Inhibition of proteasomal function by curcumin induces apoptosis through mitochondrial pathway. (Q40602802)

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17 November 2019

title

Inhibition of proteasomal function by curcumin induces apoptosis through mitochondrial pathway (English)

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17 November 2019

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17 November 2019

Priyanka Dikshit

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17 November 2019

Anand Goswami

series ordinal

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17 November 2019

Nobuyuki Nukina

series ordinal

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17 November 2019

language of work or name

English

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publication date

30 December 2003

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Journal of Biological Chemistry

17 November 2019

published in

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17 November 2019

volume

279

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17 November 2019

issue

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17 November 2019

page(s)

11680-11685

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Pharmacology of Curcuma longa

17 November 2019

cites work

1 reference

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Inhibitory effects of topical application of low doses of curcumin on 12-O-tetradecanoylphorbol-13-acetate-induced tumor promotion and oxidized DNA bases in mouse epidermis.

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Inhibition of 7,12-dimethylbenz[a]anthracene (DMBA)-induced oral carcinogenesis in hamsters by tea and curcumin

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Curcumin-containing diet inhibits diethylnitrosamine-induced murine hepatocarcinogenesis.

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Curcumin downregulates cell survival mechanisms in human prostate cancer cell lines

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Curcumin (diferuloylmethane) induces apoptosis through activation of caspase-8, BID cleavage and cytochrome c release: its suppression by ectopic expression of Bcl-2 and Bcl-xl

21 January 2018

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Curcumin (diferuloylmethane) down-regulates the constitutive activation of nuclear factor-kappa B and IkappaBalpha kinase in human multiple myeloma cells, leading to suppression of proliferation and induction of apoptosis

21 January 2018

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Mechanisms of curcumin-induced apoptosis of Ehrlich's ascites carcinoma cells

21 January 2018

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Molecular mechanisms of curcumin-induced cytotoxicity: induction of apoptosis through generation of reactive oxygen species, down-regulation of Bcl-XL and IAP, the release of cytochrome c and inhibition of Akt.

21 January 2018

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Suppression of c-Jun/AP-1 activation by an inhibitor of tumor promotion in mouse fibroblast cells

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Inhibition of the c-Jun N-terminal kinase (JNK) signaling pathway by curcumin

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Curcumin induces the mitochondrial permeability transition pore mediated by membrane protein thiol oxidation

21 January 2018

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Curcumin induces a p53-dependent apoptosis in human basal cell carcinoma cells

21 January 2018

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Curcumin induces apoptosis in human melanoma cells through a Fas receptor/caspase-8 pathway independent of p53.

21 January 2018

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Activation of the cell death program by inhibition of proteasome function

21 January 2018

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Altered proteasomal function due to the expression of polyglutamine-expanded truncated N-terminal huntingtin induces apoptosis by caspase activation through mitochondrial cytochrome c release

21 January 2018

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Caspase activation during apoptotic cell death induced by expanded polyglutamine in N2a cells.

21 January 2018

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Cyclic AMP regulation of neutrophil apoptosis occurs via a novel protein kinase A-independent signaling pathway.

21 January 2018

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Pharmacophore model for novel inhibitors of ubiquitin isopeptidases that induce p53-independent cell death

21 January 2018

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Proteasome inhibition in oxidative stress neurotoxicity: implications for heat shock proteins.

21 January 2018

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Anti-tumour and antioxidant activity of natural curcuminoids

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Molecular sequelae of proteasome inhibition in human multiple myeloma cells

21 January 2018

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Biologic sequelae of nuclear factor-kappaB blockade in multiple myeloma: therapeutic applications

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Inhibition of cell survival signal protein kinase B/Akt by curcumin in human prostate cancer cells

21 January 2018

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Stimulation of the stress-induced expression of stress proteins by curcumin in cultured cells and in rat tissues in vivo

21 January 2018

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Curcumin-induced suppression of cell proliferation correlates with down-regulation of cyclin D1 expression and CDK4-mediated retinoblastoma protein phosphorylation

21 January 2018

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M310369200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14701837%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14701837%20AND%20SRC:MED&resulttype=core&format=json