Homology model of the dengue 2 virus NS3 protease: putative interactions with both substrate and NS2B cofactor. (Q40637828)

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8 December 2019

title

Homology model of the dengue 2 virus NS3 protease: putative interactions with both substrate and NS2B cofactor (English)

1 reference

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8 December 2019

1 reference

dengue NS2B-NS3 protease

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based on heuristic

inferred from abstract

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8 December 2019

Brinkworth RI

1 reference

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8 December 2019

Fairlie DP

series ordinal

1 reference

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8 December 2019

Leung D

series ordinal

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8 December 2019

language of work or name

English

0 references

publication date

1 May 1999

1 reference

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Journal of General Virology

8 December 2019

published in

1 reference

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8 December 2019

volume

80 ( Pt 5)

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8 December 2019

page(s)

1167-1177

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Kinetic and structural analyses of hepatitis C virus polyprotein processing

8 December 2019

cites work

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Hepatitis C virus-encoded nonstructural protein NS4A has versatile functions in viral protein processing

27 December 2022

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A simple method for displaying the hydropathic character of a protein

27 December 2022

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Mutagenesis of the yellow fever virus NS2B protein: effects on proteolytic processing, NS2B-NS3 complex formation, and viral replication

27 December 2022

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Complete nucleotide sequence of dengue type 3 virus genome RNA.

27 December 2022

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Flavivirus premembrane protein cleavage and spike heterodimer secretion require the function of the viral proteinase NS3.

27 December 2022

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The crystal structure of hepatitis C virus NS3 proteinase reveals a trypsin-like fold and a structural zinc binding site

27 December 2022

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27 December 2022

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Primary structure of the West Nile flavivirus genome region coding for all nonstructural proteins

27 December 2022

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Flavivirus enzyme-substrate interactions studied with chimeric proteinases: identification of an intragenic locus important for substrate recognition

27 December 2022

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Crystal structure of the hepatitis C virus NS3 protease domain complexed with a synthetic NS4A cofactor peptide

27 December 2022

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In vitro synthesis of West Nile virus proteins indicates that the amino-terminal segment of the NS3 protein contains the active centre of the protease which cleaves the viral polyprotein after multiple basic amino acids

27 December 2022

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Cotranslational Membrane Insertion of the Serine Proteinase Precursor NS2B-NS3(Pro) of Dengue Virus Type 2 Is Required for Efficient in Vitro Processing and Is Mediated through the Hydrophobic Regions of NS2B

27 December 2022

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Full-length cDNA sequence of dengue type 1 virus (Singapore strain S275/90)

27 December 2022

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Synthetic inhibitors of elastase

27 December 2022

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Gene mapping and positive identification of the non-structural proteins NS2A, NS2B, NS3, NS4B and NS5 of the flavivirus Kunjin and their cleavage sites

27 December 2022

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A zinc binding site in viral serine proteinases

27 December 2022

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Evidence that flavivirus NS1-NS2A cleavage is mediated by a membrane-bound host protease in the endoplasmic reticulum

27 December 2022

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Structure of Semliki Forest virus core protein

27 December 2022

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Detection of a trypsin-like serine protease domain in flaviviruses and pestviruses

27 December 2022

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Structural basis of substrate specificity in the serine proteases

27 December 2022

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Internal proteolysis of the NS3 protein specified by dengue virus 2.

27 December 2022

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Dengue 2 virus NS2B and NS3 form a stable complex that can cleave NS3 within the helicase domain

27 December 2022

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Transmembrane helices predicted at 95% accuracy

27 December 2022

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Complete nucleotide sequence of the Japanese encephalitis virus genome RNA.

27 December 2022

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The conformation of hepatitis C virus NS3 proteinase with and without NS4A: a structural basis for the activation of the enzyme by its cofactor.

27 December 2022

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Mutagenesis of the NS3 Protease of Dengue Virus Type 2

27 December 2022

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Complex of NS3 protease and NS4A peptide of BK strain hepatitis C virus: A 2.2 Å resolution structure in a hexagonal crystal form

27 December 2022

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Characterization of protease cleavage sites involved in the formation of the envelope glycoprotein and three non-structural proteins of dengue virus type 2, New Guinea C strain

27 December 2022

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Flavivirus genome organization, expression, and replication

27 December 2022

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Analyses of the terminal sequences of West Nile virus structural proteins and of the in vitro translation of these proteins allow the proposal of a complete scheme of the proteolytic cleavages involved in their synthesis

27 December 2022

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Structure of Sindbis virus core protein reveals a chymotrypsin-like serine proteinase and the organization of the virion

27 December 2022

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Partial N-terminal amino acid sequences of three nonstructural proteins of two flaviviruses

27 December 2022

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27 December 2022

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Enhancement of hepatitis C virus NS3 proteinase activity by association with NS4A-specific synthetic peptides: identification of sequence and critical residues of NS4A for the cofactor activity

27 December 2022

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Both nonstructural proteins NS2B and NS3 are required for the proteolytic processing of dengue virus nonstructural proteins

27 December 2022

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Nucleotide sequence of yellow fever virus: implications for flavivirus gene expression and evolution

27 December 2022

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27 December 2022

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N-terminal domains of putative helicases of flavi- and pestiviruses may be serine proteases

27 December 2022

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The nucleotide sequence of dengue type 4 virus: analysis of genes coding for nonstructural proteins

27 December 2022

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Virus-encoded proteinases of the Flaviviridae

27 December 2022

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Evidence that the N-terminal domain of nonstructural protein NS3 from yellow fever virus is a serine protease responsible for site-specific cleavages in the viral polyprotein

27 December 2022

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Ultrastructure of Kunjin virus-infected cells: colocalization of NS1 and NS3 with double-stranded RNA, and of NS2B with NS3, in virus-induced membrane structures

27 December 2022

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Cleavage at a novel site in the NS4A region by the yellow fever virus NS2B-3 proteinase is a prerequisite for processing at the downstream 4A/4B signalase site

27 December 2022

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In vitro processing of dengue virus type 2 nonstructural proteins NS2A, NS2B, and NS3

27 December 2022

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Proteolytic activation of tick-borne encephalitis virus by furin

27 December 2022

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Deletion analysis of dengue virus type 4 nonstructural protein NS2B: identification of a domain required for NS2B-NS3 protease activity

27 December 2022

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A central region in the hepatitis C virus NS4A protein allows formation of an active NS3-NS4A serine proteinase complex in vivo and in vitro

27 December 2022

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ChemInform Abstract: Towards Protein Surface Mimetics

27 December 2022

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Mimicking extended conformations of protease substrates

27 December 2022

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Characterization of the hepatitis C virus-encoded serine proteinase: determination of proteinase-dependent polyprotein cleavage sites

27 December 2022

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