Hybrid transgenic mice reveal in vivo specificity of G protein-coupled receptor kinases in the heart (Q40892894)

24 September 2017

title

Hybrid transgenic mice reveal in vivo specificity of G protein-coupled receptor kinases in the heart (English)

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G protein-coupled receptor

24 September 2017

main subject

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Lefkowitz RJ

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24 September 2017

Eckhart AD

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24 September 2017

Duncan SJ

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24 September 2017

Penn RB

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24 September 2017

Benovic JL

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24 September 2017

Koch WJ

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24 September 2017

publication date

1 January 2000

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24 September 2017

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24 September 2017

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24 September 2017

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24 September 2017

page(s)

43-50

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Phosphorylation of the type 1A angiotensin II receptor by G protein-coupled receptor kinases and protein kinase C

24 September 2017

cites work

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Adrenergic receptor stimulation of the mitogen-activated protein kinase cascade and cardiac hypertrophy

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Alpha1-adrenergic receptor subtype mRNAs are differentially regulated by alpha1-adrenergic and other hypertrophic stimuli in cardiac myocytes in culture and in vivo. Repression of alpha1B and alpha1D but induction of alpha1C.

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Role of beta gamma subunits of G proteins in targeting the beta-adrenergic receptor kinase to membrane-bound receptors

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11 October 2022

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Mechanisms of beta-adrenergic receptor desensitization: from molecular biology to heart failure

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Mutational analysis of the pleckstrin homology domain of the beta-adrenergic receptor kinase. Differential effects on G beta gamma and phosphatidylinositol 4,5-bisphosphate binding

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Targeting the receptor-Gq interface to inhibit in vivo pressure overload myocardial hypertrophy

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11 October 2022

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G protein-coupled receptors. III. New roles for receptor kinases and beta-arrestins in receptor signaling and desensitization

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Extracellular signal-regulated protein kinase activation is required for the anti-hypertrophic effect of atrial natriuretic factor in neonatal rat ventricular myocytes

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11 October 2022

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Receptor and G betagamma isoform-specific interactions with G protein-coupled receptor kinases

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Atrial natriuretic polypeptide inhibits hypertrophy of vascular smooth muscle cells

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Effect of different G protein-coupled receptor kinases on phosphorylation and desensitization of the alpha1B-adrenergic receptor

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Distribution of alpha1-adrenergic receptor mRNA species in rat heart

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Transgenic mice with cardiac overexpression of alpha1B-adrenergic receptors. In vivo alpha1-adrenergic receptor-mediated regulation of beta-adrenergic signaling

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11 October 2022

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Phosphorylation and desensitization of human endothelin A and B receptors. Evidence for G protein-coupled receptor kinase specificity

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11 October 2022

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Identification of a short sequence highly divergent between beta-adrenergic-receptor kinases 1 and 2 that determines the affinity of binding to betagamma subunits of heterotrimeric guanine-nucleotide-binding regulatory proteins

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Cardiac function in mice overexpressing the beta-adrenergic receptor kinase or a beta ARK inhibitor

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11 October 2022

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Receptor-specific in vivo desensitization by the G protein-coupled receptor kinase-5 in transgenic mice

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11 October 2022

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Nitric oxide, atrial natriuretic peptide, and cyclic GMP inhibit the growth-promoting effects of norepinephrine in cardiac myocytes and fibroblasts

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11 October 2022

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Mitogen-activated protein kinases mediate changes in gene expression, but not cytoskeletal organization associated with cardiac muscle cell hypertrophy

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11 October 2022

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Myocardial expression of a constitutively active alpha 1B-adrenergic receptor in transgenic mice induces cardiac hypertrophy

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11 October 2022

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Selective regulation of G protein-coupled receptor-mediated signaling by G protein-coupled receptor kinase 2 in FRTL-5 cells: analysis of thyrotropin, alpha(1B)-adrenergic, and A(1) adenosine receptor-mediated responses

1 reference

11 October 2022

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Mechanism of beta-adrenergic receptor desensitization in cardiac hypertrophy is increased beta-adrenergic receptor kinase

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1161/01.RES.86.1.43

Phosphorylation and desensitization of the human beta 1-adrenergic receptor. Involvement of G protein-coupled receptor kinases and cAMP-dependent protein kinase

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1161/01.RES.86.1.43

Identifiers

DOI

10.1161/01.RES.86.1.43

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24 September 2017

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