Development of an efficient "substrate-trapping" mutant of Src homology phosphotyrosine phosphatase 2 and identification of the epidermal growth factor receptor, Gab1, and three other proteins as target substrates (Q40605597)

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scientific article published on 11 February 2003

Language	Label	Description	Also known as
English	Development of an efficient "substrate-trapping" mutant of Src homology phosphotyrosine phosphatase 2 and identification of the epidermal growth factor receptor, Gab1, and three other proteins as target substrates	scientific article published on 11 February 2003

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

Development of an efficient "substrate-trapping" mutant of Src homology phosphotyrosine phosphatase 2 and identification of the epidermal growth factor receptor, Gab1, and three other proteins as target substrates (English)

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

author name string

Yehenew M Agazie

1

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

Michael J Hayman

2

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

language of work or name

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publication date

11 February 2003

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Europe PubMed Central

PubMed publication ID

22 September 2017

number of pages

7

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based on heuristic

inferred from page(s)

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

22 September 2017

278

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Europe PubMed Central

PubMed publication ID

22 September 2017

16

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

13952-13958

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

Growth factor signaling by receptor tyrosine kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210670200

21 January 2018

Ligand-binding enhances the affinity of dimerization of the extracellular domain of the epidermal growth factor receptor.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210670200

21 January 2018

FRS2 proteins recruit intracellular signaling pathways by binding to diverse targets on fibroblast growth factor and nerve growth factor receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210670200

21 January 2018

Mammalian SH2-containing protein tyrosine phosphatases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210670200

21 January 2018

Protein tyrosine phosphatases take off.

1 reference

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21 January 2018

Phosphotyrosine phosphatases with SH2 domains: regulators of signal transduction

1 reference

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21 January 2018

Recruitment and activation of PTP1C in negative regulation of antigen receptor signaling by Fc gamma RIIB1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210670200

21 January 2018

Multiple requirements for SHPTP2 in epidermal growth factor-mediated cell cycle progression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210670200

21 January 2018

Protein tyrosine phosphatases in signal transduction.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210670200

21 January 2018

From form to function: signaling by protein tyrosine phosphatases.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210670200

21 January 2018

Protein phosphatases and the regulation of mitogen-activated protein kinase signalling.

1 reference

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21 January 2018

Modulation of insulin signaling by protein tyrosine phosphatases.

1 reference

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21 January 2018

Combinatorial control of the specificity of protein tyrosine phosphatases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210670200

21 January 2018

Abnormal mesoderm patterning in mouse embryos mutant for the SH2 tyrosine phosphatase Shp-2.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210670200

21 January 2018

The SH2 tyrosine phosphatase shp2 is required for mammalian limb development.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210670200

21 January 2018

Involvement of the protein tyrosine phosphatase SHP-1 in Ras-mediated activation of the mitogen-activated protein kinase pathway.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210670200

21 January 2018

SH2-containing phosphotyrosine phosphatase as a target of protein-tyrosine kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210670200

21 January 2018

Opposing actions of CSW and RasGAP modulate the strength of Torso RTK signaling in the Drosophila terminal pathway.

1 reference

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21 January 2018

The phosphotyrosine phosphatase SHP-2 participates in a multimeric signaling complex and regulates T cell receptor (TCR) coupling to the Ras/mitogen-activated protein kinase (MAPK) pathway in Jurkat T cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210670200

21 January 2018

Role of IRS-1-GRB-2 complexes in insulin signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210670200

21 January 2018

Binding of Shp2 tyrosine phosphatase to FRS2 is essential for fibroblast growth factor-induced PC12 cell differentiation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210670200

21 January 2018

Gab1 coupling to the HGF/Met receptor multifunctional docking site requires binding of Grb2 and correlates with the transforming potential.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210670200

21 January 2018

Grb2 mediates the EGF-dependent activation of guanine nucleotide exchange on Ras

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210670200

21 January 2018

Coupling of Gab1 to c-Met, Grb2, and Shp2 mediates biological responses

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210670200

21 January 2018

A novel membrane glycoprotein, SHPS-1, that binds the SH2-domain-containing protein tyrosine phosphatase SHP-2 in response to mitogens and cell adhesion

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210670200

21 January 2018

Roles of the complex formation of SHPS-1 with SHP-2 in insulin-stimulated mitogen-activated protein kinase activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210670200

21 January 2018

Development of "substrate-trapping" mutants to identify physiological substrates of protein tyrosine phosphatases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210670200

21 January 2018

Identification of p130(cas) as a substrate for the cytosolic protein tyrosine phosphatase PTP-PEST.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210670200

21 January 2018

Epidermal growth factor receptor and the adaptor protein p52Shc are specific substrates of T-cell protein tyrosine phosphatase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210670200

21 January 2018

A catalytic mechanism for the dual-specific phosphatases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210670200

21 January 2018

Dissecting the catalytic mechanism of protein-tyrosine phosphatases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210670200

21 January 2018

Structural basis for phosphotyrosine peptide recognition by protein tyrosine phosphatase 1B

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210670200

21 January 2018

The tyrosines in the bidentate motif of the env-sea oncoprotein are essential for cell transformation and are binding sites for Grb2 and the tyrosine phosphatase SHP-2.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210670200

21 January 2018

Concomitant activation of the PI3K-Akt and the Ras-ERK signaling pathways is essential for transformation by the V-SEA tyrosine kinase oncogene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210670200

21 January 2018

Identification of a putative Syp substrate, the PDGF beta receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210670200

21 January 2018

A common requirement for the catalytic activity and both SH2 domains of SHP-2 in mitogen-activated protein (MAP) kinase activation by the ErbB family of receptors. A specific role for SHP-2 in map, but not c-Jun amino-terminal kinase activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210670200

21 January 2018

Structural Determinants of SHP-2 Function and Specificity in Xenopus Mesoderm Induction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210670200

21 January 2018

Association of the T-cell protein tyrosine phosphatase with nuclear import factor p97

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210670200

21 January 2018

Identification of p130cas as an in vivo substrate of receptor protein-tyrosine phosphatase alpha

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210670200

21 January 2018

Crystal structure of the catalytic domain of protein-tyrosine phosphatase SHP-1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210670200

21 January 2018

Structural basis for substrate specificity of protein-tyrosine phosphatase SHP-1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210670200

21 January 2018

Design and characterization of an improved protein tyrosine phosphatase substrate-trapping mutant

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210670200

21 January 2018

Crystal structure of the tyrosine phosphatase SHP-2

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210670200

21 January 2018

Activated mutants of SHP-2 preferentially induce elongation of Xenopus animal caps

1 reference

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21 January 2018

Association of SH2 domain protein tyrosine phosphatases with the epidermal growth factor receptor in human tumor cells. Phosphatidic acid activates receptor dephosphorylation by PTP1C

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210670200

21 January 2018

Mice mutant for Egfr and Shp2 have defective cardiac semilunar valvulogenesis

1 reference

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21 January 2018

Characterization of a novel tyrosine phosphorylated 100-kDa protein that binds to SHP-2 and phosphatidylinositol 3'-kinase in myeloid cells

1 reference

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21 January 2018

Epidermal Growth Factor Stimulates the Tyrosine Phosphorylation of SHPS-1 and Association of SHPS-1 with SHP-2, a SH2 Domain-Containing Protein Tyrosine Phosphatase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210670200

21 January 2018

The SH2-containing protein-tyrosine phosphatase SH-PTP2 is required upstream of MAP kinase for early Xenopus development

1 reference

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21 January 2018

Requirement of SHP2 binding to Grb2-associated binder-1 for mitogen-activated protein kinase activation in response to lysophosphatidic acid and epidermal growth factor

1 reference

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21 January 2018

Identifiers

10.1074/JBC.M210670200

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

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