SOX9 enhances aggrecan gene promoter/enhancer activity and is up-regulated by retinoic acid in a cartilage-derived cell line, TC6. (Q40831754)

24 September 2017

title

SOX9 enhances aggrecan gene promoter/enhancer activity and is up-regulated by retinoic acid in a cartilage-derived cell line, TC6. (English)

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24 September 2017

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Sekiya I

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24 September 2017

Tsuji K

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24 September 2017

Koopman P

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24 September 2017

Watanabe H

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24 September 2017

Yamada Y

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24 September 2017

Shinomiya K

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24 September 2017

Nifuji A

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24 September 2017

Noda M

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24 September 2017

language of work or name

English

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publication date

1 April 2000

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Journal of Biological Chemistry

24 September 2017

published in

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24 September 2017

volume

275

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24 September 2017

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24 September 2017

page(s)

10738-10744

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Seven new members of the Sox gene family expressed during mouse development

24 September 2017

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SOX9 directly regulates the type-II collagen gene

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SOX9 binds DNA, activates transcription, and coexpresses with type II collagen during chondrogenesis in the mouse

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Parallel expression of Sox9 and Col2a1 in cells undergoing chondrogenesis

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Sox9 is required for cartilage formation

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Mouse cartilage matrix deficiency (cmd) caused by a 7 bp deletion in the aggrecan gene

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Mouse aggrecan, a large cartilage proteoglycan: protein sequence, gene structure and promoter sequence

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21 January 2018

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Retinoic acid rapidly reduces cartilage matrix synthesis by altering gene transcription in chondrocytes.

21 January 2018

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Chondrocyte-specific enhancer elements in the Col11a2 gene resemble the Col2a1 tissue-specific enhancer

21 January 2018

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Sox9 expression during gonadal development implies a conserved role for the gene in testis differentiation in mammals and birds

21 January 2018

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21 January 2018

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A new long form of Sox5 (L-Sox5), Sox6 and Sox9 are coexpressed in chondrogenesis and cooperatively activate the type II collagen gene

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.275.15.10738

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24 September 2017

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