DNA damage invokes mismatch repair-dependent cyclin D1 attenuation and retinoblastoma signaling pathways to inhibit CDK2. (Q40765943)

23 September 2017

title

DNA damage invokes mismatch repair-dependent cyclin D1 attenuation and retinoblastoma signaling pathways to inhibit CDK2. (English)

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23 September 2017

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Zvjezdana Sever-Chroneos

object named as

Zvjezdana Sever-Chroneos

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23 September 2017

Zhengdao Lan

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23 September 2017

Matthew W Strobeck

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23 September 2017

Chi-Hyun Park

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23 September 2017

R Baskaran

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23 September 2017

Winfried Edelmann

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23 September 2017

Gustavo Leone

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23 September 2017

Erik S Knudsen

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23 September 2017

language of work or name

English

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publication date

28 November 2001

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Journal of Biological Chemistry

23 September 2017

published in

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23 September 2017

volume

277

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23 September 2017

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23 September 2017

page(s)

8372-8381

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Cell cycle checkpoints: preventing an identity crisis

23 September 2017

cites work

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Cdk phosphorylation triggers sequential intramolecular interactions that progressively block Rb functions as cells move through G1

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Control of pRB phosphorylation

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Functional inactivation of the retinoblastoma protein requires sequential modification by at least two distinct cyclin-cdk complexes

21 January 2018

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The regulation of E2F by pRB-family proteins

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Role of the Rb/E2F pathway in cell growth control

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p21 is a critical CDK2 regulator essential for proliferation control in Rb-deficient cells

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pRB plays an essential role in cell cycle arrest induced by DNA damage

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RB-dependent S-phase response to DNA damage

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Mismatch repair: mechanisms and relationship to cancer susceptibility

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DNA chaperones: a solution to a persistence problem?

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Identification of mismatch repair genes and their role in the development of cancer

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Tumour susceptibility and spontaneous mutation in mice deficient in Mlh1, Pms1 and Pms2 DNA mismatch repair

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Cisplatin and adriamycin resistance are associated with MutLalpha and mismatch repair deficiency in an ovarian tumor cell line

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Induction of JNK and c-Abl signalling by cisplatin and oxaliplatin in mismatch repair-proficient and -deficient cells

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Cyclin D1 is dispensable for G1 control in retinoblastoma gene-deficient cells independently of cdk4 activity.

21 January 2018

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The p21(Cip1) and p27(Kip1) CDK 'inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblasts

21 January 2018

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Requirement of cyclin E-Cdk2 inhibition in p16(INK4a)-mediated growth suppression

21 January 2018

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Induced expression of p16(INK4a) inhibits both CDK4- and CDK2-associated kinase activity by reassortment of cyclin-CDK-inhibitor complexes

21 January 2018

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21 January 2018

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21 January 2018

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Distinct Initiation and Maintenance Mechanisms Cooperate to Induce G1 Cell Cycle Arrest in Response to DNA Damage

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21 January 2018

Identifiers

DOI

10.1074/JBC.M108906200

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23 September 2017

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