A trade-off in replication in mosquito versus mammalian systems conferred by a point mutation in the NS4B protein of dengue virus type 4. (Q40553373)

21 September 2017

title

A trade-off in replication in mosquito versus mammalian systems conferred by a point mutation in the NS4B protein of dengue virus type 4. (English)

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21 September 2017

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Stephen S Whitehead

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21 September 2017

Kathryn A Hanley

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21 September 2017

Joseph E Blaney

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21 September 2017

Brian R Murphy

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21 September 2017

Christopher T Hanson

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21 September 2017

Luella R Manlucu

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21 September 2017

Lara E Gilmore

series ordinal

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21 September 2017

language of work or name

English

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publication date

1 July 2003

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21 September 2017

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inferred from page(s)

published in

Virology

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21 September 2017

volume

312

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21 September 2017

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21 September 2017

page(s)

222-232

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Live attenuated tetravalent dengue vaccine

21 September 2017

cites work

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Chemical mutagenesis of dengue virus type 4 yields mutant viruses which are temperature sensitive in vero cells or human liver cells and attenuated in mice

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Genetic basis of attenuation of dengue virus type 4 small plaque mutants with restricted replication in suckling mice and in SCID mice transplanted with human liver cells

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Attenuation markers of a candidate dengue type 2 vaccine virus, strain 16681 (PDK-53), are defined by mutations in the 5' noncoding region and nonstructural proteins 1 and 3

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Paired charge-to-alanine mutagenesis of dengue virus type 4 NS5 generates mutants with temperature-sensitive, host range, and mouse attenuation phenotypes

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Identifiers

DOI

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21 September 2017

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