Activation of the transcription factor NF-kappaB by the erythropoietin receptor: structural requirements and biological significance (Q40787375)

23 September 2017

title

Activation of the transcription factor NF-kappaB by the erythropoietin receptor: structural requirements and biological significance (English)

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23 September 2017

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Bittorf T

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23 September 2017

Büchse T

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23 September 2017

Sasse T

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23 September 2017

Jaster R

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23 September 2017

Brock J

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23 September 2017

publication date

1 September 2001

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23 September 2017

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inferred from page(s)

published in

Cellular Signalling

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23 September 2017

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23 September 2017

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23 September 2017

page(s)

673-681

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Structural design and molecular evolution of a cytokine receptor superfamily

23 September 2017

cites work

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7 January 2021

JAK2 associates with the erythropoietin receptor and is tyrosine phosphorylated and activated following stimulation with erythropoietin

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7 January 2021

Jak2 is essential for signaling through a variety of cytokine receptors

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7 January 2021

Lyn tyrosine kinase is essential for erythropoietin-induced differentiation of J2E erythroid cells

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7 January 2021

Cytokine receptor signalling

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7 January 2021

Tyrosine 343 in the erythropoietin receptor positively regulates erythropoietin-induced cell proliferation and Stat5 activation.

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7 January 2021

Multiple tyrosine residues in the cytosolic domain of the erythropoietin receptor promote activation of STAT5.

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7 January 2021

Identification of tyrosine residues within the intracellular domain of the erythropoietin receptor crucial for STAT5 activation

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7 January 2021

Erythropoietin induces activation of Stat5 through association with specific tyrosines on the receptor that are not required for a mitogenic response.

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7 January 2021

Phosphorylation of tyrosine 503 in the erythropoietin receptor (EpR) is essential for binding the P85 subunit of phosphatidylinositol (PI) 3-kinase and for EpR-associated PI 3-kinase activity

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7 January 2021

Identification of a novel pathway important for proliferation and differentiation of primary erythroid progenitors

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7 January 2021

Specific recruitment of SH-PTP1 to the erythropoietin receptor causes inactivation of JAK2 and termination of proliferative signals

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7 January 2021

Involvement of SH2-containing phosphotyrosine phosphatase Syp in erythropoietin receptor signal transduction pathways

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7 January 2021

STAT5 activation correlates with erythropoietin receptor-mediated erythroid differentiation of an erythroleukemia cell line.

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7 January 2021

A possible involvement of Stat5 in erythropoietin-induced hemoglobin synthesis

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7 January 2021

Prevention of apoptosis in J2E erythroid cells by erythropoietin: involvement of JAK2 but not MAP kinases.

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7 January 2021

Activation of STAT5 during EPO-directed suppression of apoptosis

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Fetal anemia and apoptosis of red cell progenitors in Stat5a-/-5b-/- mice: a direct role for Stat5 in Bcl-X(L) induction

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7 January 2021

The Rel/NF-kappaB family directly activates expression of the apoptosis inhibitor Bcl-x(L).

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7 January 2021

The NF-kappa B and I kappa B proteins: new discoveries and insights

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How NF-kappaB is activated: the role of the IkappaB kinase (IKK) complex

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7 January 2021

Multiple nuclear factors interact with the immunoglobulin enhancer sequences

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The combined absence of the transcription factors Rel and RelA leads to multiple hemopoietic cell defects

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7 January 2021

Evidence for a role of NF-kappaB in the survival of hematopoietic cells mediated by interleukin 3 and the oncogenic TEL/platelet-derived growth factor receptor beta fusion protein

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7 January 2021

Il-3-dependent mouse clones that express B-220 surface antigen, contain Ig genes in germ-line configuration, and generate B lymphocytes in vivo.

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7 January 2021

Constitutive synthesis of interleukin-3 by leukaemia cell line WEHI-3B is due to retroviral insertion near the gene

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7 January 2021

A rapid and simple method for the isolation of apoptotic DNA fragments.

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A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells

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7 January 2021

JAK2 is required for induction of the murine DUB-1 gene

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7 January 2021

SHP1 protein tyrosine phosphatase negatively modulates erythroid differentiation and suppression of apoptosis in J2E erythroleukemic cells

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7 January 2021

The cytoplasmic region of the erythropoietin receptor contains nonoverlapping positive and negative growth-regulatory domains

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7 January 2021

Erythropoietin receptor signals both proliferation and erythroid-specific differentiation

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7 January 2021

Ligand-induced activation of chimeric receptors between the erythropoietin receptor and receptor tyrosine kinases

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7 January 2021

Activators and target genes of Rel/NF-kappaB transcription factors

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7 January 2021

The regulation and roles of Rel/NF-kappa B transcription factors during lymphocyte activation

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7 January 2021

Phosphatidylinositol 3-kinase in interleukin 1 signaling. Physical interaction with the interleukin 1 receptor and requirement in NFkappaB and AP-1 activation

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7 January 2021

Wortmannin inhibits activation of nuclear transcription factors NF-kappaB and activated protein-1 induced by lipopolysaccharide and phorbol ester

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7 January 2021

Cytokine-inducible SH2 protein-3 (CIS3/SOCS3) inhibits Janus tyrosine kinase by binding through the N-terminal kinase inhibitory region as well as SH2 domain

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7 January 2021

Involvement of Phosphatidylinositol 3-Kinase in the Mediation of Erythropoietin-Induced Activation of p70S6k

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7 January 2021

Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-κB

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7 January 2021

Inhibition of TNF-induced apoptosis by NF-kappa B.

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7 January 2021

Evidence that de novo protein synthesis is dispensable for anti-apoptotic effects of NF-kappaB.

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7 January 2021

10.1016/S0898-6568(01)00189-9

Identifiers

DOI

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23 September 2017

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