MCL1 is phosphorylated in the PEST region and stabilized upon ERK activation in viable cells, and at additional sites with cytotoxic okadaic acid or taxol (Q40537978)

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scientific article published on July 2004

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English	MCL1 is phosphorylated in the PEST region and stabilized upon ERK activation in viable cells, and at additional sites with cytotoxic okadaic acid or taxol	scientific article published on July 2004

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

MCL1 is phosphorylated in the PEST region and stabilized upon ERK activation in viable cells, and at additional sites with cytotoxic okadaic acid or taxol (English)

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

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phosphorylation

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author name string

Aaron M Domina

1

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Europe PubMed Central

PubMed publication ID

21 September 2017

Julie A Vrana

2

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

Mark A Gregory

3

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

Stephen R Hann

4

1 reference

Europe PubMed Central

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21 September 2017

Ruth W Craig

5

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

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publication date

1 July 2004

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Europe PubMed Central

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21 September 2017

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

23

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Europe PubMed Central

PubMed publication ID

21 September 2017

31

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Europe PubMed Central

PubMed publication ID

21 September 2017

5301-5315

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Europe PubMed Central

PubMed publication ID

21 September 2017

Exon skipping in Mcl-1 results in a bcl-2 homology domain 3 only gene product that promotes cell death

1 reference

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Mono- and multisite phosphorylation enhances Bcl2's antiapoptotic function and inhibition of cell cycle entry functions

1 reference

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Survival function of ERK1/2 as IL-3-activated, staurosporine-resistant Bcl2 kinases

1 reference

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Novel role for JNK as a stress-activated Bcl2 kinase

1 reference

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Dephosphorylation targets Bcl-2 for ubiquitin-dependent degradation: a link between the apoptosome and the proteasome pathway.

1 reference

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Myeloid cell leukemia 1 is phosphorylated through two distinct pathways, one associated with extracellular signal-regulated kinase activation and the other with G2/M accumulation or protein phosphatase 1/2A inhibition

1 reference

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21 January 2018

Inhibition of cell proliferation and cell cycle progression by specific inhibition of basal JNK activity: evidence that mitotic Bcl-2 phosphorylation is JNK-independent

1 reference

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Phosphorylation by Glycogen Synthase Kinase-3 Controls c-Myc Proteolysis and Subnuclear Localization

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p70S6 kinase signals cell survival as well as growth, inactivating the pro-apoptotic molecule BAD

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Phosphorylation and inactivation of myeloid cell leukemia 1 by JNK in response to oxidative stress

1 reference

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Bcl-2 phosphorylation required for anti-apoptosis function

1 reference

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21 January 2018

MCL1, a gene expressed in programmed myeloid cell differentiation, has sequence similarity to BCL2

1 reference

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Generation of destabilized green fluorescent protein as a transcription reporter

1 reference

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Bcl-2 undergoes phosphorylation by c-Jun N-terminal kinase/stress-activated protein kinases in the presence of the constitutively active GTP-binding protein Rac1.

1 reference

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BCL-2 and MCL-1 expression in Chinese hamster ovary cells inhibits intracellular acidification and apoptosis induced by staurosporine

1 reference

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Regulation of bad phosphorylation and association with Bcl-x(L) by the MAPK/Erk kinase

1 reference

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Deletion of the loop region of Bcl-2 completely blocks paclitaxel-induced apoptosis

1 reference

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Chemically induced premature mitosis: differential response in rodent and human cells and the relationship to cyclin B synthesis and p34cdc2/cyclin B complex formation

1 reference

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Analysis of the structure, transcripts, and protein products of bcl-2, the gene involved in human follicular lymphoma

1 reference

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21 January 2018

Phosphorylation of Bcl-2 in G2/M phase-arrested cells following photodynamic therapy with hypericin involves a CDK1-mediated signal and delays the onset of apoptosis.

1 reference

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21 January 2018

The intracellular distribution and pattern of expression of Mcl-1 overlap with, but are not identical to, those of Bcl-2

1 reference

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21 January 2018

In vivo localisation and stability of human Mcl-1 using green fluorescent protein (GFP) fusion proteins

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Unwinding the loop of Bcl-2 phosphorylation

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Posttranslational modification of Bcl-2 facilitates its proteasome-dependent degradation: molecular characterization of the involved signaling pathway.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207692

7 January 2021

based on heuristic

inferred from DOI database lookup

Cloning and characterization of a novel nuclear Bcl-2 family protein, zfMcl-1a, in zebrafish embryo.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Turnover of cyclin E by the ubiquitin-proteasome pathway is regulated by cdk2 binding and cyclin phosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207692

7 January 2021

based on heuristic

inferred from DOI database lookup

MCL1 provides a window on the role of the BCL2 family in cell proliferation, differentiation and tumorigenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207692

7 January 2021

based on heuristic

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DNA damage response and MCL-1 destruction initiate apoptosis in adenovirus-infected cells

1 reference

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7 January 2021

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Vinblastine-induced phosphorylation of Bcl-2 and Bcl-XL is mediated by JNK and occurs in parallel with inactivation of the Raf-1/MEK/ERK cascade

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Phosphorylation of Bcl-2 protein by CDC2 kinase during G2/M phases and its role in cell cycle regulation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207692

7 January 2021

based on heuristic

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c-Myc proteolysis by the ubiquitin-proteasome pathway: stabilization of c-Myc in Burkitt's lymphoma cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207692

7 January 2021

based on heuristic

inferred from DOI database lookup

Phosphorylation-dependent ubiquitination of cyclin E by the SCFFbw7 ubiquitin ligase

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Phosphorylation of Bim-EL by Erk1/2 on serine 69 promotes its degradation via the proteasome pathway and regulates its proapoptotic function.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207692

7 January 2021

based on heuristic

inferred from DOI database lookup

Hierarchical phosphorylation at N-terminal transformation-sensitive sites in c-Myc protein is regulated by mitogens and in mitosis

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Rum1, an inhibitor of cyclin-dependent kinase in fission yeast, is negatively regulated by mitogen-activated protein kinase-mediated phosphorylation at Ser and Thr residues

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Reduced ubiquitin-dependent degradation of c-Jun after phosphorylation by MAP kinases

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Elimination of Mcl-1 is required for the initiation of apoptosis following ultraviolet irradiation

1 reference

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7 January 2021

based on heuristic

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Development and maintenance of B and T lymphocytes requires antiapoptotic MCL-1.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Mitotic phosphorylation of Bcl-2 during normal cell cycle progression and Taxol-induced growth arrest

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Ras enhances Myc protein stability.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Involvement of microtubules in the regulation of Bcl2 phosphorylation and apoptosis through cyclic AMP-dependent protein kinase

1 reference

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based on heuristic

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p53 mediates bcl-2 phosphorylation and apoptosis via activation of the Cdc42/JNK1 pathway

1 reference

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7 January 2021

based on heuristic

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Expression of the antiapoptotic MCL1 gene product is regulated by a mitogen activated protein kinase-mediated pathway triggered through microtubule disruption and protein kinase C.

1 reference

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7 January 2021

based on heuristic

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Regulation of MCL1 through a serum response factor/Elk-1-mediated mechanism links expression of a viability-promoting member of the BCL2 family to the induction of hematopoietic cell differentiation

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Ca2+-induced apoptosis through calcineurin dephosphorylation of BAD

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

BCL-2 is phosphorylated and inactivated by an ASK1/Jun N-terminal protein kinase pathway normally activated at G(2)/M.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207692

7 January 2021

based on heuristic

inferred from DOI database lookup

MCL-1, a member of the BLC-2 family, is induced rapidly in response to signals for cell differentiation or death, but not to signals for cell proliferation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207692

7 January 2021

based on heuristic

inferred from DOI database lookup

MCL1 transgenic mice exhibit a high incidence of B-cell lymphoma manifested as a spectrum of histologic subtypes.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207692

7 January 2021

based on heuristic

inferred from DOI database lookup

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10.1038/SJ.ONC.1207692

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Europe PubMed Central

PubMed publication ID

21 September 2017

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1 reference

https://api.fatcat.wiki/v0/release/xu5ta4zcnnec3mjqpwh6ks67yu

24 November 2022

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PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

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