Janus kinases affect thrombopoietin receptor cell surface localization and stability (Q40420997)

20 September 2017

title

Janus kinases affect thrombopoietin receptor cell surface localization and stability (English)

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20 September 2017

author

Stefan N Constantinescu

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20 September 2017

Yohan Royer

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20 September 2017

Judith Staerk

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20 September 2017

Marcel Costuleanu

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20 September 2017

Pierre J Courtoy

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20 September 2017

language of work or name

English

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publication date

16 May 2005

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Journal of Biological Chemistry

20 September 2017

published in

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20 September 2017

volume

280

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20 September 2017

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20 September 2017

page(s)

27251-27261

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Stimulation of megakaryocytopoiesis and thrombopoiesis by the c-Mpl ligand.

20 September 2017

cites work

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The c-Mpl ligand (thrombopoietin) stimulates tyrosine phosphorylation of Jak2, Shc, and c-Mpl

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Thrombopoietin potentiates activation of human platelets in association with JAK2 and TYK2 phosphorylation

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Thrombopoietin signal transduction requires functional JAK2, not TYK2

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The N-terminal domain of Janus kinase 2 is required for Golgi processing and cell surface expression of erythropoietin receptor

21 January 2018

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Novel role of Janus kinase 1 in the regulation of oncostatin M receptor surface expression.

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The amino-terminal region of Tyk2 sustains the level of interferon alpha receptor 1, a component of the interferon alpha/beta receptor

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21 January 2018

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The tyrosine kinase Tyk2 controls IFNAR1 cell surface expression.

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Jak3-independent trafficking of the common gamma chain receptor subunit: chaperone function of Jaks revisited

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Janus kinase (Jak) subcellular localization revisited: the exclusive membrane localization of endogenous Janus kinase 1 by cytokine receptor interaction uncovers the Jak.receptor complex to be equivalent to a receptor tyrosine kinase

21 January 2018

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Internalization of the thrombopoietin receptor is regulated by 2 cytoplasmic motifs

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Human interleukin-10-related T cell-derived inducible factor: molecular cloning and functional characterization as an hepatocyte-stimulating factor

21 January 2018

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Generation of mammalian cells stably expressing multiple genes at predetermined levels.

21 January 2018

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Il-3-dependent mouse clones that express B-220 surface antigen, contain Ig genes in germ-line configuration, and generate B lymphocytes in vivo.

21 January 2018

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A JAK1/JAK2 chimera can sustain alpha and gamma interferon responses.

21 January 2018

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Use of a selectable marker regulated by alpha interferon to obtain mutations in the signaling pathway

21 January 2018

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21 January 2018

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21 January 2018

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The erythropoietin receptor cytosolic juxtamembrane domain contains an essential, precisely oriented, hydrophobic motif

21 January 2018

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Active and inactive orientations of the transmembrane and cytosolic domains of the erythropoietin receptor dimer

21 January 2018

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Proteasome inhibitors: valuable new tools for cell biologists

21 January 2018

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Protein degradation in cultured cells. II. The uptake of chloroquine by rat fibroblasts and the inhibition of cellular protein degradation and cathepsin B1.

21 January 2018

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Cathepsin L. A New Proteinase from Rat-Liver Lysosomes

21 January 2018

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Mapping of a region within the N terminus of Jak1 involved in cytokine receptor interaction

21 January 2018

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Autosomal SCID caused by a point mutation in the N-terminus of Jak3: mapping of the Jak3-receptor interaction domain

21 January 2018

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21 January 2018

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Inactivation of erythropoietin receptor function by point mutations in a region having homology with other cytokine receptors

21 January 2018

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Direct binding to and tyrosine phosphorylation of the alpha subunit of the type I interferon receptor by p135tyk2 tyrosine kinase

21 January 2018

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A novel cytoplasmic homology domain in interferon receptors

21 January 2018

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Oligomerization and scaffolding functions of the erythropoietin receptor cytoplasmic tail.

21 January 2018

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Control of Thrombopoietin-Induced Megakaryocytic Differentiation by the Mitogen-Activated Protein Kinase Pathway

21 January 2018

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Tyk2 plays a restricted role in IFN alpha signaling, although it is required for IL-12-mediated T cell function

21 January 2018

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Principles of interleukin (IL)-6-type cytokine signalling and its regulation

21 January 2018

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A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera

21 January 2018

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Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis

21 January 2018

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A gain-of-function mutation of JAK2 in myeloproliferative disorders

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M501376200

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20 September 2017

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