Inhibition of PI3-kinase sensitises HL60 human leukaemia cells to both chemotherapeutic drug- and Fas-induced apoptosis by a JNK independent pathway. (Q40787984)

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English	Inhibition of PI3-kinase sensitises HL60 human leukaemia cells to both chemotherapeutic drug- and Fas-induced apoptosis by a JNK independent pathway.	scientific article

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11489474%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

Inhibition of PI3-kinase sensitises HL60 human leukaemia cells to both chemotherapeutic drug- and Fas-induced apoptosis by a JNK independent pathway (English)

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Europe PubMed Central

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10 November 2019

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Sharon L McKenna

2

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10 November 2019

Thomas G Cotter

4

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10 November 2019

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D M O'Gorman

1

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10 November 2019

A J McGahon

3

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10 November 2019

publication date

1 September 2001

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10 November 2019

Leukemia Research

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10 November 2019

25

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10 November 2019

9

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10 November 2019

801-811

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10 November 2019

Sensitisation of HL60 human leukaemic cells to cytotoxic drug-induced apoptosis by inhibition of PI3-kinase survival signals.

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2801%2900024-8

7 January 2021

based on heuristic

inferred from DOI database lookup

PI3K: downstream AKTion blocks apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2801%2900024-8

7 January 2021

based on heuristic

inferred from DOI database lookup

CD95(APO-1/Fas)-mediated apoptosis: live and let die

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2801%2900024-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Chemotherapeutic drugs sensitize pre-B ALL cells for CD95- and cytotoxic T-lymphocyte-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2801%2900024-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Involvement of the CD95 (APO–1/Fas) receptor/ligand system in drug–induced apoptosis in leukemia cells

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2801%2900024-8

7 January 2021

based on heuristic

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Activation of SAPK/JNK by camptothecin sensitizes androgen-independent prostate cancer cells to Fas-induced apoptosis.

1 reference

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7 January 2021

based on heuristic

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Deficient activation of the CD95 (APO-1/Fas) system in drug-resistant cells

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2801%2900024-8

7 January 2021

based on heuristic

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DNA damaging agents induce expression of Fas ligand and subsequent apoptosis in T lymphocytes via the activation of NF-kappa B and AP-1.

1 reference

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7 January 2021

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Drug-induced apoptosis in hepatoma cells is mediated by the CD95 (APO-1/Fas) receptor/ligand system and involves activation of wild-type p53.

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2801%2900024-8

7 January 2021

based on heuristic

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The stress-activated protein kinase pathways

1 reference

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7 January 2021

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c-Jun NH2-terminal kinase-mediated activation of interleukin-1beta converting enzyme/CED-3-like protease during anticancer drug-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2801%2900024-8

7 January 2021

based on heuristic

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Withdrawal of survival factors results in activation of the JNK pathway in neuronal cells leading to Fas ligand induction and cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2801%2900024-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Protection of CD95-mediated apoptosis by activation of phosphatidylinositide 3-kinase and protein kinase B

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2801%2900024-8

7 January 2021

based on heuristic

inferred from DOI database lookup

PKB/Akt: connecting phosphoinositide 3-kinase to cell survival and beyond

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2801%2900024-8

7 January 2021

based on heuristic

inferred from DOI database lookup

All-trans-retinoic acid inhibits Jun N-terminal kinase-dependent signaling pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2801%2900024-8

7 January 2021

based on heuristic

inferred from DOI database lookup

A Bad kinase makes good

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2801%2900024-8

7 January 2021

based on heuristic

inferred from DOI database lookup

JNK activation is not required for Fas-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2801%2900024-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Regulation of cell death protease caspase-9 by phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2801%2900024-8

7 January 2021

based on heuristic

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Wortmannin enhances activation of CPP32 (Caspase-3) induced by TNF or anti-Fas

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2801%2900024-8

7 January 2021

based on heuristic

inferred from DOI database lookup

FLICE is activated by association with the CD95 death-inducing signaling complex (DISC).

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2801%2900024-8

7 January 2021

based on heuristic

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NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2801%2900024-8

7 January 2021

based on heuristic

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NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2801%2900024-8

7 January 2021

based on heuristic

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NF-kappaB to the rescue: RELs, apoptosis and cellular transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2801%2900024-8

7 January 2021

based on heuristic

inferred from DOI database lookup

NF-kappaB induces expression of the Bcl-2 homologue A1/Bfl-1 to preferentially suppress chemotherapy-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2801%2900024-8

7 January 2021

based on heuristic

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NF-kappaB-mediated up-regulation of Bcl-x and Bfl-1/A1 is required for CD40 survival signaling in B lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2801%2900024-8

7 January 2021

based on heuristic

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Suppression of tumor necrosis factor-induced cell death by inhibitor of apoptosis c-IAP2 is under NF-kappaB control

1 reference

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7 January 2021

based on heuristic

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TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB

1 reference

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7 January 2021

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NFkappaB mediates apoptosis through transcriptional activation of Fas (CD95) in adenoviral hepatitis

1 reference

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7 January 2021

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The molecular pathophysiology of myeloid leukaemias: Ras revisited.

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7 January 2021

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Transfection by human oncogenes: concomitant induction of tumorigenicity and tumor-associated membrane alterations

1 reference

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7 January 2021

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Identification of transforming gene in two human sarcoma cell lines as a new member of the ras gene family located on chromosome 1.

1 reference

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7 January 2021

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The activation of phosphatidylinositol 3-kinase by Ras

1 reference

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7 January 2021

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1 reference

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Identifiers

10.1016/S0145-2126(01)00024-8

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11489474%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11489474%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

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