Lithium activates the Wnt and phosphatidylinositol 3-kinase Akt signaling pathways to promote cell survival in the absence of soluble survival factors (Q40486178)

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English	Lithium activates the Wnt and phosphatidylinositol 3-kinase Akt signaling pathways to promote cell survival in the absence of soluble survival factors	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

20 September 2017

Lithium activates the Wnt and phosphatidylinositol 3-kinase Akt signaling pathways to promote cell survival in the absence of soluble survival factors (English)

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Europe PubMed Central

PubMed publication ID

20 September 2017

author name string

Diviya Sinha

1

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Europe PubMed Central

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20 September 2017

Zhiyong Wang

2

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Europe PubMed Central

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20 September 2017

Kathleen L Ruchalski

3

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Europe PubMed Central

PubMed publication ID

20 September 2017

Jerrold S Levine

4

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Europe PubMed Central

PubMed publication ID

20 September 2017

Selvi Krishnan

5

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Europe PubMed Central

PubMed publication ID

20 September 2017

Wilfred Lieberthal

6

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Europe PubMed Central

PubMed publication ID

20 September 2017

John H Schwartz

7

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Europe PubMed Central

PubMed publication ID

20 September 2017

Steven C Borkan

8

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Europe PubMed Central

PubMed publication ID

20 September 2017

publication date

30 November 2004

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Europe PubMed Central

PubMed publication ID

20 September 2017

American Journal of Physiology - Renal Physiology

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Europe PubMed Central

PubMed publication ID

20 September 2017

288

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Europe PubMed Central

PubMed publication ID

20 September 2017

4

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Europe PubMed Central

PubMed publication ID

20 September 2017

F703-13

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Europe PubMed Central

PubMed publication ID

20 September 2017

Mechanism of activation and function of protein kinase B.

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00189.2004

21 January 2018

Role of apoptosis in the pathogenesis of acute renal failure

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00189.2004

21 January 2018

Ten years of protein kinase B signalling: a hard Akt to follow

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00189.2004

21 January 2018

Wnt signaling: a common theme in animal development

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00189.2004

21 January 2018

Glycogen synthase kinase-3beta inhibitors prevent cellular polyglutamine toxicity caused by the Huntington's disease mutation

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00189.2004

21 January 2018

Lithium activates the serine/threonine kinase Akt-1 and suppresses glutamate-induced inhibition of Akt-1 activity in neurons

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00189.2004

21 January 2018

Long term lithium treatment suppresses p53 and Bax expression but increases Bcl-2 expression. A prominent role in neuroprotection against excitotoxicity

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00189.2004

21 January 2018

Wnt-1 signaling inhibits apoptosis by activating beta-catenin/T cell factor-mediated transcription

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00189.2004

21 January 2018

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00189.2004

21 January 2018

Selective small-molecule inhibitors of glycogen synthase kinase-3 activity protect primary neurones from death

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00189.2004

21 January 2018

Cellular survival: a play in three Akts

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00189.2004

21 January 2018

Akt Phosphorylation of BAD Couples Survival Signals to the Cell-Intrinsic Death Machinery

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00189.2004

21 January 2018

GSK-3: tricks of the trade for a multi-tasking kinase

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00189.2004

21 January 2018

Mechanisms and consequences of activation of protein kinase B/Akt

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00189.2004

21 January 2018

Induction of apoptosis in fibroblasts by c-myc protein

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00189.2004

21 January 2018

GSK-3: new thoughts on an old enzyme

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00189.2004

21 January 2018

Akt participation in the Wnt signaling pathway through Dishevelled

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00189.2004

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00189.2004

21 January 2018

Lithium inhibits aluminum-induced apoptosis in rabbit hippocampus, by preventing cytochrome c translocation, Bcl-2 decrease, Bax elevation and caspase-3 activation

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00189.2004

21 January 2018

The multifaceted roles of glycogen synthase kinase 3beta in cellular signaling

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00189.2004

21 January 2018

Valproate regulates GSK-3-mediated axonal remodeling and synapsin I clustering in developing neurons

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00189.2004

21 January 2018

Lithium stimulates progenitor proliferation in cultured brain neurons.

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00189.2004

21 January 2018

Inhibitory effect of wortmannin on phosphatidylinositol 3-kinase-mediated cellular events

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00189.2004

21 January 2018

PPARdelta is an APC-regulated target of nonsteroidal anti-inflammatory drugs

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00189.2004

21 January 2018

Identification of c-MYC as a target of the APC pathway

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00189.2004

21 January 2018

Roles of ubiquitin-mediated proteolysis in cell cycle control

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00189.2004

21 January 2018

PDGF induces an early and a late wave of PI 3-kinase activity, and only the late wave is required for progression through G1.

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00189.2004

21 January 2018

IGF-1 inhibits the mitochondrial apoptosis program in mesangial cells exposed to high glucose

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00189.2004

21 January 2018

A molecular mechanism for the effect of lithium on development

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00189.2004

21 January 2018

Neoplastic transformation of RK3E by mutant beta-catenin requires deregulation of Tcf/Lef transcription but not activation of c-myc expression

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00189.2004

21 January 2018

Mechanisms of apoptosis and its potential role in renal tubular epithelial cell injury

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00189.2004

21 January 2018

Enhanced glycogen synthase kinase-3beta activity mediates hypoxia-induced apoptosis of vascular smooth muscle cells and is prevented by glucose transport and metabolism

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00189.2004

21 January 2018

Wnt signaling protects 3T3-L1 preadipocytes from apoptosis through induction of insulin-like growth factors

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00189.2004

21 January 2018

Expression and regulation of neuronal apoptosis inhibitory protein during adipocyte differentiation

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00189.2004

21 January 2018

Glycogen synthase kinase 3 (GSK-3) inhibitors as new promising drugs for diabetes, neurodegeneration, cancer, and inflammation

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00189.2004

21 January 2018

Lithium inhibits caspase 3 activation and dephosphorylation of PKB and GSK3 induced by K+ deprivation in cerebellar granule cells

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00189.2004

21 January 2018

IGF-II induces rapid beta-catenin relocation to the nucleus during epithelium to mesenchyme transition

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00189.2004

21 January 2018

Apoptosis and APC in colorectal tumorigenesis

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00189.2004

21 January 2018

IGF-I inhibits apoptosis induced by serum withdrawal, but potentiates TNF-alpha-induced apoptosis, in 3T3-L1 preadipocytes.

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00189.2004

21 January 2018

Neuroprotective effects of chronic lithium on focal cerebral ischemia in rats

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00189.2004

21 January 2018

Chronic lithium treatment robustly protects neurons in the central nervous system against excitotoxicity by inhibiting N-methyl-D-aspartate receptor-mediated calcium influx

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00189.2004

21 January 2018

Etiology and pathogenesis of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00189.2004

21 January 2018

Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00189.2004

21 January 2018

Insulin-like growth factor 1 regulates the location, stability, and transcriptional activity of beta-catenin

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00189.2004

21 January 2018

Social controls on cell survival and cell death

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00189.2004

21 January 2018

Role of apoptosis of renal tubular cells in acute renal failure: therapeutic implications

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00189.2004

21 January 2018

Chronic renal allograft dysfunction: the role of T cell-mediated tubular epithelial to mesenchymal cell transition

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00189.2004

21 January 2018

Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00189.2004

21 January 2018

Phosphatidylinositol 3-kinase/Akt stimulates androgen pathway through GSK3beta inhibition and nuclear beta-catenin accumulation

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00189.2004

21 January 2018

Apoptosis induction resulting from proteasome inhibition

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00189.2004

21 January 2018

Inhibition of ligand-independent ERK1/2 activity in kidney proximal tubular cells deprived of soluble survival factors up-regulates Akt and prevents apoptosis.

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00189.2004

21 January 2018

Chemical anoxia of tubular cells induces activation of c-Src and its translocation to the zonula adherens.

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00189.2004

21 January 2018

Wnt signalling in mammalian development and cancer

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00189.2004

21 January 2018

Growth factor withdrawal from primary human erythroid progenitors induces apoptosis through a pathway involving glycogen synthase kinase-3 and Bax.

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00189.2004

21 January 2018

Modulation of cellular apoptotic potential: contributions to oncogenesis

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00189.2004

21 January 2018

Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00189.2004

21 January 2018

Growth factors can influence cell growth and survival through effects on glucose metabolism

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00189.2004

21 January 2018

The control of beta-catenin and TCF during embryonic development and cancer.

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00189.2004

21 January 2018

A common mechanism of action for three mood-stabilizing drugs

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00189.2004

21 January 2018

Hypermutation in derepressed operons of Escherichia coli K12

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00189.2004

21 January 2018

The role of epithelial-to-mesenchymal transition in renal fibrosis

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00189.2004

21 January 2018

Identifiers

10.1152/AJPRENAL.00189.2004

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

ResearchGate publication ID

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