab')2 fragments in human tumour xenografts: an autoradiographic and immunohistochemical study

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Radioimmunotherapy of cancer: clinical studies and limiting factors

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Quantitative whole-body autoradiography of radiolabeled antibody distribution in a xenografted human cancer model

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12 December 2020

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Penetration of substances into tumor tissue--a methodological study on cellular spheroids.

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GW-39: a new human tumor serially transplantable in the golden hamster

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12 December 2020

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The influence of monoclonal antibody dose on tumor uptake of radiolabeled antibody

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PubMed

reference URL

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12 December 2020

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A modeling analysis of monoclonal antibody percolation through tumors: a binding-site barrier.

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Murine monoclonal antibodies to colon-specific antigen p.

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Experimental radioimmunotherapy of a xenografted human colonic tumor (GW-39) producing carcinoembryonic antigen

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Percolation and binding of monoclonal antibody BW494 to pancreatic carcinoma tissues during high dose immunotherapy and consequences for future therapy modalities

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Relationship of radioantibody localization and cell viability in a xenografted human cancer model as measured by whole-body autoradiography

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Blood flow, oxygen consumption, and tissue oxygenation of human breast cancer xenografts in nude rats

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Cytotoxic drug penetration studies in multicellular tumour spheroids.

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Radioimmunotherapy of athymic mice bearing human colon carcinomas with monoclonal antibody B72.3: histological and autoradiographic study of effects on tumors and normal organs

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Influence of animal host and tumor implantation site on radio-antibody uptake in the GW-39 human colonic cancer xenograft

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Transport of molecules in the tumor interstitium: a review

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Effect of polarity and differentiation on antibody localization in multicellular tumour spheroid and xenograft models and its potential importance for in vivo immunotargeting

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Protein content and enzymatic assays of interstitial fluid from some normal tissues and transplanted mouse tumors

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Suppression of tumor vascular activity by radioantibody therapy: implications for multiple cycle treatments

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Dynamics of antibody transport and internalization

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Antibody protein dose and radioimmunodetection of GW-39 human colon tumor xenografts

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PubMed

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A human colon cancer metastasis model for radioimmunodetection

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Changes in antigen expression on human FME melanoma cells after exposure to hypoxia and acidic pH, alone or in combination

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Limited penetration of methotrexate into human osteosarcoma spheroids as a proposed model for solid tumor resistance to adjuvant chemotherapy

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Effect of dose, molecular size, affinity, and protein binding on tumor uptake of antibody or ligand: a biomathematical model

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Experimental radiotherapy of murine lymphoma with 131I-labeled anti-Thy 1.1 monoclonal antibody

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Comparison of therapeutic efficacy and host toxicity of two different 131I-labelled antibodies and their fragments in the GW-39 colonic cancer xenograft model

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A method of trace iodination of proteins for immunologic studies

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Transport of molecules across tumor vasculature

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The use of radionuclides for tumor therapy

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Use of radiolabelled monoclonal anti-CEA antibodies for the detection of human carcinomas by external photoscanning and tomoscintigraphy

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Phase I-II study of isotopic immunoglobulin therapy for primary liver cancer

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Radioimmunoscintigraphy and radioimmunotherapy of renal cell carcinoma xenografts

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Penetration and binding of radiolabeled anti-carcinoembryonic antigen monoclonal antibodies and their antigen binding fragments in human colon multicellular tumor spheroids

1 reference

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Interstitial fluid pressure in DMBA-induced rat mammary tumours

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Identifiers

DOI

10.1007/BF01741594

1 reference

stated in

Europe PubMed Central

PubMed publication ID

1652355

retrieved

27 September 2017

Dimensions Publication ID

1033085588

0 references

PubMed publication ID

1652355

1 reference

stated in

Europe PubMed Central

PubMed publication ID

1652355

retrieved

27 September 2017

 

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