RISC is a 5' phosphomonoester-producing RNA endonuclease (Q40840939)

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English	RISC is a 5' phosphomonoester-producing RNA endonuclease	scientific article

Statements

instance of

scholarly article

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stated in

Europe PubMed Central

PMC publication ID

406288

retrieved

24 September 2017

title

RISC is a 5' phosphomonoester-producing RNA endonuclease (English)

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stated in

Europe PubMed Central

PMC publication ID

406288

retrieved

24 September 2017

main subject

endoribonuclease activity, cleaving siRNA-paired mRNA

1 reference

stated in

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:0070551

author

Thomas Tuschl

series ordinal

2

object named as

Thomas Tuschl

1 reference

stated in

Europe PubMed Central

PMC publication ID

406288

retrieved

24 September 2017

author name string

Javier Martinez

series ordinal

1

1 reference

stated in

Europe PubMed Central

PMC publication ID

406288

retrieved

24 September 2017

publication date

22 April 2004

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stated in

Europe PubMed Central

PMC publication ID

406288

retrieved

24 September 2017

published in

Genes & Development

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stated in

Europe PubMed Central

PMC publication ID

406288

retrieved

24 September 2017

volume

18

1 reference

stated in

Europe PubMed Central

PMC publication ID

406288

retrieved

24 September 2017

issue

9

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stated in

Europe PubMed Central

PMC publication ID

406288

retrieved

24 September 2017

page(s)

975-980

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stated in

Europe PubMed Central

PMC publication ID

406288

retrieved

24 September 2017

cites work

Sequence-specific inhibition of small RNA function

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=406288

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24 September 2017

Sequence-specific inhibition of microRNA- and siRNA-induced RNA silencing

1 reference

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PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=406288

retrieved

24 September 2017

Asymmetry in the assembly of the RNAi enzyme complex

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=406288

retrieved

24 September 2017

R2D2, a Bridge Between the Initiation and Effector Steps of the Drosophila RNAi Pathway

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=406288

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24 September 2017

A micrococcal nuclease homologue in RNAi effector complexes

1 reference

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PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=406288

retrieved

24 September 2017

Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing

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PubMed Central

reference URL

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24 September 2017

Killing the messenger: short RNAs that silence gene expression

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PubMed Central

reference URL

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24 September 2017

Structural variations and stabilising modifications of synthetic siRNAs in mammalian cells

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stated in

PubMed Central

reference URL

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24 September 2017

Expression profiling reveals off-target gene regulation by RNAi

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=406288

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24 September 2017

RNAi: an ever-growing puzzle

1 reference

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PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=406288

retrieved

24 September 2017

Similar behaviour of single-strand and double-strand siRNAs suggests they act through a common RNAi pathway

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=406288

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24 September 2017

Tolerance for mutations and chemical modifications in a siRNA.

1 reference

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PubMed Central

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=406288

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24 September 2017

RNA interference: traveling in the cell and gaining functions?

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PubMed Central

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24 September 2017

Human Dicer preferentially cleaves dsRNAs at their termini without a requirement for ATP

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PubMed Central

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24 September 2017

Ribonuclease activity and RNA binding of recombinant human Dicer

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PubMed Central

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=406288

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24 September 2017

Inhibition of HIV-1 infection by small interfering RNA-mediated RNA interference

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PubMed Central

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24 September 2017

Fragile X-related protein and VIG associate with the RNA interference machinery

1 reference

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PubMed Central

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=406288

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24 September 2017

Single-stranded antisense siRNAs guide target RNA cleavage in RNAi

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PubMed Central

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24 September 2017

A microRNA in a multiple-turnover RNAi enzyme complex

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PubMed Central

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24 September 2017

Analysis of gene function in somatic mammalian cells using small interfering RNAs

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PubMed Central

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=406288

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24 September 2017

Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate

1 reference

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PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=406288

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24 September 2017

ATP requirements and small interfering RNA structure in the RNA interference pathway

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=406288

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24 September 2017

Structure and function of type II restriction endonucleases

1 reference

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PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=406288

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24 September 2017

Argonaute2, a link between genetic and biochemical analyses of RNAi

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=406288

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24 September 2017

Spliceosomal UsnRNP biogenesis, structure and function

1 reference

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PubMed Central

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=406288

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24 September 2017

Role for a bidentate ribonuclease in the initiation step of RNA interference

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=406288

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24 September 2017

RNA interference is mediated by 21- and 22-nucleotide RNAs

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=406288

retrieved

24 September 2017

RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=406288

retrieved

24 September 2017

An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells

1 reference

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PubMed Central

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=406288

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24 September 2017

The role of the cleavage site 2'-hydroxyl in the Tetrahymena group I ribozyme reaction

1 reference

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PubMed Central

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24 September 2017

The importance of being ribose at the cleavage site in the Tetrahymena ribozyme reaction

1 reference

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PubMed Central

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=406288

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24 September 2017

siRNA function in RNAi: a chemical modification analysis

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=406288

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15 June 2018

Degradation of tobacco mosaic virus nucleic acid with micrococcal phosphodiesterase

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=406288

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19 August 2018

The purification and properties of micrococcal nuclease.

1 reference

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PubMed Central

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=406288

retrieved

19 August 2018

RNA interference in mammalian cells by chemically-modified RNA.

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=406288

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19 August 2018

Absolute stereochemistry of the second step of ribonuclease action.

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=406288

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19 August 2018

PROTON IONIZATION FROM ADENOSINE

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15105377

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

RNA oligonucleotide synthesis via 5'-silyl-2'-orthoester chemistry

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15105377

retrieved

12 December 2020

based on heuristic

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Multiple magnesium ions in the ribonuclease P reaction mechanism

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15105377

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Action of venom phosphodiesterase on deoxyribonucleic acid

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15105377

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of action of micrococcal nuclease on deoxyribonucleic acid

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stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15105377

retrieved

12 December 2020

based on heuristic

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Identifiers

DOI

10.1101/GAD.1187904

1 reference

stated in

Europe PubMed Central

PMC publication ID

406288

retrieved

24 September 2017

PMC publication ID

406288

1 reference

stated in

Europe PubMed Central

PMC publication ID

406288

retrieved

24 September 2017

PubMed publication ID

15105377

1 reference

stated in

Europe PubMed Central

PMC publication ID

406288

retrieved

24 September 2017

ResearchGate publication ID

8600291

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