Exogenous cdk4 overcomes reduced cdk4 RNA and inhibition of G1 progression in hematopoietic cells expressing a dominant-negative CBF - a model for overcoming inhibition of proliferation by CBF oncoproteins (Q40874612)

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English	Exogenous cdk4 overcomes reduced cdk4 RNA and inhibition of G1 progression in hematopoietic cells expressing a dominant-negative CBF - a model for overcoming inhibition of proliferation by CBF oncoproteins	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

24 September 2017

Exogenous cdk4 overcomes reduced cdk4 RNA and inhibition of G1 progression in hematopoietic cells expressing a dominant-negative CBF - a model for overcoming inhibition of proliferation by CBF oncoproteins (English)

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Europe PubMed Central

PubMed publication ID

24 September 2017

author name string

Lou J

1

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24 September 2017

Cao W

2

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Europe PubMed Central

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24 September 2017

Bernardin F

3

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Europe PubMed Central

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24 September 2017

Ayyanathan K

4

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24 September 2017

RauscherIII FJ

5

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24 September 2017

Friedman AD

6

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24 September 2017

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publication date

1 May 2000

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24 September 2017

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Europe PubMed Central

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24 September 2017

19

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24 September 2017

22

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Europe PubMed Central

PubMed publication ID

24 September 2017

2695-2703

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Europe PubMed Central

PubMed publication ID

24 September 2017

The leukemic protein core binding factor beta (CBFbeta)-smooth-muscle myosin heavy chain sequesters CBFalpha2 into cytoskeletal filaments and aggregates

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Core Binding Factor Cannot Synergistically Activate the Myeloperoxidase Proximal Enhancer in Immature Myeloid Cells without c-Myb

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Failure of embryonic hematopoiesis and lethal hemorrhages in mouse embryos heterozygous for a knocked-in leukemia gene CBFB-MYH11.

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Safe and efficient generation of recombinant retroviruses with amphotropic and ecotropic host ranges

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Both TEL and AML-1 contribute repression domains to the t(12;21) fusion protein

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Aberrant recruitment of the nuclear receptor corepressor-histone deacetylase complex by the acute myeloid leukemia fusion partner ETO.

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Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia

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Identification of CDK4 as a target of c-MYC.

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The t(12;21) translocation converts AML-1B from an activator to a repressor of transcription

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Inhibition of granulocyte differentiation by G1 cyclins D2 and D3 but not D1

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AML1, AML2, and AML3, the human members of the runt domain gene-family: cDNA structure, expression, and chromosomal localization

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Transcriptional repression by AML1 and LEF-1 is mediated by the TLE/Groucho corepressors

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Identification of Putative c-Myc-Responsive Genes: Characterization of rcl, a Novel Growth-Related Gene†

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A modified oestrogen receptor ligand-binding domain as an improved switch for the regulation of heterologous proteins

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Fusion between transcription factor CBF beta/PEBP2 beta and a myosin heavy chain in acute myeloid leukemia

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Acute Myeloid Leukemia with Inv(16) Produces a Chimeric Transcription Factor with a Myosin Heavy Chain Tail

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Identification and properties of an atypical catalytic subunit (p34PSK-J3/cdk4) for mammalian D type G1 cyclins

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Identification of AML-1 and the (8;21) translocation protein (AML-1/ETO) as sequence-specific DNA-binding proteins: the runt homology domain is required for DNA binding and protein-protein interactions

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The t(8;21) fusion protein interferes with AML-1B-dependent transcriptional activation

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Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line

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PEBP2/CBF, the murine homolog of the human myeloid AML1 and PEBP2 beta/CBF beta proto-oncoproteins, regulates the murine myeloperoxidase and neutrophil elastase genes in immature myeloid cells

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The 3;21 translocation in myelodysplasia results in a fusion transcript between the AML1 gene and the gene for EAP, a highly conserved protein associated with the Epstein-Barr virus small RNA EBER 1

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PEBP2/PEA2 represents a family of transcription factors homologous to the products of the Drosophila runt gene and the human AML1 gene

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Molecular cloning and characterization of PEBP2 beta, the heterodimeric partner of a novel Drosophila runt-related DNA binding protein PEBP2 alpha

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AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis

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Indistinguishable nuclear factor binding to functional core sites of the T-cell receptor delta and murine leukemia virus enhancers

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Expression cloning for arsenite-resistance resulted in isolation of tumor-suppressor fau cDNA: possible involvement of the ubiquitin system in arsenic carcinogenesis

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Absence of fetal liver hematopoiesis in mice deficient in transcriptional coactivator core binding factor beta

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Differential regulation of the murine ribosomal protein L26 gene in macrophage activation

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Haploinsufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia

1 reference

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21 January 2018

Expression of the AML-1 oncogene shortens the G(1) phase of the cell cycle

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The murine myeloperoxidase promoter contains several functional elements, one of which binds a cell type-restricted transcription factor, myeloid nuclear factor 1 (MyNF1).

1 reference

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The protooncogene product, PEBP2β/CBFβ, is mainly located in the cytoplasm and has an affinity with cytoskeletal structures

1 reference

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The chimeric protein, PEBP2 beta/CBF beta-SMMHC, disorganizes cytoplasmic stress fibers and inhibits transcriptional activation

1 reference

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Cloning and characterization of subunits of the T-cell receptor and murine leukemia virus enhancer core-binding factor

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Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis

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Embryonic lethality and impairment of haematopoiesis in mice heterozygous for an AML1-ETO fusion gene.

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The C-terminal domain of the largest subunit of RNA polymerase II interacts with a novel set of serine/arginine-rich proteins

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The chimeric genes AML1/MDS1 and AML1/EAP inhibit AML1B activation at the CSF1R promoter, but only AML1/MDS1 has tumor-promoter properties.

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Germline mutations in the p16INK4a binding domain of CDK4 in familial melanoma

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TLE, the Human Homolog of Groucho, Interacts with AML1 and Acts as a Repressor of AML1-Induced Transactivation

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CBFβ-SMMHC, expressed in M4Eo AML, reduced CBF DNA-binding and inhibited the G1 to S cell cycle transition at the restriction point in myeloid and lymphoid cells

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based on heuristic

inferred from DOI database lookup

The core binding factor (CBF) alpha interaction domain and the smooth muscle myosin heavy chain (SMMHC) segment of CBFbeta-SMMHC are both required to slow cell proliferation

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based on heuristic

inferred from DOI database lookup

The fusion gene Cbfb-MYH11 blocks myeloid differentiation and predisposes mice to acute myelomonocytic leukaemia

1 reference

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based on heuristic

inferred from DOI database lookup

The Largest Subunit of Human RNA Polymerase III Is Closely Related to the Largest Subunit of Yeast and Trypanosome RNA Polymerase III

1 reference

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based on heuristic

inferred from DOI database lookup

Steroid receptors and their associated proteins

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

The CBFbeta subunit is essential for CBFalpha2 (AML1) function in vivo

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/SJ.ONC.1203588

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Europe PubMed Central

PubMed publication ID

24 September 2017

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PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

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