Biochemical and biological properties of the human N-ras p21 protein (Q40658346)

22 September 2017

Biochemical and biological properties of the human N-ras p21 protein (English)

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22 September 2017

Trahey M

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22 September 2017

Milley RJ

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22 September 2017

Cole GE

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22 September 2017

Innis M

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22 September 2017

Paterson H

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22 September 2017

Marshall CJ

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22 September 2017

Hall A

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22 September 2017

McCormick F

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22 September 2017

language of work or name

English

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publication date

1 January 1987

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Molecular and Cellular Biology

22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

541-544

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Protein measurement with the Folin phenol reagent

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365100

A point mutation is responsible for the acquisition of transforming properties by the T24 human bladder carcinoma oncogene

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365100

Acquisition of transforming properties by alternative point mutations within c-bas/has human proto-oncogene

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365100

Three human transforming genes are related to the viral ras oncogenes

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365100

Guanosine nucleotide binding by highly purified Ha-ras-encoded p21 protein produced in Escherichia coli.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365100

Analysis of the transforming potential of the human H-ras gene by random mutagenesis

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365100

Structure of the Ki-ras gene of the human lung carcinoma cell line Calu-1.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365100

Mechanism of activation of a human oncogene

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365100

Transforming genes of human bladder and lung carcinoma cell lines are homologous to the ras genes of Harvey and Kirsten sarcoma viruses

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365100

T24 human bladder carcinoma oncogene is an activated form of the normal human homologue of BALB- and Harvey-MSV transforming genes

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365100

Human EJ bladder carcinoma oncogene is homologue of Harvey sarcoma virus ras gene

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365100

Intrinsic GTPase activity distinguishes normal and oncogenic ras p21 molecules

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365100

Human Colon Carcinoma Ki-ras2 Oncogene and Its Corresponding Proto-Oncogene

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365100

Site-specific mutagenesis of the human fibroblast interferon gene

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365100

Purification and characterization of human H-ras proteins expressed in Escherichia coli

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365100

Activation of an N-ras gene in acute myeloblastic leukemia through somatic mutation in the first exon

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365100

Biochemical characterization of polypeptides encoded by mutated human Ha-ras1 genes

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365100

Mutant ras-encoded proteins with altered nucleotide binding exert dominant biological effects

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365100

Biochemical properties of a highly purified v-rasH p21 protein overproduced in Escherichia coli and inhibition of its activities by a monoclonal antibody

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365100

Human N-ras: cDNA cloning and gene structure

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365100

Amino-acid substitutions at codon 13 of the N-ras oncogene in human acute myeloid leukaemia

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365100

Ha-ras proteins exhibit GTPase activity: point mutations that activate Ha-ras gene products result in decreased GTPase activity

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365100

Transformation of NIH 3T3 cells by microinjection of Ha-ras p21 protein

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365100

Activation of Ki-ras2 gene in human colon and lung carcinomas by two different point mutations

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365100

Guanine nucleotide-binding and autophosphorylating activities associated with the p21src protein of Harvey murine sarcoma virus

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365100

Comparative biochemical properties of normal and activated human ras p21 protein

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365100

Biological and biochemical properties of human rasH genes mutated at codon 61.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365100

Ras p21 proteins with high or low GTPase activity can efficiently transform NIH/3T3 cells

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365100

Viral Harvey ras p21 expressed in Escherichia coli purifies as a binary one-to-one complex with GDP.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365100

Guanine nucleotide binding activity of the src gene product of rat-derived murine sarcoma viruses.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365100

The product of ras is a GTPase and the T24 oncogenic mutant is deficient in this activity.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365100

The oncogenic activation of human p21ras by a novel mechanism

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365100

Catalytic properties of the SV40 large T antigen

19 August 2018

1 reference

12 December 2020

30 Microinjection of tissue culture cells

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12 December 2020

Microinjection of the oncogene form of the human H-ras (T-24) protein results in rapid proliferation of quiescent cells

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12 December 2020

p21ras. Heterogeneous localization in transformed cells

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12 December 2020

Identifiers

DOI

10.1128/MCB.7.1.541

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22 September 2017

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22 September 2017

PubMed publication ID

3550423

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