An ancestral host defence peptide within human β-defensin 3 recapitulates the antibacterial and antiviral activity of the full-length molecule (Q41033958)

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scientific article published on 21 December 2015

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English	An ancestral host defence peptide within human β-defensin 3 recapitulates the antibacterial and antiviral activity of the full-length molecule	scientific article published on 21 December 2015

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scholarly article

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Europe PubMed Central

PMC publication ID

25 September 2017

An ancestral host defence peptide within human β-defensin 3 recapitulates the antibacterial and antiviral activity of the full-length molecule (English)

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Europe PubMed Central

PMC publication ID

25 September 2017

Daniela Sarnataro

3

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25 September 2017

Alfonso Carotenuto

8

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25 September 2017

Richard A. Urbanowicz

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25 September 2017

Francesco Salvatore

14

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25 September 2017

Veronica Folliero

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Veronica Folliero

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Gerardo Zambrano

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Gerardo Zambrano

5

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object named as

Jonathan K Ball

13

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Stefania Galdiero

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Stefania Galdiero

9

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1

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Ersilia Nigro

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25 September 2017

4

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Olga Scudiero

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Aurora Daniele

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2

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Irene Colavita

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25 September 2017

Massimiliano Galdiero

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Massimiliano Galdiero

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25 September 2017

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Vincenzo Granata

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25 September 2017

Antonello Pessi

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25 September 2017

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publication date

21 December 2015

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Scientific Reports

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5

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25 September 2017

18450

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Europe PubMed Central

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25 September 2017

copyright license

Creative Commons Attribution 4.0 International

21 December 2015

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April 2022 Public Data File from Crossref

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Design and activity of a cyclic mini-β-defensin analog: a novel antimicrobial tool.

1 reference

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Herpes Simplex Virus 1 Recruits CD98 Heavy Chain and β1 Integrin to the Nuclear Membrane for Viral De-Envelopment

1 reference

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Membrane protein 4F2/CD98 is a cell surface receptor involved in the internalization and trafficking of human β-Defensin 3 in epithelial cells

1 reference

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Dramatic potentiation of the antiviral activity of HIV antibodies by cholesterol conjugation

1 reference

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Membrane disruptive antimicrobial activities of human β-defensin-3 analogs

1 reference

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Defensins and viral infection: dispelling common misconceptions.

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Molecular and functional analysis of human β-defensin 3 action at melanocortin receptors

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Defensins: natural component of human innate immunity

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Novel α-MSH peptide analogues with broad spectrum antimicrobial activity

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Chimeric beta-defensin analogs, including the novel 3NI analog, display salt-resistant antimicrobial activity and lack toxicity in human epithelial cell lines

1 reference

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Intestinal epithelial CD98 directly modulates the innate host response to enteric bacterial pathogens.

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Does cholesterol suppress the antimicrobial peptide induced disruption of lipid raft containing membranes?

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β-Defensins: multifunctional modulators of infection, inflammation and more?

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The lipid raft-associated protein CD98 is required for vaccinia virus endocytosis

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Emerging themes and therapeutic prospects for anti-infective peptides.

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Biosynthesis and antimicrobial evaluation of backbone-cyclized α-defensins

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The pathogenic E. coli type III effector EspZ interacts with host CD98 and facilitates host cell prosurvival signalling

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26 September 2017

Novel synthetic, salt-resistant analogs of human beta-defensins 1 and 3 endowed with enhanced antimicrobial activity

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Sampling the N-terminal proteome of human blood

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Host defense peptides as effector molecules of the innate immune response: a sledgehammer for drug resistance?

1 reference

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Beyond NMR spectra of antimicrobial peptides: dynamical images at atomic resolution and functional insights

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Structure, membrane orientation, mechanism, and function of pexiganan--a highly potent antimicrobial peptide designed from magainin.

1 reference

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Antifungal activities of human beta-defensins HBD-1 to HBD-3 and their C-terminal analogs Phd1 to Phd3.

1 reference

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Studies on anticancer activities of antimicrobial peptides

1 reference

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A -defensin mutation causes black coat color in domestic dogs

1 reference

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Unifying themes in host defence effector polypeptides

1 reference

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Antiviral activity of human beta-defensin 3 against vaccinia virus

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Antimicrobial and host-defense peptides as new anti-infective therapeutic strategies

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26 September 2017

The human beta-defensin-3, an antibacterial peptide with multiple biological functions

1 reference

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26 September 2017

Human beta-defensins

1 reference

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Role of human beta-defensins in HIV infection

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Solid-state NMR investigation of the membrane-disrupting mechanism of antimicrobial peptides MSI-78 and MSI-594 derived from magainin 2 and melittin

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Carbohydrate-binding molecules inhibit viral fusion and entry by crosslinking membrane glycoproteins

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Reconstruction of the conserved beta-bulge in mammalian defensins using D-amino acids.

1 reference

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Multidimensional signatures in antimicrobial peptides

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Human epithelial beta-defensins 2 and 3 inhibit HIV-1 replication

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Defensins: antimicrobial peptides of innate immunity

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Antimicrobial characterization of human beta-defensin 3 derivatives

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Inactivation of human beta-defensins 2 and 3 by elastolytic cathepsins

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Mechanism of lipid bilayer disruption by the human antimicrobial peptide, LL-37.

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MSI-78, an Analogue of the Magainin Antimicrobial Peptides, Disrupts Lipid Bilayer Structure via Positive Curvature Strain

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The novel human beta-defensin-3 is widely expressed in oral tissues

1 reference

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[beta]-defensins in lung host defense

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The solution structures of the human beta-defensins lead to a better understanding of the potent bactericidal activity of HBD3 against Staphylococcus aureus

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Isolation and characterization of human beta -defensin-3, a novel human inducible peptide antibiotic

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'Random coil' 1H chemical shifts obtained as a function of temperature and trifluoroethanol concentration for the peptide series GGXGG.

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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Antibacterial activities of synthetic peptides corresponding to the carboxy-terminal region of human beta-defensins 1-3.

1 reference

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Structural congruence among membrane-active host defense polypeptides of diverse phylogeny.

1 reference

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Detergent-Type Membrane Fragmentation by MSI-78, MSI-367, MSI-594, and MSI-843 Antimicrobial Peptides and Inhibition by Cholesterol: A Solid-State Nuclear Magnetic Resonance Study

1 reference

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PISEMA Solid-State NMR Spectroscopy

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21 January 2018

Identifiers

10.1038/SREP18450

1 reference

Europe PubMed Central

PMC publication ID

25 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

25 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

25 September 2017

ResearchGate publication ID

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