Mutation and cancer: a personal odyssey (Q40951665)

25 September 2017

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title

Mutation and cancer: a personal odyssey (English)

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25 September 2017

Knudson AG Jr

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25 September 2017

publication date

1 January 1995

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Advances in Cancer Research

25 September 2017

published in

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25 September 2017

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25 September 2017

page(s)

1-23

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Carcinogens are mutagens: a simple test system combining liver homogenates for activation and bacteria for detection

25 September 2017

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7 January 2021

THE ROLE OF DEOXYRIBONUCLEIC ACID IN THE SYNTHESIS OF ROUS SARCOMA VIRUS.

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7 January 2021

Chromosome 17 deletions and p53 gene mutations in colorectal carcinomas

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7 January 2021

RNA-dependent DNA polymerase in virions of RNA tumour viruses

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7 January 2021

Morphological conversion of cell cultures by avian myeloblastosis virus

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7 January 2021

In vivo infectivity studies with avian mveloblastosis virus

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7 January 2021

DNA complementary to viral RNA in leukemic cells induced by avian myeloblastosis virus

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7 January 2021

Patient with 13 Chromosome Deletion: Evidence That the Retinoblastoma Gene Is a Recessive Cancer Gene

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7 January 2021

A new, quantitative, approach to the study of the stages of chemical cartinogenesis in the mouse's skin

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7 January 2021

A specific complement-fixing antigen present in SV 40 tumor and transformed cells.

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7 January 2021

EVIDENCE FOR THE BINDING OF POLYNUCLEAR AROMATIC HYDROCARBONS TO THE NUCLEIC ACIDS OF MOUSE SKIN: RELATION BETWEEN CARCINOGENIC POWER OF HYDROCARBONS AND THEIR BINDING TO DEOXYRIBONUCLEIC ACID.

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7 January 2021

Intracellular Forms of Adenovirus DNA III. Integration of the DNA of Adenovirus Type 2 into Host DNA in Productively Infected Cells

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7 January 2021

The retinoblastoma protein is phosphorylated during specific phases of the cell cycle

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7 January 2021

Expression of recessive alleles by chromosomal mechanisms in retinoblastoma

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7 January 2021

Genetic origin of mutations predisposing to retinoblastoma

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7 January 2021

Phosphorylation of the retinoblastoma gene product is modulated during the cell cycle and cellular differentiation

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7 January 2021

Thymocyte apoptosis induced by p53-dependent and independent pathways.

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7 January 2021

Defective Repair Replication of DNA in Xeroderma Pigmentosum

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7 January 2021

Amplification of endogenous myc-related DNA sequences in a human myeloid leukaemia cell line

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7 January 2021

A general theory of carcinogenesis

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7 January 2021

Human c-myc onc gene is located on the region of chromosome 8 that is translocated in Burkitt lymphoma cells

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7 January 2021

Onc gene amplification in promyelocytic leukaemia cell line HL-60 and primary leukaemic cells of the same patient

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https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene

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https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

The product of the retinoblastoma susceptibility gene has properties of a cell cycle regulatory element

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https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

A cellular oncogene is translocated to the Philadelphia chromosome in chronic myelocytic leukaemia

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

Detection of a transformation-related antigen in chemically induced sarcomas and other transformed cells of the mouse

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https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

Transforming genes of human bladder and lung carcinoma cell lines are homologous to the ras genes of Harvey and Kirsten sarcoma viruses

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https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

p53 functions as a cell cycle control protein in osteosarcomas

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https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

Differences between the ribonucleic acids of transforming and nontransforming avian tumor viruses

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https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product

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https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

FAMILIAL RENAL ADENOMAS IN WISTAR RATS

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https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

Transcriptional activation of the translocated c-myc oncogene in burkitt lymphoma

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

Genetics of retinoblastoma.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

A genetic model for colorectal tumorigenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

Clonal origin of chronic myelocytic leukemia in man

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

Sporadic bilateral retinoblastoma and 13q- chromosomal deletion

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

CELL-TRANSFORMING ABILITY OF A TEMPERATURE-SENSITIVE MUTANT OF POLYOMA VIRUS

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

THE INITIATING AND PROMOTING ELEMENTS IN TUMOR PRODUCTION : AN ANALYSIS OF THE EFFECTS OF TAR, BENZPYRENE, AND METHYLCHOLANTHRENE ON RABBIT SKIN.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma

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https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

Structural evidence for the authenticity of the human retinoblastoma gene

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

Somatic inactivation of genes on chromosome 13 is a common event in retinoblastoma

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https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

Antigenic properties of cells transformed by polyoma virus

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https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

Translocation joins c-myc and immunoglobulin gamma 1 genes in a Burkitt lymphoma revealing a third exon in the c-myc oncogene.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

Suppression of Malignancy by Cell Fusion

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https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

Activation of a cellular onc gene by promoter insertion in ALV-induced lymphoid leukosis

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7 January 2021

Model for the incidence of embryonal cancers: application to retinoblastoma

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7 January 2021

Spontaneous and radiation-induced renal tumors in the Eker rat model of dominantly inherited cancer

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https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

Integration of simian virus 40 deoxyribonucleic acid into the deoxyribonucleic acid of permissive monkey kidney cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

Suppression of the neoplastic phenotype by replacement of the RB gene in human cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

Oncogenes of RNA tumor viruses as determinants of cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

SPECIFIC ADENOVIRUS COMPLEMENT-FIXING ANTIGENS IN VIRUS-FREE HAMSTER AND RAT TUMORS

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

The role of gene dosage and genetic transpositions in carcinogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

The approaching era of the tumor suppressor genes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

ETHNIC DIFFERENCES IN CHILDHOOD LEUKEMIA AS REVEALED BY A STUDY OF ANTECEDENT VARIABLES.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

Mutation and cancer: statistical study of retinoblastoma

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

Model Hereditary Cancers of Man

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

Neuroblastoma and ganglioneuroma in a child with multiple neurofibromatosis. Implications for the mutational origin of neuroblastoma

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

Mutation and childhood cancer: a probabilistic model for the incidence of retinoblastoma

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

Chromosomal deletion and retinoblastoma

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

A germline insertion in the tuberous sclerosis (Tsc2) gene gives rise to the Eker rat model of dominantly inherited cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

Computer-assisted analysis of chromosomal abnormalities: detection of a deletion in aniridia-Wilms' tumor syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes

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7 January 2021

T antigen is bound to a host protein in SY40-transformed cells

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7 January 2021

Human retinoblastoma susceptibility gene: cloning, identification, and sequence

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7 January 2021

The retinoblastoma susceptibility gene encodes a nuclear phosphoprotein associated with DNA binding activity

1 reference

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7 January 2021

CHROMOSOME DELETION IN A CASE OF RETINOBLASTOMA.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

Characterization of a 54K Dalton cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells

1 reference

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7 January 2021

Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53

1 reference

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7 January 2021

p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

1 reference

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7 January 2021

p53 is required for radiation-induced apoptosis in mouse thymocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms

1 reference

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7 January 2021

Marker band in one chromosome 14 from Burkitt lymphomas.

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7 January 2021

Genesis of the 14q+ marker in Burkitt's lymphoma

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7 January 2021

Rous sarcoma virus: a function required for the maintenance of the transformed state

1 reference

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7 January 2021

ASSOCIATION OF WILMS'S TUMOR WITH ANIRIDIA, HEMIHYPERTROPHY AND OTHER CONGENITAL MALFORMATIONS

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

Mutation and cancer: a model for human carcinogenesis

1 reference

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7 January 2021

ARTIFICIAL TRANSMUTATION OF THE GENE

1 reference

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7 January 2021

A new theory on cancer-inducing mechanism

1 reference

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7 January 2021

Foundations in cancer research. Chromosomes and cancer: the evolution of an idea.

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7 January 2021

Human EJ bladder carcinoma oncogene is homologue of Harvey sarcoma virus ras gene

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

Chemical Effect of Ionizing Radiation on Cytosine

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

IMMUNOFLUORESCENT STUDIES OF ADENOVIRUS 12 TUMORS AND OF CELLS TRANSFORMED OR INFECTED BY ADENOVIRUSES

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

Chromosomal translocations in human cancer.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

DNA in uninfected and virus-infected cells complementary to avian tumor virus RNA

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

CONDITIONAL NEOPLASMS AND SUBTHRESHOLD NEOPLASTIC STATES : A STUDY OF THE TAR TUMORS OF RABBITS.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

Letter: A new consistent chromosomal abnormality in chronic myelogenous leukaemia identified by quinacrine fluorescence and Giemsa staining

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

Adenovirus early region 1A enables viral and cellular transforming genes to transform primary cells in culture

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

The integrated state of viral DNA in SV40-transformed cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

T24 human bladder carcinoma oncogene is an activated form of the normal human homologue of BALB- and Harvey-MSV transforming genes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

The heredity of retinoblastoma

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

A cellular oncogene (c-Ki-ras) is amplified, overexpressed and located within karyotypic abnormalities in mouse adrenocortical tumour cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

Induction of apoptosis by wild-type p53 in a human colon tumor-derived cell line.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

Transformation induced by simian virus 40 in human renal cell cultures. I. Morphology and growth characteristics

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

Expression of the wild-type p53 antioncogene induces guanine nucleotide-dependent stem cell division kinetics

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

Passage of phenotypes of chemically transformed cells via transfection of DNA and chromatin

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

Regional assignment of genes for human esterase D and retinoblastoma to chromosome band 13q14

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

Gene for hereditary retinoblastoma assigned to human chromosome 13 by linkage to esterase D

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

Suppression of malignancy in human cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

Replication of the genome of a hepatitis B-like virus by reverse transcription of an RNA intermediate

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

Translocation of the c-myc gene into the immunoglobulin heavy chain locus in human Burkitt lymphoma and murine plasmacytoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

THE EFFECTS OF ACTINOMYCIN D ON GROWTH OF ROUS SARCOMA VIRUS IN VITRO.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

THE PARTICIPATION OF DNA IN ROUS SARCOMA VIRUS PRODUCTION.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

HOMOLOGY BETWEEN RNA FROM ROUS SARCOMA VIROUS AND DNA FROM ROUS SARCOMA VIRUS-INFECTED CELLS

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

Viral RNA-dependent DNA Polymerase: RNA-dependent DNA Polymerase in Virions of Rous Sarcoma Virus

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

Temperature sensitive mutants of an avian sarcoma virus.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

VIRUS-CELL INTERACTION WITH A TUMOR-PRODUCING VIRUS

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

Steps in the neoplastic transformation of hamster embryo cells by polyoma virus

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

Association between an oncogene and an anti-oncogene: the adenovirus E1A proteins bind to the retinoblastoma gene product

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

Predisposition to renal carcinoma in the Eker rat is determined by germ-line mutation of the tuberous sclerosis 2 (TSC2) gene

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

Characteristic chromosomal abnormalities in biopsies and lymphoid-cell lines from patients with Burkitt and non-Burkitt lymphomas

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960708-3

7 January 2021

10.1016/S0065-230X(08)60708-3

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