Role of p53 mutations, protein function and DNA damage for the radiosensitivity of human tumour cells (Q40592811)

21 September 2017

title

Role of p53 mutations, protein function and DNA damage for the radiosensitivity of human tumour cells (English)

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21 September 2017

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Böhnke A

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21 September 2017

Westphal F

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21 September 2017

Schmidt A

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21 September 2017

El-Awady RA

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21 September 2017

Dahm-Daphi J

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21 September 2017

publication date

1 January 2004

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International Journal of Radiation Biology

21 September 2017

published in

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21 September 2017

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21 September 2017

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21 September 2017

page(s)

53-63

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DNA substrate dependence of p53-mediated regulation of double-strand break repair

21 September 2017

cites work

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TP53 mutation is related to poor prognosis after radiotherapy, but not surgery, in squamous cell carcinoma of the head and neck

21 January 2018

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p53 binds single-stranded DNA ends and catalyzes DNA renaturation and strand transfer.

21 January 2018

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Mechanisms of p53-mediated apoptosis

21 January 2018

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Requirement for p53 and p21 to sustain G2 arrest after DNA damage

21 January 2018

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Oncogenes in radioresistant, noncancerous skin fibroblasts from a cancer-prone family.

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Thymocyte apoptosis induced by p53-dependent and independent pathways.

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Adenoviral-mediated p53 transgene expression sensitizes both wild-type and null p53 prostate cancer cells in vitro to radiation

21 January 2018

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p53: biology and role for cellular radiosensitivity

21 January 2018

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Repair of DNA double-strand breaks and radiosensitivity to killing in an isogenic group of p53 mutant cell lines

21 January 2018

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Homologous and nonhomologous recombination resulting in deletion: effects of p53 status, microhomology, and repetitive DNA length and orientation

21 January 2018

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The complexity of p53 modulation: emerging patterns from divergent signals

21 January 2018

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p53 mutation is a poor prognostic indicator for survival in patients with hepatocellular carcinoma undergoing surgical tumour ablation

21 January 2018

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p53 mutation and locoregional treatment failure in head and neck squamous cell carcinoma

21 January 2018

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Different impact of p53 and p21 on the radiation response of mouse tissues

21 January 2018

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Wild-type p53 is a cell cycle checkpoint determinant following irradiation

21 January 2018

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Adenovirus-p53 gene therapy in human nasopharyngeal carcinoma xenografts.

21 January 2018

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p53 mutations increase resistance to ionizing radiation

21 January 2018

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Twenty years of p53 research: structural and functional aspects of the p53 protein

21 January 2018

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p53 mutation, but not p53 overexpression, correlates with survival in head and neck squamous cell carcinoma

21 January 2018

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DNA strand breaks: the DNA template alterations that trigger p53-dependent DNA damage response pathways

21 January 2018

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Transfection of rat embryo cells with mutant p53 increases the intrinsic radiation resistance.

21 January 2018

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The G(2) checkpoint is maintained by redundant pathways

21 January 2018

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p53 mediated sensitization of squamous cell carcinoma of the head and neck to radiotherapy

21 January 2018

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p53 is a chromatin accessibility factor for nucleotide excision repair of DNA damage

21 January 2018

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Mutant p53 proteins stimulate spontaneous and radiation-induced intrachromosomal homologous recombination independently of the alteration of the transactivation activity and of the G1 checkpoint.

21 January 2018

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The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53

21 January 2018

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p53 inhibits entry into mitosis when DNA synthesis is blocked

21 January 2018

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Regulation of the G2/M transition by p53.

21 January 2018

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Combined RAF1 protein expression and p53 mutational status provides a strong predictor of cellular radiosensitivity

21 January 2018

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P63 and P73: P53 mimics, menaces and more

21 January 2018

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Radiation induced G1-block and p53 status in six human cell lines

21 January 2018

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Transfection of a vector expressing wild-type p53 into cells of two human glioma cell lines enhances radiation toxicity.

21 January 2018

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p53 Protein exhibits 3'-to-5' exonuclease activity

21 January 2018

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Prolonged cell cycle delay in radioresistant human cell lines transfected with activated ras oncogene and/or simian virus 40 T-antigen.

21 January 2018

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10.1080/09553000310001642902

21 January 2018

Identifiers

DOI

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21 September 2017

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