P21(WAF1/CIP1) is dispensable for G1 arrest, but indispensable for apoptosis induced by sodium butyrate in MCF-7 breast cancer cells. (Q40601301)

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17 November 2019

title

P21(WAF1/CIP1) is dispensable for G1 arrest, but indispensable for apoptosis induced by sodium butyrate in MCF-7 breast cancer cells (English)

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17 November 2019

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17 November 2019

Valérie Chopin

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17 November 2019

Nathalie Jouy

series ordinal

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17 November 2019

Xuefen Le Bourhis

series ordinal

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17 November 2019

language of work or name

English

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publication date

1 January 2004

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17 November 2019

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17 November 2019

volume

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17 November 2019

issue

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17 November 2019

page(s)

21-29

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Existence of two populations of cyclin/proliferating cell nuclear antigen during the cell cycle: association with DNA replication sites

17 November 2019

cites work

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Inhibition of cyclin-dependent kinase 2 by p21 is necessary for retinoblastoma protein-mediated G1 arrest after gamma-irradiation

21 January 2018

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Downregulation of p21(waf/cip-1) mediates apoptosis of human hepatocellular carcinoma cells in response to interferon-gamma.

21 January 2018

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Mechanisms of c-myc-mediated transcriptional repression of growth arrest genes

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Role of p21 in apoptosis and senescence of human colon cancer cells treated with camptothecin

21 January 2018

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Butyrate activates the WAF1/Cip1 gene promoter through Sp1 sites in a p53-negative human colon cancer cell line

21 January 2018

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Histone deacetylase inhibitor selectively induces p21WAF1 expression and gene-associated histone acetylation

21 January 2018

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Sodium butyrate induces retinoblastoma protein dephosphorylation, p16 expression and growth arrest of colon cancer cells

21 January 2018

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Changes in cyclin/proliferating cell nuclear antigen distribution during DNA repair synthesis

21 January 2018

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Effects of sodium butyrate on expression of members of the IGF-binding protein superfamily in human mammary epithelial cells

21 January 2018

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Apoptosis inhibitory activity of cytoplasmic p21(Cip1/WAF1) in monocytic differentiation

21 January 2018

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7 January 2021

Requirement for p53 and p21 to sustain G2 arrest after DNA damage

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7 January 2021

Induction and superinduction of growth arrest and DNA damage gene 45 (GADD45) alpha and beta messenger RNAs by histone deacetylase inhibitors trichostatin A (TSA) and butyrate in SW620 human colon carcinoma cells

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7 January 2021

Sodium butyrate induces P53-independent, Fas-mediated apoptosis in MCF-7 human breast cancer cells

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7 January 2021

The C-terminal domain of p21 inhibits nucleotide excision repair In vitro and In vivo

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7 January 2021

New roles for p21 and p27 cell-cycle inhibitors: a function for each cell compartment?

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7 January 2021

Control of E2F activity by p21Waf1/Cip1

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7 January 2021

Genes modulated by histone acetylation as new effectors of butyrate activity

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7 January 2021

Effects of retinoic acid and sodium butyrate on gene expression, histone acetylation and inhibition of proliferation of melanoma cells

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7 January 2021

Different HATS of the ING1 gene family

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7 January 2021

Apoptosis sensitivity is not correlated with sensitivity to proliferation inhibition by the histone deacetylase inhibitors butyrate and TSA.

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7 January 2021

Induction of GADD45 and JNK/SAPK-dependent apoptosis following inducible expression of BRCA1.

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7 January 2021

Direct inhibition of the expression of cyclin D1 gene by sodium butyrate

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7 January 2021

p21 Waf1/Cip1 can protect human colon carcinoma cells against p53-dependent and p53-independent apoptosis induced by natural chemopreventive and therapeutic agents

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7 January 2021

Bcl-2 deregulation leads to inhibition of sodium butyrate-induced apoptosis in human colorectal carcinoma cells.

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7 January 2021

Inhibition of cell proliferation by the PCNA-binding region of p21 expressed as a GFP miniprotein

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7 January 2021

Regulation of MTK1/MEKK4 kinase activity by its N-terminal autoinhibitory domain and GADD45 binding

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7 January 2021

Cyclin D1-mediated inhibition of repair and replicative DNA synthesis in human fibroblasts.

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7 January 2021

Modulation of cell cycle-related protein expression by sodium butyrate in human non-small cell lung cancer cell lines

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7 January 2021

Regulation of NF-kappaB by cyclin-dependent kinases associated with the p300 coactivator

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7 January 2021

MyoD induces apoptosis in the absence of RB function through a p21(WAF1)-dependent re-localization of cyclin/cdk complexes to the nucleus

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7 January 2021

Cyclin kinase inhibitor p21 potentiates bile acid-induced apoptosis in hepatocytes that is dependent on p53.

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7 January 2021

Exogenous expression of p21(WAF1/CIP1) exerts cell growth inhibition and enhances sensitivity to cisplatin in hepatoma cells

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7 January 2021

Sustained nuclear localization of p21/WAF-1 upon growth arrest induced by contact inhibition

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7 January 2021

Growth inhibition by CDK-cyclin and PCNA binding domains of p21 occurs by distinct mechanisms and is regulated by ubiquitin-proteasome pathway

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7 January 2021

Histone deacetylase inhibition selectively alters the activity and expression of cell cycle proteins leading to specific chromatin acetylation and antiproliferative effects

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7 January 2021

Histone deacetylase inhibitors such as sodium butyrate and trichostatin A induce apoptosis through an increase of the bcl-2-related protein Bad.

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7 January 2021

Suppression of mammary carcinoma growth in vitro and in vivo by inducible expression of the Cdk inhibitor p21.

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7 January 2021

Cip1 inhibits DNA replication but not PCNA-dependent nucleotide excision-repair

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7 January 2021

A novel transcriptional repression domain mediates p21(WAF1/CIP1) induction of p300 transactivation

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7 January 2021

Butyrate as a model for "gene-regulating chemoprevention and chemotherapy.".

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7 January 2021

Procaspase 3/p21 complex formation to resist fas-mediated cell death is initiated as a result of the phosphorylation of p21 by protein kinase A

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7 January 2021

Sodium butyrate induces growth arrest and senescence-like phenotypes in gynecologic cancer cells

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7 January 2021

Differential activation of the IGF binding protein-3 promoter by butyrate in prostate cancer cells

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7 January 2021

Butyrate, a histone deacetylase inhibitor, activates the human IGF binding protein-3 promoter in breast cancer cells: molecular mechanism involves an Sp1/Sp3 multiprotein complex

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7 January 2021

Enhanced tumor killing by Apo2L/TRAIL and CPT-11 co-treatment is associated with p21 cleavage and differential regulation of Apo2L/TRAIL ligand and its receptors

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7 January 2021

Tumor suppressor p53 can participate in transcriptional induction of the GADD45 promoter in the absence of direct DNA binding

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7 January 2021

Caspase-mediated cleavage of p21Waf1/Cip1 converts cancer cells from growth arrest to undergoing apoptosis

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1207020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14712207%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

17 November 2019

1039535653

0 references

1 reference

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