Mechanisms of chronic pain (Q41078770)

26 September 2017

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title

Mechanisms of chronic pain (English)

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26 September 2017

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J A Markenson

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26 September 2017

language of work or name

English

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publication date

1 July 1996

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American Journal of Medicine

26 September 2017

published in

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26 September 2017

volume

101

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26 September 2017

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26 September 2017

page(s)

6S-18S

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The sensitization of high threshold mechanoreceptors with myelinated axons by repeated heating

26 September 2017

cites work

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https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Response of cutaneous sensory units with unmyelinated fibers to noxious stimuli

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Nervous outflow from the cat's foot during noxious radiant heat stimulation

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Activity-dependent neuronal plasticity following tissue injury and inflammation

7 January 2021

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Peptides and the primary afferent nociceptor

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Peripheral and spinal neural mechanisms in arthritis, with particular reference to treatment of inflammation and pain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Antagonism of the algesic action of bradykinin on the human blister base

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Characterization of distinct phospholipases mediating bradykinin and noradrenaline hyperalgesia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Biochemical and Molecular Pharmacology of Kinin Receptors

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Protons selectively induce lasting excitation and sensitization to mechanical stimulation of nociceptors in rat skin, in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Identification of serotonin M-receptor subtypes and their specific blockade by a new class of drugs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

5-HT2 and 5-HT3 receptors mediate two distinct depolarizing responses in rat dorsal root ganglion neurons

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Serotonin is a directly-acting hyperalgesic agent in the rat.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Psychophysical Studies of the Itch Sensation and Itchy Skin (“Alloknesis”) Produced by Intracutaneous Injection of Histamine

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Histamine: an early messenger in inflammatory and immune reactions

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

The effects of bradykinin and prostaglandin E1 on rat cutaneous afferent nerve activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

PGI2-induced activation and sensitization of articular mechanonociceptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Further confirmation of the role of adenyl cyclase and of cAMP-dependent protein kinase in primary afferent hyperalgesia

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Human recombinant interleukin 1 stimulates collagenase and prostaglandin E2 production by human synovial cells

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Interleukin-8 as a mediator of sympathetic pain

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

The pivotal role of tumour necrosis factor alpha in the development of inflammatory hyperalgesia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Nerve growth factor regulates expression of neuropeptide genes in adult sensory neurons

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Nerve growth factor-induced hyperalgesia in the neonatal and adult rat

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Nerve growth factor in the synovial fluid of patients with chronic arthritis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Observations on the algogenic actions of adenosine compounds on the human blister base preparation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Direct cutaneous hyperalgesia induced by adenosine

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Synthesis, and central and peripheral axonal transport of substance P in a dorsal root ganglion-nerve preparation in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Release of substance P from peripheral nerve terminals following electrical stimulation of the sciatic nerve

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Substance P activation of rheumatoid synoviocytes: neural pathway in pathogenesis of arthritis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Electrophysiological evidence for a role of nitric oxide in prolonged chemical nociception in the rat

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Leukotriene B4Produces Hyperalgesia That Is Dependent on Polymorphonuclear Leukocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

The role of the polymorphonuclear leukocyte in hyperalgesia

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Morphine-like drugs inhibit the stimulation of E prostaglandins of cyclic AMP formation by rat brain homogenate

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Prostaglandin effects after elimination of indirect hyperalgesic mechanisms in the skin of the rat.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Kappa- and delta-opioids block sympathetically dependent hyperalgesia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Mechanisms of first and second pain in the peripheral and central nervous systems

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Peripheral, autonomic regulation of locus coeruleus noradrenergic neurons in brain: putative implications for psychiatry and psychopharmacology

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Corticotropin-releasing factor produces fear-enhancing and behavioral activating effects following infusion into the locus coeruleus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Acute pain in an emergency clinic: latency of onset and descriptor patterns related to different injuries

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Pain mechanisms: a new theory

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

The laminar organization of dorsal horn and effects of descending impulses

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Surgery in the Rat during Electrical Analgesia Induced by Focal Brain Stimulation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Analgesia from Electrical Stimulation in the Brainstem of the Rat

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Central nervous system mechanisms of analgesia

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Release of endogenous monoamines into spinal cord superfusates following the microinjection of phentolamine into the nucleus raphe magnus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Endogenous Pain Control Systems: Brainstem Spinal Pathways and Endorphin Circuitry

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Neurotransmitters in Nociceptive Modulatory Circuits

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Identification of two related pentapeptides from the brain with potent opiate agonist activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Peptides as neurotransmitters: focus on the enkephalins and endorphins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Organization of Endogenous Opiate and Nonopiate Pain Control Systems

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Sources of variability in the sensation of pain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Mu opiate isoreceptors: Differentiation with kappa agonists

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

The direct and specific opiate-like effect of met5-enkephalin and analogues on the spinal cord

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Hyperalgesia during naloxone-precipitated withdrawal from morphine is associated with increased on-cell activity in the rostral ventromedial medulla

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Gastrointestinal pharmacology

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Vagal bradycardia produced by microinjections of morphine-like drugs into the nucleus ambiguus in anaesthetized dogs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Central influences on spinal afferent conduction

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

DIFFERENTIAL SUPRASPINAL CONTROL OF INHIBITORY AND EXCITATORY ACTIONS FROM THE FRA TO ASCENDING SPINAL PATHWAYS.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Pain reduction by focal electrical stimulation of the brain: An anatomical and behavioral analysis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

A correlative anatomical and clinical study of pain suppression by deep brain stimulation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Autopsy analysis of the safety, efficacy and cartography of electrical stimulation of the central gray in humans

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Suppression by LSD of the inhibitory effect exerted by dorsal raphe stimulation on certain spinal cord interneurons in the cat

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Endogenous pain control mechanisms: Review and hypothesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Cortical projections to the periaqueductal gray in the monkey: A retrograde and orthograde horseradish peroxidase study

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Peptide immunoreactive neurons in the amygdala and the bed nucleus of the stria terminalis project to the midbrain central gray in the rat

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Contribution of brainstem GABAergic circuitry to descending antinociceptive controls: I. GABA-immunoreactive projection neurons in the periaqueductal gray and nucleus raphe magnus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Retrograde tracing of projections between the nucleus submedius, the ventrolateral orbital cortex, and the midbrain in the rat

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Organization of medullary adrenergic and noradrenergic projections to the periaqueductal gray matter in the rat

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Direct evidence that spinal serotonin and noradrenaline terminals mediate the spinal antinociceptive effects of morphine in the periaqueductal gray

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Antinociception induced by electrical stimulation of spinally projecting noradrenergic neurons in the A7 catecholamine cell group of the rat

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Analgesic effects of serotonin and receptor-selective serotonin agonists in the rat spinal cord

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

The noradrenergic innervation of the spinal cord: differences between two substrains of Sprague-Dawley rats determined using retrograde tracers combined with immunocytochemistry

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Morphine microinjected into the periaqueductal gray has differential effects on 3 classes of medullary neurons

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Projections of neurons in the ventromedial medulla to pontine catecholamine cell groups involved in the modulation of nociception

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

The projection of noradrenergic neurons in the A7 catecholamine cell group to the spinal cord in the rat demonstrated by anterograde tracing combined with immunocytochemistry

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Differential inhibitory effects of medial and lateral midbrain stimulation on spinal neuronal discharges to noxious skin heating in the cat.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Chronic stimulation of the Kölliker-Fuse nucleus region for relief of intractable pain in humans

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Excitatory amino acid-mediated components of synaptically evoked input from dorsal roots to deep dorsal horn neurons in the rat spinal cord slice.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Participation of excitatory amino acid receptors in the slow excitatory synaptic transmission in the rat spinal dorsal horn in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Activity-Dependent Changes in Rat Ventral Horn Neurons in vitro; Summation of Prolonged Afferent Evoked Postsynaptic Depolarizations Produce a d-2-Amino-5-Phosphonovaleric Acid Sensitive Windup.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Stimulus-transcription coupling in neurons: role of cellular immediate-early genes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

The antinociceptive action of supraspinal opioids results from an increase in descending inhibitory control: Correlation of nociceptive behavior and c-fos expression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Electrical stimulation in the medullary nucleus raphe magnus inhibits noxious heat-evoked fos protein-like immunoreactivity in the rat lumbar spinal cord

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

The induction and maintenance of central sensitization is dependent on N -methyl-d-aspartic acid receptor activation; implications for the treatment of post-injury pain hypersensitivity states

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

The combination of NMDA antagonism and morphine produces profound antinociception in the rat dorsal horn

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Studies on the spinal interaction of morphine and the NMDA antagonist MK-801 on the hyperesthesia observed in a rat model of sciatic mononeuropathy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Hyperalgesia mediated by spinal glutamate or substance P receptor blocked by spinal cyclooxygenase inhibition

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Relative effectiveness of C primary afferent fibers of different origins in evoking a prolonged facilitation of the flexor reflex in the rat.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Ectopic sensory discharges and paresthesiae in patients with disorders of peripheral nerves, dorsal roots and dorsal columns

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Phantom body pain in paraplegics: Evidence for a central “pattern generating mechanism” for pain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

The Relation of Pain to the Eysenck Personality Inventory, Cornell Medical Index and Whiteley Index of Hypochondriasis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Personality changes associated with reduction of pain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

A hypothesis on the physiological basis for causalgia and related pains

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Adrenergic excitation of cutaneous pain receptors induced by peripheral nerve injury

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Peripheral nerve injury triggers noradrenergic sprouting within dorsal root ganglia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

Phenoxybenzamine in the treatment of causalgia. Report of 40 cases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

The enigmatic role of the sympathetic nervous system in chronic pain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900133-7

10.1016/S0002-9343(96)00133-7

7 January 2021

Identifiers

DOI

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26 September 2017

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