Bystander Effects of Different Enzyme-Prodrug Systems for Cancer Gene Therapy Depend on Different Pathways for Intercellular Transfer of Toxic Metabolites, a Factor That Will Govern Clinical Choice of Appropriate Regimes (Q41081093)

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scientific article published on October 10, 1997

Language	Label	Description	Also known as
English	Bystander Effects of Different Enzyme-Prodrug Systems for Cancer Gene Therapy Depend on Different Pathways for Intercellular Transfer of Toxic Metabolites, a Factor That Will Govern Clinical Choice of Appropriate Regimes	scientific article published on October 10, 1997

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

26 September 2017

Bystander effects of different enzyme-prodrug systems for cancer gene therapy depend on different pathways for intercellular transfer of toxic metabolites, a factor that will govern clinical choice of appropriate regimes (English)

1 reference

Europe PubMed Central

PubMed publication ID

26 September 2017

Bystander Effects of Different Enzyme-Prodrug Systems for Cancer Gene Therapy Depend on Different Pathways for Intercellular Transfer of Toxic Metabolites, a Factor That Will Govern Clinical Choice of Appropriate Regimes (English)

1 reference

10.1089/HUM.1997.8.15-1825

https://api.crossref.org/works/10.1089/HUM.1997.8.15-1825

22 November 2024

0 references

cancer gene therapy

1 reference

based on heuristic

inferred from title

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9358032

22 November 2024

author name string

C. Denning

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9358032

22 November 2024

J. D. Pitts

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9358032

22 November 2024

language of work or name

1 reference

National Center for Biotechnology Information

PubMed publication ID

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=9358032

22 November 2024

publication date

1 October 1997

1 reference

Europe PubMed Central

PubMed publication ID

26 September 2017

10 October 1997

1 reference

National Center for Biotechnology Information

PubMed publication ID

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=9358032

22 November 2024

full work available at URL

http://www.liebertpub.com/doi/pdf/10.1089/hum.1997.8.15-1825

1 reference

10.1089/HUM.1997.8.15-1825

https://api.crossref.org/works/10.1089/HUM.1997.8.15-1825

22 November 2024

Human Gene Therapy

1 reference

Europe PubMed Central

PubMed publication ID

26 September 2017

8

1 reference

Europe PubMed Central

PubMed publication ID

26 September 2017

15

1 reference

Europe PubMed Central

PubMed publication ID

26 September 2017

1825-1835

1 reference

Europe PubMed Central

PubMed publication ID

26 September 2017

Lymphocytes transfer only the lysosomal form of alpha-D-mannosidase during cell-to-cell contact

1

1 reference

10.1089/HUM.1997.8.15-1825

https://api.crossref.org/works/10.1089/HUM.1997.8.15-1825

22 November 2024

Development of anti-tumor immunity following thymidine kinase-mediated killing of experimental brain tumors

2

1 reference

10.1089/HUM.1997.8.15-1825

https://api.crossref.org/works/10.1089/HUM.1997.8.15-1825

22 November 2024

In vitro evidence that metabolic cooperation is responsible for the bystander effect observed with HSV tk retroviral gene therapy

3

1 reference

10.1089/HUM.1997.8.15-1825

https://api.crossref.org/works/10.1089/HUM.1997.8.15-1825

22 November 2024

Expression of the bacterial nitroreductase enzyme in mammalian cells renders them selectively sensitive to killing by the prodrug CB1954.

4

1 reference

10.1089/HUM.1997.8.15-1825

https://api.crossref.org/works/10.1089/HUM.1997.8.15-1825

22 November 2024

The bystander effect of the nitroreductase/CB1954 enzyme/prodrug system is due to a cell-permeable metabolite

5

1 reference

10.1089/HUM.1997.8.15-1825

https://api.crossref.org/works/10.1089/HUM.1997.8.15-1825

22 November 2024

Somatic expression of herpes thymidine kinase in mice following injection of a fusion gene into eggs

6

1 reference

10.1089/HUM.1997.8.15-1825

https://api.crossref.org/works/10.1089/HUM.1997.8.15-1825

22 November 2024

Effect of herpes simplex virus thymidine kinase expression levels on ganciclovir-mediated cytotoxicity and the "bystander effect".

8

1 reference

10.1089/HUM.1997.8.15-1825

https://api.crossref.org/works/10.1089/HUM.1997.8.15-1825

22 November 2024

Unique spectrum of activity of 9-[(1,3-dihydroxy-2-propoxy)methyl]-guanine against herpesviruses in vitro and its mode of action against herpes simplex virus type 1

9

1 reference

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22 November 2024

In Vivo Gene Transfer with Retroviral Vector-Producer Cells for Treatment of Experimental Brain Tumors

10

1 reference

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22 November 2024

9-([2-hydroxy-1-(hydroxymethyl)ethoxy]methyl)guanine: a selective inhibitor of herpes group virus replication

12

1 reference

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22 November 2024

Disposition and orientation of ductin (DCCD-reactive vacuolar H(+)-ATPase subunit) in mammalian membrane complexes

13

1 reference

10.1089/HUM.1997.8.15-1825

https://api.crossref.org/works/10.1089/HUM.1997.8.15-1825

22 November 2024

Cancer Research

14

53

5274

author name string

PACKM A N

publication date

1993

1 reference

10.1089/HUM.1997.8.15-1825

https://api.crossref.org/works/10.1089/HUM.1997.8.15-1825

22 November 2024

Hypoxanthine-guanine phosphoribosyltransferase deficiency: chemical agents selective for mutant or normal cultured fibroblasts in mixed and heterozygote cultures

15

1 reference

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22 November 2024

Morphology of ricin and abrin exposed endothelial cells is consistent with apoptotic cell death

17

1 reference

10.1089/HUM.1997.8.15-1825

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22 November 2024

Bystander killing of cancer cells by herpes simplex virus thymidine kinase gene is mediated by connexins

20

1 reference

10.1089/HUM.1997.8.15-1825

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Lymphoma regression induced by ganciclovir in mice bearing a herpes thymidine kinase transgene.

21

1 reference

10.1089/HUM.1997.8.15-1825

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Metabolic suicide genes in gene therapy

22

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22 November 2024

Gene therapy for the treatment of brain tumors using intra-tumoral transduction with the thymidine kinase gene and intravenous ganciclovir

23

1 reference

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22 November 2024

Increased sensitivity to the prodrug 5'-deoxy-5-fluorouridine and modulation of 5-fluoro-2'-deoxyuridine sensitivity in MCF-7 cells transfected with thymidine phosphorylase

24

1 reference

10.1089/HUM.1997.8.15-1825

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22 November 2024

Cancer gene therapy: a bystander effect using the gap junctional pathway

25

1 reference

10.1089/HUM.1997.8.15-1825

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Quantitative aspects of accelerated nuclear polyploidization and tumour formation in dieldrin treated CF-1 mouse liver

27

1 reference

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Programmed cell death during mammary tissue involution induced by weaning, litter removal, and milk stasis

28

1 reference

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22 November 2024

Gene therapy for the treatment of malignant brain tumors with in vivo tumor transduction with the herpes simplex thymidine kinase gene/ganciclovir system

29

1 reference

10.1089/HUM.1997.8.15-1825

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22 November 2024

Metabolic co-operation between biochemically marked mammalian cells in tissue culture

31

1 reference

10.1089/HUM.1997.8.15-1825

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Use of suicide genes in gene therapy

32

1 reference

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Gap junctional intercellular communication and carcinogenesis

33

1 reference

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22 November 2024

Identifiers

10.1089/HUM.1997.8.15-1825

1 reference

Europe PubMed Central

PubMed publication ID

26 September 2017

release_olqk6iytpfer7h4l7afcm2xw2u

1 reference

https://api.fatcat.wiki/v0/release/olqk6iytpfer7h4l7afcm2xw2u

24 November 2022

based on heuristic

mapped directly with Wikidata item

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

26 September 2017

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