Global effects of BCR/ABL and TEL/PDGFRbeta expression on the proteome and phosphoproteome: identification of the Rho pathway as a target of BCR/ABL. (Q40486959)

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English	Global effects of BCR/ABL and TEL/PDGFRbeta expression on the proteome and phosphoproteome: identification of the Rho pathway as a target of BCR/ABL.	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

21 September 2017

Global effects of BCR/ABL and TEL/PDGFRbeta expression on the proteome and phosphoproteome: identification of the Rho pathway as a target of BCR/ABL. (English)

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

4

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

object named as

Richard D Unwin

1

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Anthony D Whetton

object named as

Anthony D Whetton

6

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author name string

David W Sternberg

2

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Europe PubMed Central

PubMed publication ID

21 September 2017

Yuning Lu

3

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Europe PubMed Central

PubMed publication ID

21 September 2017

D Gary Gilliland

5

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Europe PubMed Central

PubMed publication ID

21 September 2017

language of work or name

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publication date

29 November 2004

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Europe PubMed Central

PubMed publication ID

21 September 2017

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

21 September 2017

280

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Europe PubMed Central

PubMed publication ID

21 September 2017

8

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

6316-6326

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Europe PubMed Central

PubMed publication ID

21 September 2017

Chronic myelogenous leukemia: a review

1 reference

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21 January 2018

The chronic myelogenous leukemia-specific P210 protein is the product of the bcr/abl hybrid gene

1 reference

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Coupling between p210bcr-abl and Shc and Grb2 adaptor proteins in hematopoietic cells permits growth factor receptor-independent link to ras activation pathway

1 reference

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21 January 2018

Tyrosyl phosphorylation and DNA binding activity of signal transducers and activators of transcription (STAT) proteins in hematopoietic cell lines transformed by Bcr/Abl

1 reference

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21 January 2018

Inhibition of protein kinase C delta has negative effect on anchorage-independent growth of BCR-ABL-transformed Rat1 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410598200

21 January 2018

TEL/platelet-derived growth factor receptor beta activates phosphatidylinositol 3 (PI3) kinase and requires PI3 kinase to regulate the cell cycle

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410598200

21 January 2018

TEL/PDGFbetaR fusion protein activates STAT1 and STAT5: a common mechanism for transformation by tyrosine kinase fusion proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410598200

21 January 2018

The TEL/platelet-derived growth factor beta receptor (PDGF beta R) fusion in chronic myelomonocytic leukemia is a transforming protein that self-associates and activates PDGF beta R kinase-dependent signaling pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410598200

21 January 2018

Inhibition of the ABL kinase activity blocks the proliferation of BCR/ABL+ leukemic cells and induces apoptosis.

1 reference

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21 January 2018

Imatinib mesylate therapy in newly diagnosed patients with Philadelphia chromosome-positive chronic myelogenous leukemia: high incidence of early complete and major cytogenetic responses

1 reference

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Response to imatinib mesylate in patients with chronic myeloproliferative diseases with rearrangements of the platelet-derived growth factor receptor beta

1 reference

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Resistance of Philadelphia-chromosome positive leukemia towards the kinase inhibitor imatinib (STI571, Glivec): a targeted oncoprotein strikes back

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21 January 2018

Chronic myelogenous leukemia molecular signature.

1 reference

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21 January 2018

Dietary glycine inhibits angiogenesis during wound healing and tumor growth

1 reference

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Identification of genes differentially regulated by the P210 BCR/ABL1 fusion oncogene using cDNA microarrays

1 reference

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21 January 2018

Oncogenic Abl and Src tyrosine kinases elicit the ubiquitin-dependent degradation of target proteins through a Ras-independent pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410598200

21 January 2018

Transforming growth factor-beta 1 induces apoptosis independently of p53 and selectively reduces expression of Bcl-2 in multipotent hematopoietic cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410598200

21 January 2018

BCR/ABL activates mdm2 mRNA translation via the La antigen

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410598200

21 January 2018

Post-transcriptional mechanisms in BCR/ABL leukemogenesis: role of shuttling RNA-binding proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410598200

21 January 2018

Transformation of an interleukin 3-dependent hematopoietic cell line by the chronic myelogenous leukemia-specific P210bcr/abl protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410598200

21 January 2018

p210 Bcr-Abl expression in a primitive multipotent haematopoietic cell line models the development of chronic myeloid leukaemia.

1 reference

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21 January 2018

Proteomic changes in renal cancer and co-ordinate demonstration of both the glycolytic and mitochondrial aspects of the Warburg effect

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410598200

21 January 2018

Mass Spectrometric Sequencing of Proteins from Silver-Stained Polyacrylamide Gels

1 reference

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21 January 2018

Gelsolin is a downstream effector of rac for fibroblast motility

1 reference

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21 January 2018

Functions of gelsolin: motility, signaling, apoptosis, cancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410598200

21 January 2018

The interaction of Arp2/3 complex with actin: nucleation, high affinity pointed end capping, and formation of branching networks of filaments

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410598200

21 January 2018

Caspase-3-Generated Fragment of Gelsolin: Effector of Morphological Change in Apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410598200

21 January 2018

ARG tyrosine kinase activity is inhibited by STI571.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410598200

21 January 2018

Differential interaction and activation of Rho family GTPases by p210bcr-abl and p190bcr-abl

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410598200

21 January 2018

Inhibition of Grb2 and Crkl proteins results in growth inhibition of Philadelphia chromosome positive leukemic cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410598200

21 January 2018

Lineage-related polypeptide markers in acute lymphoblastic leukemia detected by two-dimensional gel electrophoresis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410598200

21 January 2018

Association of the protein kinases c-Bcr and Bcr-Abl with proteins of the 14-3-3 family

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410598200

21 January 2018

14-3-3Gamma interacts with and is phosphorylated by multiple protein kinase C isoforms in PDGF-stimulated human vascular smooth muscle cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410598200

21 January 2018

Suppression of Raf-1 kinase activity and MAP kinase signalling by RKIP

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410598200

21 January 2018

14-3-3 Interacts directly with and negatively regulates pro-apoptotic Bax

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410598200

21 January 2018

14-3-3 proteins block apoptosis and differentially regulate MAPK cascades

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410598200

21 January 2018

Mechanisms underlying abnormal trafficking of malignant progenitors in chronic myelogenous leukemia. Decreased adhesion to stroma and fibronectin but increased adhesion to the basement membrane components laminin and collagen type IV

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410598200

21 January 2018

Cellular motility driven by assembly and disassembly of actin filaments

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410598200

21 January 2018

Expression of scinderin in megakaryoblastic leukemia cells induces differentiation, maturation, and apoptosis with release of plateletlike particles and inhibits proliferation and tumorigenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410598200

21 January 2018

The Arp2/3 complex nucleates actin filament branches from the sides of pre-existing filaments

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410598200

21 January 2018

Expression of FLRG, a novel activin A ligand, is regulated by TGF-beta and during hematopoiesis [corrected].

1 reference

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Regulation of follistatin-related gene (FLRG) expression by protein kinase C and prostaglandin E(2) in cultured granulosa-luteal cells

1 reference

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Transcription activation of FLRG and follistatin by activin A, through Smad proteins, participates in a negative feedback loop to modulate activin A function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410598200

21 January 2018

Global quantitative phosphoprotein analysis using Multiplexed Proteomics technology

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410598200

21 January 2018

CrkL functions as a nuclear adaptor and transcriptional activator in Bcr-Abl-expressing cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410598200

21 January 2018

Role of the adapter protein CRKL in signal transduction of normal hematopoietic and BCR/ABL-transformed cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410598200

21 January 2018

BCR-ABL point mutants isolated from patients with imatinib mesylate-resistant chronic myeloid leukemia remain sensitive to inhibitors of the BCR-ABL chaperone heat shock protein 90.

1 reference

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21 January 2018

Hsp90 phosphorylation is linked to its chaperoning function. Assembly of the reovirus cell attachment protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410598200

21 January 2018

A novel phosphorylation-dependent RNase activity of GAP-SH3 binding protein: a potential link between signal transduction and RNA stability

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410598200

21 January 2018

Nedd5, a mammalian septin, is a novel cytoskeletal component interacting with actin-based structures

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410598200

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Both stimulatory and inhibitory exchange proteins, smg GDS and rho GDI, are active on multiple small GTP-binding proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410598200

21 January 2018

Rho GTPases and the Actin Cytoskeleton

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410598200

21 January 2018

BCR/ABL induces multiple abnormalities of cytoskeletal function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410598200

21 January 2018

Comparative proteomics of primitive hematopoietic cell populations reveals differences in expression of proteins regulating motility

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410598200

21 January 2018

Identifiers

10.1074/JBC.M410598200

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

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