FLT3 mutations in acute myeloid leukemia cell lines (Q40610364)

22 September 2017

title

FLT3 mutations in acute myeloid leukemia cell lines (English)

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22 September 2017

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acute myeloid leukemia

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Drexler HG

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22 September 2017

Quentmeier H

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22 September 2017

Reinhardt J

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22 September 2017

Zaborski M

series ordinal

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22 September 2017

publication date

1 January 2003

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22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

page(s)

120-124

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describes a project that uses

22 September 2017

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Internal tandem duplication of the FLT3 gene is preferentially seen in acute myeloid leukemia and myelodysplastic syndrome among various hematological malignancies. A study on a large series of patients and cell lines

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402740

Prevalence and prognostic significance of Flt3 internal tandem duplication in pediatric acute myeloid leukemia

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402740

Inhibition of FLT3-mediated transformation by use of a tyrosine kinase inhibitor

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402740

A FLT3 tyrosine kinase inhibitor is selectively cytotoxic to acute myeloid leukemia blasts harboring FLT3 internal tandem duplication mutations

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402740

Activating mutation of D835 within the activation loop of FLT3 in human hematologic malignancies

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402740

Identification of novel FLT-3 Asp835 mutations in adult acute myeloid leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402740

Essential role of signal transducer and activator of transcription (Stat)5a but not Stat5b for Flt3-dependent signaling

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402740

Constitutive activation of FLT3 stimulates multiple intracellular signal transducers and results in transformation.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402740

Extracellular signal-regulated kinase and p38 mitogen-activated protein kinase pathways cooperate in mediating cytokine-induced proliferation of a leukemic cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402740

Phosphatidylinositol-3' kinase is not required for mitogenesis or internalization of the Flt3/Flk2 receptor tyrosine kinase

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402740

Class III receptor tyrosine kinases: role in leukaemogenesis

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402740

Constitutive activation of FLT3 in acute myeloid leukaemia and its consequences for growth of 32D cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402740

Internal tandem duplication of FLT3 associated with leukocytosis in acute promyelocytic leukemia. Leukemia Study Group of the Ministry of Health and Welfare (Kohseisho)

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402740

7 January 2021

Biological characteristics and prognosis of adult acute myeloid leukemia with internal tandem duplications in the Flt3 gene

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402740

7 January 2021

Internal tandem duplication of the FLT3 gene is a novel modality of elongation mutation which causes constitutive activation of the product

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402740

7 January 2021

Tandem-duplicated Flt3 constitutively activates STAT5 and MAP kinase and introduces autonomous cell growth in IL-3-dependent cell lines

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402740

7 January 2021

Genomic structure of human FLT3: implications for mutational analysis

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402740

7 January 2021

Regulation of constitutive STAT5 phosphorylation in acute myeloid leukemia blasts.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402740

7 January 2021

Identifiers

DOI

10.1038/SJ.LEU.2402740

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Dimensions Publication ID

22 September 2017

1041582176

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