Expression of constitutively activated Akt in the mammary gland leads to excess lipid synthesis during pregnancy and lactation (Q40654612)

22 September 2017

title

Expression of constitutively activated Akt in the mammary gland leads to excess lipid synthesis during pregnancy and lactation (English)

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22 September 2017

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12700340

25 December 2023

1 reference

https://api.crossref.org/works/10.1194/JLR.M300045-JLR200

25 December 2023

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https://api.crossref.org/works/10.1194/JLR.M300045-JLR200

25 December 2023

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https://api.crossref.org/works/10.1194/JLR.M300045-JLR200

25 December 2023

author

Kathryn L Schwertfeger

object named as

Kathryn L Schwertfeger

1 reference

22 September 2017

James L. McManaman

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12700340

25 December 2023

Carol A. Palmer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12700340

25 December 2023

Margaret C. Neville

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12700340

25 December 2023

Steven M. Anderson

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12700340

25 December 2023

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12700340

25 December 2023

publication date

16 April 2003

1 reference

full work available at URL

22 September 2017

http://www.jlr.org/content/44/6/1100.full.pdf

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12700340

https://api.elsevier.com/content/article/PII:S0022227520311111?httpAccept=text/xml

25 December 2023

1 reference

https://api.crossref.org/works/10.1194/JLR.M300045-JLR200

https://api.elsevier.com/content/article/PII:S0022227520311111?httpAccept=text/plain

25 December 2023

1 reference

https://api.crossref.org/works/10.1194/JLR.M300045-JLR200

https://syndication.highwire.org/content/doi/10.1194/jlr.M300045-JLR200

25 December 2023

1 reference

https://api.crossref.org/works/10.1194/JLR.M300045-JLR200

Journal of Lipid Research

25 December 2023

published in

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22 September 2017

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22 September 2017

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22 September 2017

page(s)

1100-1112

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Activation of Stat5a and Stat5b by tyrosine phosphorylation is tightly linked to mammary gland differentiation.

22 September 2017

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Functional regulation of xanthine oxidoreductase expression and localization in the mouse mammary gland: evidence of a role in lipid secretion

21 January 2018

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Antibodies to the major insoluble milk fat globule membrane-associated protein: specific location in apical regions of lactating epithelial cells

21 January 2018

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Localization of xanthine oxidase in mammary-gland epithelium and capillary endothelium

21 January 2018

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Adipocyte differentiation-related protein is secreted into milk as a constituent of milk lipid globule membrane

21 January 2018

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Golgi targeting of the GLUT1 glucose transporter in lactating mouse mammary gland

21 January 2018

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Identification and characterization of glucose transport proteins in plasma membrane- and Golgi vesicle-enriched fractions prepared from lactating rat mammary gland

21 January 2018

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The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal.

21 January 2018

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Lack of correlation between activation of Jun-NH2-terminal kinase and induction of apoptosis after detachment of epithelial cells

21 January 2018

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Akt/Protein kinase B inhibits cell death by preventing the release of cytochrome c from mitochondria

21 January 2018

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Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB.

21 January 2018

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Epidermal growth factor protects epithelial cells against Fas-induced apoptosis. Requirement for Akt activation

21 January 2018

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Cellular survival: a play in three Akts

21 January 2018

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Expression of a constitutively active Akt Ser/Thr kinase in 3T3-L1 adipocytes stimulates glucose uptake and glucose transporter 4 translocation

21 January 2018

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Expression of a constitutively activated form of protein kinase B (c-Akt) in 3T3-L1 preadipose cells causes spontaneous differentiation

21 January 2018

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Regulation of GLUT1 gene transcription by the serine/threonine kinase Akt1.

21 January 2018

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Protein kinase B stimulates the translocation of GLUT4 but not GLUT1 or transferrin receptors in 3T3-L1 adipocytes by a pathway involving SNAP-23, synaptobrevin-2, and/or cellubrevin

21 January 2018

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Opposite translational control of GLUT1 and GLUT4 glucose transporter mRNAs in response to insulin. Role of mammalian target of rapamycin, protein kinase b, and phosphatidylinositol 3-kinase in GLUT1 mRNA translation

21 January 2018

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Regulation of neuronal survival by the serine-threonine protein kinase Akt

21 January 2018

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IKKalpha provides an essential link between RANK signaling and cyclin D1 expression during mammary gland development

21 January 2018

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The osteoclast differentiation factor osteoprotegerin-ligand is essential for mammary gland development

21 January 2018

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Phosphatidylinositol 3-Kinase Is Required for Integrin-Stimulated AKT and Raf-1/Mitogen-Activated Protein Kinase Pathway Activation

21 January 2018

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Mammary gland involution is delayed by activated Akt in transgenic mice.

21 January 2018

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Activation of Akt (protein kinase B) in mammary epithelium provides a critical cell survival signal required for tumor progression

21 January 2018

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Quantitation of adipose conversion and triglycerides by staining intracytoplasmic lipids with Oil red O.

21 January 2018

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Adipophilin is a specific marker of lipid accumulation in diverse cell types and diseases

21 January 2018

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Transgenic mice expressing recombinant human protein C exhibit defects in lactation and impaired mammary gland development

21 January 2018

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Sodium dependence of nitrofurantoin active transport across mammary epithelia and effects of dipyridamole, nucleosides, and nucleobases

21 January 2018

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Epithelial mouse mammary cell line exhibiting normal morphogenesis in vivo and functional differentiation in vitro.

21 January 2018

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Defective mammopoiesis, but normal hematopoiesis, in mice with a targeted disruption of the prolactin gene

21 January 2018

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Null mutation of the prolactin receptor gene produces multiple reproductive defects in the mouse

21 January 2018

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Mice lacking progesterone receptor exhibit pleiotropic reproductive abnormalities

21 January 2018

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A mutation in the epidermal growth factor receptor in waved-2 mice has a profound effect on receptor biochemistry that results in impaired lactation

21 January 2018

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Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt.

21 January 2018

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Fibroblast growth factor (FGF) signaling through PI 3-kinase and Akt/PKB is required for embryoid body differentiation

21 January 2018

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Stat5a is mandatory for adult mammary gland development and lactogenesis.

21 January 2018

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HIF1alpha is a critical regulator of secretory differentiation and activation, but not vascular expansion, in the mouse mammary gland

21 January 2018

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Mammary-derived signals activate programmed cell death during the first stage of mammary gland involution

21 January 2018

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Deletion of Stat3 blocks mammary gland involution and extends functional competence of the secretory epithelium in the absence of lactogenic stimuli.

21 January 2018

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Identification of wortmannin-sensitive targets in 3T3-L1 adipocytes. DissociationoOf insulin-stimulated glucose uptake and glut4 translocation.

21 January 2018

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Expression and localisation of GLUT1 and GLUT12 glucose transporters in the pregnant and lactating rat mammary gland.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Protein kinase expression during murine mammary development

25 December 2023

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Phosphatidylinositol 3-kinase and Akt protein kinase are necessary and sufficient for the survival of nerve growth factor-dependent sympathetic neurons.

25 December 2023

1 reference

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Mechanism of activation of protein kinase B by insulin and IGF-1

25 December 2023

1 reference

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Activation of growth hormone receptor delivers an antiapoptotic signal: evidence for a role of Akt in this pathway

25 December 2023

1 reference

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Possible role for protein kinase B in the anti-apoptotic effect of prolactin in rat Nb2 lymphoma cells

25 December 2023

1 reference

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Delayed mammary gland involution in MMTV-AKT1 transgenic mice

25 December 2023

1 reference

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Prolactin stimulates activation of c-jun N-terminal kinase (JNK).

25 December 2023

1 reference

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Localization of the GLUT1 glucose transporter to brefeldin A-sensitive vesicles of differentiated CIT3 mouse mammary epithelial cells

25 December 2023

1 reference

https://api.crossref.org/works/10.1194/JLR.M300045-JLR200

Hormonal regulation of the glucose transporter GLUT I in the lactating rat mammary gland

25 December 2023

1 reference

https://api.crossref.org/works/10.1194/JLR.M300045-JLR200

Hormonal control of lipid metabolism in mouse mammary gland explants

25 December 2023

1 reference

https://api.crossref.org/works/10.1194/JLR.M300045-JLR200

25 December 2023

Identifiers

1 reference

22 September 2017

1 reference