Human PC4 is a substrate-specific inhibitor of RNA polymerase II phosphorylation (Q40897870)

24 September 2017

title

Human PC4 is a substrate-specific inhibitor of RNA polymerase II phosphorylation (English)

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24 September 2017

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Schang LM

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24 September 2017

Hwang GJ

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24 September 2017

Dynlacht BD

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24 September 2017

Speicher DW

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24 September 2017

Bantly A

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24 September 2017

Schaffer PA

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24 September 2017

Shilatifard A

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24 September 2017

Ge H

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24 September 2017

Shiekhattar R

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24 September 2017

language of work or name

English

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publication date

1 March 2000

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Journal of Biological Chemistry

24 September 2017

published in

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24 September 2017

volume

275

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24 September 2017

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24 September 2017

page(s)

6071-6074

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Cdk-activating kinase complex is a component of human transcription factor TFIIH

24 September 2017

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Relationship of CDK-activating kinase and RNA polymerase II CTD kinase TFIIH/TFIIK

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An RNA polymerase II transcription factor has an associated DNA-dependent ATPase (dATPase) activity strongly stimulated by the TATA region of promoters

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The MO15 cell cycle kinase is associated with the TFIIH transcription-DNA repair factor

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Association of Cdk-activating kinase subunits with transcription factor TFIIH

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Identification of human cyclin-dependent kinase 8, a putative protein kinase partner for cyclin C

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p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest

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p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21

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The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

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WAF1, a potential mediator of p53 tumor suppression

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Growth suppression by p18, a p16INK4/MTS1- and p14INK4B/MTS2-related CDK6 inhibitor, correlates with wild-type pRb function

21 January 2018

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Isolation and characterization of p19INK4d, a p16-related inhibitor specific to CDK6 and CDK4

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A cell cycle regulator potentially involved in genesis of many tumor types

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A novel mediator of class II gene transcription with homology to viral immediate-early transcriptional regulators

21 January 2018

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Purification, cloning, and characterization of a human coactivator, PC4, that mediates transcriptional activation of class II genes

21 January 2018

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A dynamic model for PC4 coactivator function in RNA polymerase II transcription

21 January 2018

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Interaction of PC4 with melted DNA inhibits transcription

21 January 2018

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C-terminal domain of transcription cofactor PC4 reveals dimeric ssDNA binding site

21 January 2018

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High-affinity DNA binding by the C-terminal domain of the transcriptional coactivator PC4 requires simultaneous interaction with two opposing unpaired strands and results in helix destabilization.

21 January 2018

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Identification of the single-stranded DNA binding surface of the transcriptional coactivator PC4 by NMR.

21 January 2018

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Transcription-positive cofactor 4 forms complexes with HSSB (RPA) on single-stranded DNA and influences HSSB-dependent enzymatic synthesis of simian virus 40 DNA.

21 January 2018

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Inhibition of transcription by the trimeric cyclin-dependent kinase 7 complex

21 January 2018

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Differential regulation of E2F transactivation by cyclin/cdk2 complexes

21 January 2018

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Phosphorylation negatively regulates the function of coactivator PC4

21 January 2018

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An artificial cell-cycle inhibitor isolated from a combinatorial library

21 January 2018

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Dual role of TFIIH in DNA excision repair and in transcription by RNA polymerase II

21 January 2018

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CDKs and cyclins in transition(s).

21 January 2018

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Coactivator PC4 mediates AP-2 transcriptional activity and suppresses ras-induced transformation dependent on AP-2 transcriptional interference

21 January 2018

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DNA repair helicase: a component of BTF2 (TFIIH) basic transcription factor

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.275.9.6071

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24 September 2017

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