A proportion of proteinase 3 (PR3)-specific anti-neutrophil cytoplasmic antibodies (ANCA) only react with PR3 after cleavage of its N-terminal activation dipeptide (Q40993947)

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scientific article published on November 1998

Language	Label	Description	Also known as
English	A proportion of proteinase 3 (PR3)-specific anti-neutrophil cytoplasmic antibodies (ANCA) only react with PR3 after cleavage of its N-terminal activation dipeptide	scientific article published on November 1998

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

25 September 2017

A proportion of proteinase 3 (PR3)-specific anti-neutrophil cytoplasmic antibodies (ANCA) only react with PR3 after cleavage of its N-terminal activation dipeptide (English)

1 reference

Europe PubMed Central

PubMed publication ID

25 September 2017

author name string

Sun J

1

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Europe PubMed Central

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25 September 2017

Fass DN

2

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Europe PubMed Central

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25 September 2017

Viss MA

3

1 reference

Europe PubMed Central

PubMed publication ID

25 September 2017

Hummel AM

4

1 reference

Europe PubMed Central

PubMed publication ID

25 September 2017

Tang H

5

1 reference

Europe PubMed Central

PubMed publication ID

25 September 2017

Homburger HA

6

1 reference

Europe PubMed Central

PubMed publication ID

25 September 2017

Specks U

7

1 reference

Europe PubMed Central

PubMed publication ID

25 September 2017

publication date

1 November 1998

1 reference

Europe PubMed Central

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25 September 2017

Clinical and Experimental Immunology

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Europe PubMed Central

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25 September 2017

114

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Europe PubMed Central

PubMed publication ID

25 September 2017

2

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25 September 2017

320-326

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Europe PubMed Central

PubMed publication ID

25 September 2017

Capture-ELISA based on recombinant PR3 is sensitive for PR3-ANCA testing and allows detection of PR3 and PR3-ANCA/PR3 immunecomplexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1905112

29 August 2018

Antineutrophil cytoplasmic antibodies induce monocyte IL-8 release. Role of surface proteinase-3, alpha1-antitrypsin, and Fcgamma receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1905112

29 August 2018

The crystal structure of PR3, a neutrophil serine proteinase antigen of Wegener's granulomatosis antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1905112

29 August 2018

Recombinant human proteinase 3, the Wegener's autoantigen, expressed in HMC-1 cells is enzymatically active and recognized by c-ANCA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1905112

29 August 2018

Characterization of a recombinant proteinase 3, the autoantigen in Wegener's granulomatosis and its reactivity with anti-neutrophil cytoplasmic autoantibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1905112

29 August 2018

Expression of the human autoantigen of Wegener's granulomatosis (PR3) in a baculovirus expression system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1905112

29 August 2018

Anti-neutrophil cytoplasmic antibodies: current diagnostic and pathophysiological potential

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1905112

29 August 2018

Immunodiagnostic and pathophysiologic aspects of antineutrophil cytoplasmic antibodies in vasculitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1905112

29 August 2018

In vitro processing of human tumor necrosis factor-alpha.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1905112

29 August 2018

Epitope mapping of anti-proteinase 3 and anti-myeloperoxidase antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1905112

29 August 2018

Engineering hybrid genes without the use of restriction enzymes: gene splicing by overlap extension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1905112

29 August 2018

Wegener's autoantigen decoded

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1905112

29 August 2018

Cloning of cDNA for proteinase 3: a serine protease, antibiotic, and autoantigen from human neutrophils

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1905112

29 August 2018

Identity of Wegener's autoantigen (p29) with proteinase 3 and myeloblastin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1905112

29 August 2018

Anti-neutrophil cytoplasmic autoantibodies induce neutrophils to degranulate and produce oxygen radicals in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1905112

29 August 2018

Structure of recombinant N-terminal globule of type VI collagen alpha 3 chain and its binding to heparin and hyaluronan

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1905112

29 August 2018

Antineutrophil cytoplasmic autoantibodies in Wegener's granulomatosis recognize conformational epitope(s) on proteinase 3

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1905112

29 August 2018

Anticytoplasmic autoantibodies: their immunodiagnostic value in Wegener granulomatosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/9822293

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-neutrophil cytoplasm antibodies in Wegener's granulomatosis: immunodiagnostic value, monoclonal antibodies and characterization of the target antigen

1 reference

https://pubmed.ncbi.nlm.nih.gov/9822293

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Limited prognostic value of changes in antineutrophil cytoplasmic antibody titer in patients with Wegener's granulomatosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/9822293

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cleavage and inactivation of human C1 inhibitor by the human leukocyte proteinase, proteinase 3

1 reference

https://pubmed.ncbi.nlm.nih.gov/9822293

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epitopes on proteinase-3 recognized by antibodies from patients with Wegener's granulomatosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/9822293

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neutrophil activation in vitro and in vivo in Wegener's granulomatosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/9822293

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-neutrophil cytoplasmic antibodies engage and activate human neutrophils via Fc gamma RIIa

1 reference

https://pubmed.ncbi.nlm.nih.gov/9822293

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Screening for anti-neutrophil cytoplasmic antibodies (ANCA): is indirect immunofluorescence the method of choice?

1 reference

https://pubmed.ncbi.nlm.nih.gov/9822293

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of tumor necrosis factor-induced integrin activation on Fc gamma receptor II-mediated signal transduction: relevance for activation of neutrophils by anti-proteinase 3 or anti-myeloperoxidase antibodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/9822293

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antibodies to neutrophil cytoplasmic antigens induce monocyte chemoattractant protein-1 secretion from human monocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/9822293

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of monoclonal antibodies to proteinase-3 and application in the study of epitopes for classical anti-neutrophil cytoplasm antibodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/9822293

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-1 beta production by human polymorphonuclear leucocytes stimulated by anti-neutrophil cytoplasmic autoantibodies: relevance to systemic vasculitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/9822293

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human mast cells expressing recombinant proteinase 3 (PR3) as substrate for clinical testing for anti-neutrophil cytoplasmic antibodies (ANCA)

1 reference

https://pubmed.ncbi.nlm.nih.gov/9822293

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recombinant proteinase 3 (Wegener's antigen) expressed inPichia pastorisis functionally active and is recognized by patient sera

1 reference

https://pubmed.ncbi.nlm.nih.gov/9822293

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1046/J.1365-2249.1998.00730.X

1 reference

Europe PubMed Central

PubMed publication ID

25 September 2017

PMC publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

25 September 2017

ResearchGate publication ID

0 references

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