K+ channel types targeted by synthetic OSK1, a toxin from Orthochirus scrobiculosus scorpion venom. (Q40482896)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15588251%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

title

K+ channel types targeted by synthetic OSK1, a toxin from Orthochirus scrobiculosus scorpion venom (English)

1 reference

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Orthochirus scrobiculosus

6 January 2020

main subject

venom

0 references

object named as

Orthochirus scrobiculosus

1 reference

1 reference

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6 January 2020

1 reference

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6 January 2020

Stéphanie Mouhat

1 reference

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6 January 2020

Violeta Visan

1 reference

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6 January 2020

S Ananthakrishnan

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6 January 2020

Heike Wulff

1 reference

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6 January 2020

Nicolas Andreotti

1 reference

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6 January 2020

Stephan Grissmer

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6 January 2020

Hervé Darbon

1 reference

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6 January 2020

language of work or name

English

0 references

publication date

1 January 2005

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6 January 2020

number of pages

1 reference

inferred from page(s)

published in

Biochemical Journal

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6 January 2020

volume

385

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6 January 2020

issue

Pt 1

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6 January 2020

page(s)

95-104

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Current views on scorpion toxins specific for K+-channels

6 January 2020

cites work

1 reference

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Computational simulations of interactions of scorpion toxins with the voltage-gated potassium ion channel

22 September 2017

1 reference

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K+ channels as targets for specific immunomodulation

22 September 2017

1 reference

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Ion channels and lymphocyte activation

22 September 2017

1 reference

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Diversity of folds in animal toxins acting on ion channels.

22 September 2017

1 reference

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Cobatoxin 1 from Centruroides noxius scorpion venom: chemical synthesis, three-dimensional structure in solution, pharmacology and docking on K+ channels

22 September 2017

1 reference

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The voltage-gated Kv1.3 K(+) channel in effector memory T cells as new target for MS

22 September 2017

1 reference

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Novel interactions between K+ channels and scorpion toxins

22 September 2017

1 reference

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Characterisation of the human voltage-gated potassium channel gene, KCNA7, a candidate gene for inherited cardiac disorders, and its exclusion as cause of progressive familial heart block I (PFHBI).

22 September 2017

1 reference

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Selective blockade of T lymphocyte K(+) channels ameliorates experimental autoimmune encephalomyelitis, a model for multiple sclerosis

22 September 2017

1 reference

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A unified nomenclature for short-chain peptides isolated from scorpion venoms: alpha-KTx molecular subfamilies

22 September 2017

1 reference

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ShK-Dap22, a potent Kv1.3-specific immunosuppressive polypeptide

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134677

Blockade of the voltage-gated potassium channel Kv1.3 inhibits immune responses in vivo

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134677

Three-dimensional structure of toxin OSK1 from Orthochirus scrobiculosus scorpion venom

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134677

Purification and characterization of three inhibitors of voltage-dependent K+ channels from Leiurus quinquestriatus var. hebraeus venom

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134677

Topology of the pore-region of a K+ channel revealed by the NMR-derived structures of scorpion toxins

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134677

Pharmacological characterization of five cloned voltage-gated K+ channels, types Kv1.1, 1.2, 1.3, 1.5, and 3.1, stably expressed in mammalian cell lines

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134677

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134677

Refined Structure of Charybdotoxin: Common Motifs in Scorpion Toxins and Insect Defensins

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134677

Selective blocking of voltage-gated K+ channels improves experimental autoimmune encephalomyelitis and inhibits T cell activation

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134677

Structure-guided transformation of charybdotoxin yields an analog that selectively targets Ca(2+)-activated over voltage-gated K(+) channels.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134677

The 'functional' dyad of scorpion toxin Pi1 is not itself a prerequisite for toxin binding to the voltage-gated Kv1.2 potassium channels.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134677

Two novel toxins from the Amazonian scorpion Tityus cambridgei that block Kv1.3 and Shaker B K(+)-channels with distinctly different affinities.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134677

A four-disulphide-bridged toxin, with high affinity towards voltage-gated K+ channels, isolated from Heterometrus spinnifer (Scorpionidae) venom

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134677

Purification, Characterization, and Synthesis of Three Novel Toxins from the Chinese ScorpionButhus martensi, Which Act on K+Channels

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134677

Mapping of maurotoxin binding sites on hKv1.2, hKv1.3, and hIKCa1 channels

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134677

Block of maurotoxin and charybdotoxin on human intermediate-conductance calcium-activated potassium channels (hIKCa1).

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134677

Synthesis and characterization of Pi4, a scorpion toxin from Pandinus imperator that acts on K+ channels.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134677

Maurotoxin: a potent inhibitor of intermediate conductance Ca2+-activated potassium channels.

20 August 2018

1 reference

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Maurotoxin versus Pi1/HsTx1 scorpion toxins. Toward new insights in the understanding of their distinct disulfide bridge patterns.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134677

Chemical synthesis and characterization of Pi1, a scorpion toxin from Pandinus imperator active on K+ channels

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134677

P05, a new leiurotoxin I-like scorpion toxin: synthesis and structure-activity relationships of the alpha-amidated analog, a ligand of Ca(2+)-activated K+ channels with increased affinity

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134677

Evidence for an internal phenylalkylamine action on the voltage-gated potassium channel Kv1.3.

20 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15588251

12 December 2020

inferred from PubMed ID database lookup

Synthesis and characterization of kaliotoxin. Is the 26-32 sequence essential for potassium channel recognition?

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15588251

12 December 2020

inferred from PubMed ID database lookup

Solid phase synthesis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15588251

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1042/BJ20041379

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15588251%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15588251%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

PubMed publication ID

15588251

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15588251%20AND%20SRC:MED&resulttype=core&format=json