Bcl-2 prevents Bax oligomerization in the mitochondrial outer membrane (Q40816351)

24 September 2017

title

Bcl-2 prevents Bax oligomerization in the mitochondrial outer membrane (English)

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24 September 2017

Mikhailov V

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24 September 2017

Mikhailova M

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24 September 2017

Pulkrabek DJ

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24 September 2017

Dong Z

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24 September 2017

Venkatachalam MA

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24 September 2017

Saikumar P

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24 September 2017

language of work or name

English

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publication date

20 February 2001

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Journal of Biological Chemistry

24 September 2017

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inferred from page(s)

published in

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24 September 2017

volume

276

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24 September 2017

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24 September 2017

page(s)

18361-18374

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Bcl-2 inhibits the mitochondrial release of an apoptogenic protease

24 September 2017

cites work

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Bcl-2 family proteins and mitochondria.

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Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

21 January 2018

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Bax-induced cytochrome C release from mitochondria is independent of the permeability transition pore but highly dependent on Mg2+ ions

21 January 2018

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Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

21 January 2018

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Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

21 January 2018

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Cytosol-to-membrane redistribution of Bax and Bcl-X(L) during apoptosis

21 January 2018

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Bax-induced caspase activation and apoptosis via cytochrome c release from mitochondria is inhibitable by Bcl-xL.

21 January 2018

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Bax directly induces release of cytochrome c from isolated mitochondria

21 January 2018

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Mitochondrial permeability transition is a central coordinating event of apoptosis

21 January 2018

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Preservation of mitochondrial structure and function after Bid- or Bax-mediated cytochrome c release

21 January 2018

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Disruption of the outer mitochondrial membrane as a result of large amplitude swelling: the impact of irreversible permeability transition.

21 January 2018

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Bcl-xL regulates the membrane potential and volume homeostasis of mitochondria

21 January 2018

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The pro-apoptotic proteins, Bid and Bax, cause a limited permeabilization of the mitochondrial outer membrane that is enhanced by cytosol

21 January 2018

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Heterodimerization-independent functions of cell death regulatory proteins Bax and Bcl-2 in yeast and mammalian cells

21 January 2018

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Bax-independent inhibition of apoptosis by Bcl-XL.

21 January 2018

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Bcl-2 family proteins as ion-channels

21 January 2018

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Inhibition of Bax channel-forming activity by Bcl-2

21 January 2018

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Comparison of the ion channel characteristics of proapoptotic BAX and antiapoptotic BCL-2

21 January 2018

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Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis

21 January 2018

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Bax in murine thymus is a soluble monomeric protein that displays differential detergent-induced conformations

21 January 2018

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Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC

21 January 2018

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Bax and adenine nucleotide translocator cooperate in the mitochondrial control of apoptosis

21 January 2018

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Bax, but not Bcl-xL, decreases the lifetime of planar phospholipid bilayer membranes at subnanomolar concentrations

21 January 2018

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Immortalization and characterization of proximal tubule cells derived from kidneys of spontaneously hypertensive and normotensive rats

21 January 2018

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Glycine attenuates Fanconi syndrome induced by maleate or ifosfamide in rats

21 January 2018

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Renal epithelial amino acid concentrations in mercury-induced and postischemic acute renal failure

21 January 2018

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The cytoskeleton of digitonin-treated rat hepatocytes

21 January 2018

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BAX-dependent transport of cytochrome c reconstituted in pure liposomes

21 January 2018

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Bcl-2 inhibits Bax translocation from cytosol to mitochondria during drug-induced apoptosis of human tumor cells.

21 January 2018

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Interleukin-3 induces the phosphorylation of a distinct fraction of bcl-2.

21 January 2018

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The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100655200

Bax oligomerization is required for channel-forming activity in liposomes and to trigger cytochrome c release from mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100655200

Bax membrane insertion during Fas(CD95)-induced apoptosis precedes cytochrome c release and is inhibited by Bcl-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100655200

21 January 2018

Identifiers

DOI

10.1074/JBC.M100655200

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24 September 2017

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