Complete reversal of multidrug resistance by stable expression of small interfering RNAs targeting MDR1. (Q40507972)

21 September 2017

title

Complete reversal of multidrug resistance by stable expression of small interfering RNAs targeting MDR1. (English)

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21 September 2017

main subject

multiple drug resistance

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Yagüe E

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21 September 2017

Higgins CF

series ordinal

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21 September 2017

Raguz S

series ordinal

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21 September 2017

publication date

1 July 2004

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21 September 2017

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21 September 2017

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21 September 2017

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21 September 2017

page(s)

1170-1174

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Multidrug resistance in cancer: role of ATP-dependent transporters

21 September 2017

cites work

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The orphan nuclear receptor SXR coordinately regulates drug metabolism and efflux

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Modulation of the typical multidrug resistance phenotype by targeting the MED-1 region of human MDR1 promoter

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Retrovirus-mediated transfer of anti-MDR1 ribozymes fully restores chemosensitivity of P-glycoprotein-expressing human lymphoma cells

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A system for stable expression of short interfering RNAs in mammalian cells

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Efficient lentiviral vectors for short hairpin RNA delivery into human cells

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Modulation of the classical multidrug resistance (MDR) phenotype by RNA interference (RNAi).

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Multiple mechanisms confer different drug-resistant phenotypes in pancreatic carcinoma cells

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P-glycoprotein stability is affected by serum deprivation and high cell density in multidrug-resistant cells

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P-glycoprotein (MDR1) expression in leukemic cells is regulated at two distinct steps, mRNA stabilization and translational initiation

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RNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cells

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Genomewide view of gene silencing by small interfering RNAs

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Lentivirus-delivered stable gene silencing by RNAi in primary cells

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MDR1 gene overexpression confers resistance to imatinib mesylate in leukemia cell line models

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Comparative gene expression profile of chronic myeloid leukemia cells innately resistant to imatinib mesylate

21 January 2018

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MULTIDRUG RESISTANCE IN LEUKAEMIA

21 January 2018

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Distinct Initiation and Maintenance Mechanisms Cooperate to Induce G1 Cell Cycle Arrest in Response to DNA Damage

21 January 2018

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Overexpression of cytochrome P450 CYP2J2 protects against hypoxia-reoxygenation injury in cultured bovine aortic endothelial cells

21 January 2018

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inferred from DOI database lookup

7 January 2021

based on heuristic

An epi-allelic series of p53 hypomorphs created by stable RNAi produces distinct tumor phenotypes in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302269

inferred from DOI database lookup

7 January 2021

based on heuristic

Chronic myeloid leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302269

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/SJ.GT.3302269

1 reference

Dimensions Publication ID

21 September 2017

1003044710

0 references

1 reference