PC5-A-mediated processing of pro-neurotensin in early compartments of the regulated secretory pathway of PC5-transfected PC12 cells (Q41008817)

25 September 2017

title

PC5-A-mediated processing of pro-neurotensin in early compartments of the regulated secretory pathway of PC5-transfected PC12 cells (English)

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25 September 2017

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25 September 2017

Barbero P

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25 September 2017

Rovère C

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25 September 2017

De Bie I

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25 September 2017

Beaudet A

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25 September 2017

Kitabgi P

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25 September 2017

language of work or name

English

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publication date

1 September 1998

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Journal of Biological Chemistry

25 September 2017

published in

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25 September 2017

volume

273

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25 September 2017

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25 September 2017

page(s)

25339-25346

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Sorting and processing of secretory proteins

25 September 2017

cites work

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The family of subtilisin/kexin like pro-protein and pro-hormone convertases: divergent or shared functions

21 January 2018

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cDNA sequence of two distinct pituitary proteins homologous to Kex2 and furin gene products: tissue-specific mRNAs encoding candidates for pro-hormone processing proteinases

21 January 2018

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Cloning and primary sequence of a mouse candidate prohormone convertase PC1 homologous to PC2, Furin, and Kex2: distinct chromosomal localization and messenger RNA distribution in brain and pituitary compared to PC2.

21 January 2018

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Identification of a cDNA encoding a second putative prohormone convertase related to PC2 in AtT20 cells and islets of Langerhans

21 January 2018

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A member of the eukaryotic subtilisin family (PC3) has the enzymic properties of the type 1 proinsulin-converting endopeptidase

21 January 2018

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Proinsulin processing by the subtilisin-related proprotein convertases furin, PC2, and PC3

21 January 2018

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Proglucagon is processed to glucagon by prohormone convertase PC2 in alpha TC1-6 cells

21 January 2018

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Processing of mouse proglucagon by recombinant prohormone convertase 1 and immunopurified prohormone convertase 2 in vitro

21 January 2018

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Differential Processing of Proglucagon by the Subtilisin-like Prohormone Convertases PC2 and PC3 to Generate either Glucagon or Glucagon-like Peptide

21 January 2018

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PC1 and PC2 are proprotein convertases capable of cleaving proopiomelanocortin at distinct pairs of basic residues

21 January 2018

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21 January 2018

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21 January 2018

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Identification and functional expression of a new member of the mammalian Kex2-like processing endoprotease family: its striking structural similarity to PACE4

21 January 2018

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Identification of an isoform with an extremely large Cys-rich region of PC6, a Kex2-like processing endoprotease

21 January 2018

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The isoforms of proprotein convertase PC5 are sorted to different subcellular compartments

21 January 2018

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Bioactivation of Müllerian inhibiting substance during gonadal development by a kex2/subtilisin-like endoprotease

21 January 2018

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Increased proteolytic processing of protein tyrosine phosphatase mu in confluent vascular endothelial cells: the role of PC5, a member of the subtilisin family

21 January 2018

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Induction of the neurotensin (NT) gene in PC12 cells gives rise to NT precursor (approximately 88%), NT(3-13)-like peptide (approximately 10%), and NT (approximately 2%).

21 January 2018

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PC12 cells can be induced to produce, but do not process, the neurotensin/neuromedin N precursor.

21 January 2018

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Cellular distributions of the prohormone processing enzymes PC1 and PC2.

21 January 2018

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Posttranslational processing of the neurotensin/neuromedin-N precursor

21 January 2018

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Post-translational processing of the neurotensin/neuromedin N precursor in the central nervous system of the rat--I. Biochemical characterization of maturation products

21 January 2018

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Purification of large neuromedin N (NMN) from canine intestine and its identification as NMN-125.

21 January 2018

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Differential processing of the neurotensin/neuromedin N precursor in the mouse

21 January 2018

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Neurotensin in the adrenal medulla

21 January 2018

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Tissue-specific processing of neurotensin/neuromedin-N precursor in cat.

21 January 2018

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Cloning and sequence analysis of cDNA for the canine neurotensin/neuromedin N precursor

21 January 2018

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Evidence that PC2 is the endogenous pro-neurotensin convertase in rMTC 6-23 cells and that PC1- and PC2-transfected PC12 cells differentially process pro-neurotensin

21 January 2018

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21 January 2018

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Syntaxin 6 functions in trans-Golgi network vesicle trafficking

21 January 2018

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Immunological and biochemical characterization of processing products from the neurotensin/neuromedin N precursor in the rat medullary thyroid carcinoma 6-23 cell line

21 January 2018

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Biogenesis of secretory granules. Implications arising from the immature secretory granule in the regulated pathway of secretion

21 January 2018

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Characterization of the endopeptidase PC2 activity towards secretogranin II in stably transfected PC12 cells

21 January 2018

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Two activation states of the prohormone convertase PC1 in the secretory pathway

21 January 2018

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Simultaneous release of neurotensin, somatostatin, enkephalins and catecholamines from perfused cat adrenal glands

21 January 2018

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Transsynaptic regulation of galanin, neurotensin, and substance P in the adrenal medulla: combinatorial control by second-messenger signaling pathways

21 January 2018

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Neurotensin-like immunoreactivity in a subpopulation of noradrenaline-containing cells of the cat adrenal gland

21 January 2018

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Mutational analysis of PC1 (SPC3) in PC12 cells. 66-kDa PC1 is fully functional.

21 January 2018

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Pro-neurotensin/neuromedin N expression and processing in human colon cancer cell lines

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.273.39.25339

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25 September 2017

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