The MEK/ERK pathway acts upstream of NF kappa B1 (p50) homodimer activity and Bcl-2 expression in a murine B-cell lymphoma cell line. MEK inhibition restores radiation-induced apoptosis (Q40640417)

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scientific article published on 11 June 2003

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English	The MEK/ERK pathway acts upstream of NF kappa B1 (p50) homodimer activity and Bcl-2 expression in a murine B-cell lymphoma cell line. MEK inhibition restores radiation-induced apoptosis	scientific article published on 11 June 2003

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

The MEK/ERK pathway acts upstream of NF kappa B1 (p50) homodimer activity and Bcl-2 expression in a murine B-cell lymphoma cell line. MEK inhibition restores radiation-induced apoptosis (English)

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

B-cell lymphoma

1 reference

based on heuristic

inferred from title

author name string

John F Kurland

1

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

David W Voehringer

2

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

Raymond E Meyn

3

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

language of work or name

0 references

publication date

11 June 2003

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Europe PubMed Central

PubMed publication ID

22 September 2017

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

22 September 2017

278

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Europe PubMed Central

PubMed publication ID

22 September 2017

34

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

32465-32470

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

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Activators and target genes of Rel/NF-kappaB transcription factors

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The role of NF-kappaB/IkappaB proteins in cancer: implications for novel treatment strategies

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Aberrant rel/nfkb genes and activity in human cancer

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Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity

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Identification and characterization of an IkappaB kinase

1 reference

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Activation of the IkappaB alpha kinase complex by MEKK1, a kinase of the JNK pathway

1 reference

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21 January 2018

Differential regulation of IkappaB kinase alpha and beta by two upstream kinases, NF-kappaB-inducing kinase and mitogen-activated protein kinase/ERK kinase kinase-1

1 reference

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21 January 2018

Mitogen-activated protein kinase/ERK kinase kinases 2 and 3 activate nuclear factor-kappaB through IkappaB kinase-alpha and IkappaB kinase-beta

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1 reference

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The ups and downs of MEK kinase interactions

1 reference

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ERK5 and ERK2 cooperate to regulate NF-kappaB and cell transformation

1 reference

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Induction of beta-transducin repeat-containing protein by JNK signaling and its role in the activation of NF-kappaB.

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NF-kappaB1 (p50) homodimers contribute to transcription of the bcl-2 oncogene

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Specificity and mechanism of action of some commonly used protein kinase inhibitors

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Activation of the protein kinase ERK5/BMK1 by receptor tyrosine kinases. Identification and characterization of a signaling pathway to the nucleus

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21 January 2018

Cell-cycle arrest by PD184352 requires inhibition of extracellular signal-regulated kinases (ERK) 1/2 but not ERK5/BMK1.

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21 January 2018

Transcriptional regulation of bcl-2 by nuclear factor kappa B and its significance in prostate cancer

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21 January 2018

NF-kappaB activates Bcl-2 expression in t(14;18) lymphoma cells

1 reference

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21 January 2018

Bcl-2 activates the transcription factor NFkappaB through the degradation of the cytoplasmic inhibitor IkappaBalpha

1 reference

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21 January 2018

Linkage of the BH4 domain of Bcl-2 and the nuclear factor kappaB signaling pathway for suppression of apoptosis

1 reference

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Regulation of NFKB1 proteins by the candidate oncoprotein BCL-3: generation of NF-kappa B homodimers from the cytoplasmic pool of p50-p105 and nuclear translocation

1 reference

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21 January 2018

The bcl-3 proto-oncogene encodes a nuclear I kappa B-like molecule that preferentially interacts with NF-kappa B p50 and p52 in a phosphorylation-dependent manner

1 reference

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21 January 2018

Constitutive expression of Bc1-3 in thymocytes increases the DNA binding of NF-kappaB1 (p50) homodimers in vivo

1 reference

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21 January 2018

NF-kappaB p105 is a target of IkappaB kinases and controls signal induction of Bcl-3-p50 complexes

1 reference

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21 January 2018

Synergistic induction of apoptosis by simultaneous disruption of the Bcl-2 and MEK/MAPK pathways in acute myelogenous leukemia

1 reference

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21 January 2018

Cytotoxicity induced by manipulation of signal transduction pathways is associated with down-regulation of Bcl-2 but not Mcl-1 in MCF-7 human breast cancer

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21 January 2018

Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo

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Unraveling the complexities of the Raf/MAP kinase pathway for pharmacological intervention

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21 January 2018

MEK/ERK pathway protects ionizing radiation-induced loss of mitochondrial membrane potential and cell death in lymphocytic leukemia cells

1 reference

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TPL-2 kinase regulates the proteolysis of the NF-kappaB-inhibitory protein NF-kappaB1 p105

1 reference

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21 January 2018

Identifiers

10.1074/JBC.M212919200

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

ResearchGate publication ID

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