Ranolazine selectively blocks persistent current evoked by epilepsy‐associated NaV1.1 mutations (Q41121995)

27 September 2017

Ranolazine selectively blocks persistent current evoked by epilepsy-associated Naν1.1 mutations (English)

1 reference

27 September 2017

Ranolazine selectively blocks persistent current evoked by epilepsy‐associated NaV1.1 mutations (English)

1 reference

Crossref

https://api.crossref.org/works/10.1111/J.1476-5381.2010.00976.X

22 June 2024

Irene Lepist

1 reference

27 September 2017

Kwan Leung

1 reference

27 September 2017

Sridharan Rajamani

1 reference

27 September 2017

Kristopher M. Kahlig

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20735403

22 June 2024

Alfred L. George

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20735403

22 June 2024

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English

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publication date

1 November 2010

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full work available at URL

27 September 2017

https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1476-5381.2010.00976.x

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20735403/?tool=EBI

22 June 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20735403

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20735403/pdf/?tool=EBI

22 June 2024

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https://europepmc.org/articles/PMC3000664

22 June 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20735403

https://europepmc.org/articles/PMC3000664?pdf=render

22 June 2024

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20735403

https://doi.org/10.1111/j.1476-5381.2010.00976.x

22 June 2024

online access status

open access

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20735403

https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1476-5381.2010.00976.x

22 June 2024

1 reference

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https://api.crossref.org/works/10.1111/J.1476-5381.2010.00976.X

https://bpspubs.onlinelibrary.wiley.com/doi/pdf/10.1111/j.1476-5381.2010.00976.x

22 June 2024

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British Journal of Pharmacology

22 June 2024

published in

1 reference

27 September 2017

161

1 reference

27 September 2017

1 reference

27 September 2017

1414-1426

1 reference

Use-dependent block of cardiac late Na(+) current by ranolazine

27 September 2017

1 reference

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Effects of ranolazine, a novel anti-anginal drug, on ion currents and membrane potential in pituitary tumor GH(3) cells and NG108-15 neuronal cells

27 September 2017

1 reference

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Block of tetrodotoxin-sensitive, Na(V)1.7 and tetrodotoxin-resistant, Na(V)1.8, Na+ channels by ranolazine

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000664

Ranolazine for chronic stable angina

27 September 2017

1 reference

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A catalog of SCN1A variants

27 September 2017

1 reference

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Divergent sodium channel defects in familial hemiplegic migraine

27 September 2017

1 reference

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Antiarrhythmic effects of ranolazine in canine pulmonary vein sleeve preparations.

27 September 2017

1 reference

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Rapid kinetic interactions of ranolazine with HERG K+ current

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000664

State- and use-dependent block of muscle Nav1.4 and neuronal Nav1.7 voltage-gated Na+ channel isoforms by ranolazine

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000664

Inhibition of late sodium current to reduce electrical and mechanical dysfunction of ischaemic myocardium

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000664

Severe myoclonic epilepsy in infancy: a systematic review and a meta-analysis of individual patient data

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000664

Persistent Sodium Current and Its Role in Epilepsy

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000664

Impaired inactivation gate stabilization predicts increased persistent current for an epilepsy-associated SCN1A mutation.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000664

Ranolazine for the treatment of chronic angina and potential use in other cardiovascular conditions

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000664

Molecular basis of ranolazine block of LQT-3 mutant sodium channels: evidence for site of action

27 September 2017

1 reference

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Sodium channel dysfunction in intractable childhood epilepsy with generalized tonic-clonic seizures

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000664

Sodium channel mutations in epilepsy and other neurological disorders

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000664

Inherited disorders of voltage-gated sodium channels

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000664

Mutation in the neuronal voltage-gated sodium channel SCN1A in familial hemiplegic migraine

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000664

SCN1A mutations and epilepsy

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000664

A novel epilepsy mutation in the sodium channel SCN1A identifies a cytoplasmic domain for beta subunit interaction

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000664

Noninactivating voltage-gated sodium channels in severe myoclonic epilepsy of infancy

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000664

Molecular basis of an inherited epilepsy

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000664

Pharmacological targeting of long QT mutant sodium channels

27 September 2017

1 reference

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Long QT syndrome patients with mutations of the SCN5A and HERG genes have differential responses to Na+ channel blockade and to increases in heart rate. Implications for gene-specific therapy.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000664

Analytical studies of rapidly inactivating and noninactivating sodium currents in differentiated NG108-15 neuronal cells

27 September 2017

1 reference

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The novel p.L1649Q mutation in the SCN1A epilepsy gene is associated with familial hemiplegic migraine: genetic and functional studies. Mutation in brief #957. Online

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000664

Antagonism by ranolazine of the pro-arrhythmic effects of increasing late INa in guinea pig ventricular myocytes

19 August 2018

1 reference

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Antiarrhythmic effects of ranolazine in a guinea pig in vitro model of long-QT syndrome

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000664

Evidence that ranolazine behaves as a weak beta1- and beta2-adrenoceptor antagonist in the rat [correction of cat] cardiovascular system

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000664

Guide to Receptors and Channels (GRAC), 4th Edition

19 August 2018

1 reference

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Modulation of alpha 1-adrenoceptors in rat left ventricle by ischaemia and acyl carnitines: protection by ranolazine

30 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000664

4 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/20735403

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

1 reference

27 September 2017

1 reference

27 September 2017

1 reference