Curcumin (Diferuloylmethane) Inhibits Constitutive and IL-6-Inducible STAT3 Phosphorylation in Human Multiple Myeloma Cells (Q40633129)

22 September 2017

title

Curcumin (diferuloylmethane) inhibits constitutive and IL-6-inducible STAT3 phosphorylation in human multiple myeloma cells (English)

1 reference

22 September 2017

Curcumin (Diferuloylmethane) Inhibits Constitutive and IL-6-Inducible STAT3 Phosphorylation in Human Multiple Myeloma Cells (English)

1 reference

Crossref

DOI

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3863

12 March 2024

0 references

1 reference

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https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3863

12 March 2024

Nicholas Donato

1 reference

22 September 2017

Alok C. Bharti

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14500688

12 March 2024

Bharat B. Aggarwal

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14500688

12 March 2024

language of work or name

English

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publication date

1 October 2003

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full work available at URL

22 September 2017

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inferred from page(s)

published in

Journal of Immunology

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22 September 2017

volume

171

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22 September 2017

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22 September 2017

page(s)

3863-3871

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Diagnosis and management of multiple myeloma

22 September 2017

cites work

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Autocrine generation and requirement of BSF-2/IL-6 for human multiple myelomas

12 March 2024

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Stat3 activation is required for cellular transformation by v-src

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Stat3 activation by Src induces specific gene regulation and is required for cell transformation

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Proliferation of adult T cell leukemia/lymphoma cells is associated with the constitutive activation of JAK/STAT proteins

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Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells

12 March 2024

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Regulation of Bcl-xL: a little bit of this and a little bit of STAT.

12 March 2024

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Curcumin (diferuloylmethane) down-regulates the constitutive activation of nuclear factor-kappa B and IkappaBalpha kinase in human multiple myeloma cells, leading to suppression of proliferation and induction of apoptosis

12 March 2024

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12 March 2024

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Signals through gp130 upregulate bcl-x gene expression via STAT1-binding cis-element in cardiac myocytes.

12 March 2024

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Characteristics of established myeloma and lymphoblastoid cell lines derived from an E myeloma patient: a comparative study.

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Phosphotyrosyl peptides block Stat3-mediated DNA binding activity, gene regulation, and cell transformation

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TNF and IL-6 are potent growth factors for OH-2, a novel human myeloma cell line.

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Production of lymphotoxin, a bone-resorbing cytokine, by cultured human myeloma cells

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Curcumin inhibits experimental allergic encephalomyelitis by blocking IL-12 signaling through Janus kinase-STAT pathway in T lymphocytes

12 March 2024

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Oncostatin M-induced matrix metalloproteinase and tissue inhibitor of metalloproteinase-3 genes expression in chondrocytes requires Janus kinase/STAT signaling pathway

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IL-6 mediated activation of STAT3 bypasses Janus kinases in terminally differentiated B lineage cells

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Activation of STAT3 by the Src family kinase Hck requires a functional SH3 domain

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Activation of Stat3 preassembled with platelet-derived growth factor beta receptors requires Src kinase activity

12 March 2024

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Protein kinase C delta associates with and phosphorylates Stat3 in an interleukin-6-dependent manner

12 March 2024

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12 March 2024

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Curcumin is a non-competitive and selective inhibitor of phosphorylase kinase

12 March 2024

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12 March 2024

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12 March 2024

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12 March 2024

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SOCS-1, a negative regulator of cytokine signaling, is frequently silenced by methylation in multiple myeloma

12 March 2024

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Role of curcumin in idiopathic inflammatory orbital pseudotumours

12 March 2024

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Efficacy of curcumin in the management of chronic anterior uveitis

12 March 2024

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12 March 2024

Identifiers

DOI

1 reference

22 September 2017

1 reference