A serine protease is involved in the initiation of DNA damage-induced apoptosis (Q40632732)

22 September 2017

title

A serine protease is involved in the initiation of DNA damage-induced apoptosis (English)

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22 September 2017

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https://api.crossref.org/works/10.1038/SJ.CDD.4401296

12 March 2024

J. P. Medema

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12 March 2024

den Otter I

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22 September 2017

Peltenburg LT

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22 September 2017

E. C. de Bruin

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12 March 2024

D. Meersma

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J. de Wilde

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12 March 2024

I. den Otter

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12 March 2024

E. M. Schipper

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L. T C. Peltenburg

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12 March 2024

language of work or name

English

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National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14502243

12 March 2024

publication date

1 October 2003

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full work available at URL

22 September 2017

https://www.nature.com/articles/4401296.pdf

file format

Portable Document Format

online access status

open access

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14502243

http://www.nature.com/articles/4401296

12 March 2024

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https://api.crossref.org/works/10.1038/SJ.CDD.4401296

http://www.nature.com/articles/4401296.pdf

12 March 2024

file format

Portable Document Format

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https://api.crossref.org/works/10.1038/SJ.CDD.4401296

Cell Death & Differentiation

12 March 2024

published in

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22 September 2017

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22 September 2017

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22 September 2017

page(s)

1204-1212

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22 September 2017

cites work

Caspases: enemies within

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Death receptors: signaling and modulation

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Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome

21 January 2018

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A novel Apaf-1-independent putative caspase-2 activation complex

21 January 2018

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21 January 2018

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p53 mutations in human cutaneous melanoma correlate with sun exposure but are not always involved in melanomagenesis

21 January 2018

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Inactivation of the apoptosis effector Apaf-1 in malignant melanoma

21 January 2018

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Expression and targeting of the apoptosis inhibitor, survivin, in human melanoma

21 January 2018

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Structural basis for phosphoserine-proline recognition by group IV WW domains

21 January 2018

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ML-IAP, a novel inhibitor of apoptosis that is preferentially expressed in human melanomas

21 January 2018

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Livin, a novel inhibitor of apoptosis protein family member

21 January 2018

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A modified oestrogen receptor ligand-binding domain as an improved switch for the regulation of heterologous proteins

21 January 2018

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Defective Bax activation in Hodgkin B-cell lines confers resistance to staurosporine-induced apoptosis

21 January 2018

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A rapid, sensitive, and versatile assay for protein using Coomassie brilliant blue G250.

21 January 2018

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Biochemical Characteristics of Caspases-3, -6, -7, and -8

21 January 2018

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The three-dimensional structure of apopain/CPP32, a key mediator of apoptosis

21 January 2018

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Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis

21 January 2018

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Inhibition of human caspases by peptide-based and macromolecular inhibitors

21 January 2018

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Requirement for caspase-2 in stress-induced apoptosis before mitochondrial permeabilization

21 January 2018

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Synthetic low molecular weight inhibitors of serum kallikrein

21 January 2018

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A sequential two-step mechanism for the production of the mature p17:p12 form of caspase-3 in vitro

21 January 2018

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A Functional Role for Death Proteases in s-Myc- and c-Myc-Mediated Apoptosis

21 January 2018

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Inhibition of Ced-3/ICE-related proteases does not prevent cell death induced by oncogenes, DNA damage, or the Bcl-2 homologue Bak

21 January 2018

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Commitment to cell death measured by loss of clonogenicity is separable from the appearance of apoptotic markers

21 January 2018

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Blocking apoptosis prevents blindness in Drosophila retinal degeneration mutants.

21 January 2018

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Evidence for involvement of Bax and p53, but not caspases, in radiation-induced cell death of cultured postnatal hippocampal neurons

21 January 2018

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Characterization of the necrotic cleavage of poly(ADP-ribose) polymerase (PARP-1): implication of lysosomal proteases

21 January 2018

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Caspase-2 acts upstream of mitochondria to promote cytochrome c release during etoposide-induced apoptosis

21 January 2018

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Caspase-2 induces apoptosis by releasing proapoptotic proteins from mitochondria

21 January 2018

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Inhibitors of trypsin-like serine proteases prevent DNA damage-induced neuronal death by acting upstream of the mitochondrial checkpoint and of p53 induction.

21 January 2018

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Four deaths and a funeral: from caspases to alternative mechanisms.

21 January 2018

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Cathepsin B acts as a dominant execution protease in tumor cell apoptosis induced by tumor necrosis factor

21 January 2018

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Cathepsin B knockout mice are resistant to tumor necrosis factor-alpha-mediated hepatocyte apoptosis and liver injury: implications for therapeutic applications

21 January 2018

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Inhibition of endosomal insulin-like growth factor-I processing by cysteine proteinase inhibitors blocks receptor-mediated functions

21 January 2018

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Activation of the apoptotic protease CPP32 by cytotoxic T-cell-derived granzyme B.

21 January 2018

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Proapoptotic functions of cytotoxic lymphocyte granule constituents in vitro and in vivo.

21 January 2018

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Initiation of apoptosis by granzyme B requires direct cleavage of bid, but not direct granzyme B-mediated caspase activation.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401296

Granzyme B-mediated cytochrome c release is regulated by the Bcl-2 family members bid and Bax.

21 January 2018

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Calpain activation is upstream of caspases in radiation-induced apoptosis.

21 January 2018

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Cysteine proteinase inhibitors and ras gene products share the same biological activities including transforming activity toward NIH3T3 mouse fibroblasts and the differentiation-inducing activity toward PC12 rat pheochromocytoma cells

21 January 2018

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Identification of Omi/HtrA2 as a mitochondrial apoptotic serine protease that disrupts inhibitor of apoptosis protein-caspase interaction

21 January 2018

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HtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteins

21 January 2018

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The serine protease Omi/HtrA2 regulates apoptosis by binding XIAP through a reaper-like motif

21 January 2018

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The serine protease Omi/HtrA2 is released from mitochondria during apoptosis. Omi interacts with caspase-inhibitor XIAP and induces enhanced caspase activity

21 January 2018

1 reference

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Caspase-2 is not required for thymocyte or neuronal apoptosis even though cleavage of caspase-2 is dependent on both Apaf-1 and caspase-9

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401296

Apaf-1 oligomerizes into biologically active approximately 700-kDa and inactive approximately 1.4-MDa apoptosome complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401296

7 January 2021

Substrate specificities of caspase family proteases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401296

7 January 2021

Cleavage of Poly(ADP-ribose) Polymerase by Interleukin-1β Converting Enzyme and Its Homologs TX and Nedd-2

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401296

7 January 2021

The c-Myc-interacting adaptor protein Bin1 activates a caspase-independent cell death program

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401296

7 January 2021

Inhibitors of Trypsin‐Like Serine Proteases Inhibit Processing of the Caspase Nedd‐2 and Protect PC12 Cells and Sympathetic Neurons from Death Evoked by Withdrawal of Trophic Support

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401296

7 January 2021

5315

I Tamm

1998

1 reference

https://api.crossref.org/works/10.1038/SJ.CDD.4401296

12 March 2024

2110

JJ Tumilowicz

1970

1 reference

https://api.crossref.org/works/10.1038/SJ.CDD.4401296

c-myc down-regulates class I HLA expression in human melanomas

12 March 2024

1 reference

https://api.crossref.org/works/10.1038/SJ.CDD.4401296

12 March 2024

Identifiers

1 reference

Dimensions Publication ID

22 September 2017

1025625436

0 references

1 reference