Effects of valproic acid derivatives on inositol trisphosphate depletion, teratogenicity, glycogen synthase kinase-3beta inhibition, and viral replication: a screening approach for new bipolar disorder drugs derived from the valproic acid core struc (Q40462745)

From Wikidata

Jump to navigation Jump to search

scientific article published on February 2005

Language	Label	Description	Also known as
English	Effects of valproic acid derivatives on inositol trisphosphate depletion, teratogenicity, glycogen synthase kinase-3beta inhibition, and viral replication: a screening approach for new bipolar disorder drugs derived from the valproic acid core struc	scientific article published on February 2005

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

Effects of valproic acid derivatives on inositol trisphosphate depletion, teratogenicity, glycogen synthase kinase-3beta inhibition, and viral replication: a screening approach for new bipolar disorder drugs derived from the valproic acid core struc (English)

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

0 references

0 references

bipolar disorder

1 reference

based on heuristic

inferred from title

author name string

B J Eickholt

1

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

G J Towers

2

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

W J Ryves

3

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

D Eikel

4

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

K Adley

5

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

L M J Ylinen

6

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

N H Chadborn

7

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

A J Harwood

8

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

H Nau

9

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

R S B Williams

10

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

publication date

1 February 2005

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

Molecular Pharmacology

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

67

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

5

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

1426-1433

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

Coaxing HIV-1 from resting CD4 T cells: histone deacetylase inhibition allows latent viral expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360212

22 September 2017

Differential enantioselective effects of pentyl-4-yn-valproate on spatial learning in the rat, and neurite outgrowth and cyclin D3 expression in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360212

22 September 2017

Modulation of inositol 1,4,5-triphosphate concentration by prolyl endopeptidase inhibition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360212

22 September 2017

Restriction of lentivirus in monkeys

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360212

22 September 2017

A common mechanism of action for three mood-stabilizing drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360212

22 September 2017

Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360212

22 September 2017

The effect of divalproex sodium on viral load: a retrospective review of HIV-positive patients with manic syndromes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360212

22 September 2017

The use of valproic acid in HIV-positive patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360212

22 September 2017

Valproate: a reappraisal of its pharmacodynamic properties and mechanisms of action

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360212

22 September 2017

Repression by Ume6 involves recruitment of a complex containing Sin3 corepressor and Rpd3 histone deacetylase to target promoters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360212

22 September 2017

Lithium inhibits glycogen synthase kinase-3 activity and mimics wingless signalling in intact cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360212

22 September 2017

A molecular mechanism for the effect of lithium on development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360212

22 September 2017

Definition of a metal-dependent/Li(+)-inhibited phosphomonoesterase protein family based upon a conserved three-dimensional core structure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360212

22 September 2017

Neural and developmental actions of lithium: a unifying hypothesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360212

22 September 2017

On the development of alternative antiepileptic drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360212

22 September 2017

Valproic Acid-Induced Neural Tube Defects in Mouse and Human: Aspects of Chirality, Alternative Drug Development, Pharmacokinetics and Possible Mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360212

22 September 2017

The mood-stabilizing agent valproate inhibits the activity of glycogen synthase kinase-3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360212

25 September 2017

Loss of a prolyl oligopeptidase confers resistance to lithium by elevation of inositol (1,4,5) trisphosphate.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360212

17 June 2018

Further branching of valproate-related carboxylic acids reduces the teratogenic activity, but not the anticonvulsant effect

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360212

17 June 2018

Studies on the teratogen pharmacophore of valproic acid analogues: evidence of interactions at a hydrophobic centre.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360212

3 July 2018

Valproate decreases inositol biosynthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360212

20 August 2018

Increased human cytomegalovirus replication in fibroblasts after treatment with therapeutical plasma concentrations of valproic acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360212

20 August 2018

Teratogenicity of valproate conjugates with anticonvulsant activity in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360212

20 August 2018

Two peptidase activities decrease in treated bipolar disorder not schizophrenic patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360212

20 August 2018

Histone deacetylase is a target of valproic acid-mediated cellular differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360212

20 August 2018

Neuroprotective activities of sodium valproate in a murine model of human immunodeficiency virus-1 encephalitis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360212

20 August 2018

Suicide risk in bipolar disorder during treatment with lithium and divalproex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360212

20 August 2018

Chronic lithium and sodium valproate both decrease the concentration of myoinositol and increase the concentration of inositol monophosphates in rat brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360212

20 August 2018

Lithium and valproate decrease the membrane phosphatidylinositol/phosphatidylcholine ratio

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360212

20 August 2018

Chronic treatment with both lithium and sodium valproate may normalize phosphoinositol cycle activity in bipolar patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360212

20 August 2018

Valproate regulates GSK-3-mediated axonal remodeling and synapsin I clustering in developing neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360212

20 August 2018

Chronic treatment of human astrocytoma cells with lithium, carbamazepine or valproic acid decreases inositol uptake at high inositol concentrations but increases it at low inositol concentrations.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360212

20 August 2018

Chemical and kinetic mechanism of the inositol monophosphatase reaction and its inhibition by Li+.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360212

20 August 2018

Effects of haloperidol, lithium, and valproate on phosphoinositide turnover in rat brain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360212

20 August 2018

A new model for embryotoxicity testing: teratogenicity and pharmacokinetics of valproic acid following constant-rate administration in the mouse using human therapeutic drug and metabolite concentrations

1 reference

https://pubmed.ncbi.nlm.nih.gov/15687223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The hepatotoxicity of valproic acid and its metabolites in rats. II. Intermediary and valproic acid metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/15687223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics and antiepileptic activity of valproyl hydroxamic acid derivatives

1 reference

https://pubmed.ncbi.nlm.nih.gov/15687223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Valnoctamide, valpromide and valnoctic acid are much less teratogenic in mice than valproic acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/15687223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An assay for glycogen synthase kinase 3 (GSK-3) for use in crude cell extracts

1 reference

https://pubmed.ncbi.nlm.nih.gov/15687223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1124/MOL.104.009308

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q40462745&oldid=1672506045"